Rchr
J-GLOBAL ID:200901091454670349
Update date: Mar. 12, 2024
Tomioka Yoshihisa
トミオカ ヨシヒサ | Tomioka Yoshihisa
Affiliation and department:
Job title:
Professor
Research field (3):
Tumor diagnostics and therapeutics
, Clinical pharmacy
, Functional biochemistry
Research theme for competitive and other funds (13):
- 2019 - 2022 Search for molecules that control the CD39-CD73-adenosine cascade and expand into drug discovery
- 2016 - 2019 Investigation of the modified nucleic acid for novel cancer evaluation marker candidates and its diagnostic application.
- 2016 - 2018 Elucidation of the mechanism of radioresistance in cancer cells using trans-omics approach and development of clinical biomarkers for radiotherapy.
- 2014 - 2017 A novel immunotherapy of autoimmune disease by agonistic toll-like receptor 4 antibody
- 2013 - 2016 Research of sphingolipids as a novel tumor marker for clinical study
- 2012 - 2016 Effect of docosenoic acid and icosenoic acid on the type 2 diabetic mellitus and atopic dermatitis.
- 2011 - 2013 Construction of a practical education system for pharmacy students, pharmacists, and teachers with case follow-up
- 2008 - 2010 Analysis of functional significance of a newly discovered brain-specific transporter
- 2005 - 2006 Basic Study for the Design and the Preparation of the Artificial Protein Modules and its Pharmaceutical Applications
- 2003 - 2004 Basic Study for the Design and the Preparation of the Artificial Drug Binding Protein Modules and its Pharmaceutical Applications.
- 2002 - 2003 Development of diagnosis of Atopic Dermatitis by simple and high-sensitive determination method of LTE4
- 1998 - 2000 A Study on Designed Hapten Aimed at Anti-ciguatoxin Monoclonal Antibody
- 1998 - 1999 抗生理活性物質抗体の構造解析と機能性ペプチド分子創生への応用
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Papers (175):
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Cheng-Yang Hsieh, Po-Wei Tsai, Yoshihisa Tomioka, Yotaro Matsumoto, Yasutoshi Akiyama, Ching-Chiung Wang, Lemmuel L. Tayo, Chia-Jung Lee. Chronopharmacology of diuresis via metabolic profiling and key biomarker discovery of the Traditional Chinese Prescription Ji-Ming-San using tandem mass spectrometry in rat models. Phytomedicine. 2023. 155260-155260
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Toma Oshita, Shun Watanabe, Takafumi Toyohara, Ryota Kujirai, Koichi Kikuchi, Takehiro Suzuki, Chitose Suzuki, Yotaro Matsumoto, Jun Wada, Yoshihisa Tomioka, et al. Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease. Scientific reports. 2023. 13. 1. 12508-12508
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Taku Nakai, Yuma Iwamura, Koichiro Kato, Ikuo Hirano, Yotaro Matsumoto, Yoshihisa Tomioka, Masayuki Yamamoto, Norio Suzuki. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice. Blood advances. 2023
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蓑輪 圭太, 秋山 由雅子, 笠原 朋子, 何 欣蓉, 前川 正充, 菊池 晃一, 豊原 敬文, 鈴木 健弘, 鈴木 千登世, 鯨井 涼太, et al. Elobixibat投与マウスにおける胆汁酸および腸内細菌叢の検討. 日本腎臓学会誌. 2023. 65. 3. 294-294
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Akitaka Yamasaki, Kumiko Maruyama-Takahashi, Kento Nishida, Shogo Okazaki, Kouki Okita, Yasutoshi Akiyama, Hideaki Suzuki, Yuichi Endo, Kazue Masuko, Takashi Masuko, et al. CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2 / CD98 antibody inhibits the growth signal of human breast cancer cells. Genes to Cells. 2023
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MISC (101):
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蓑輪圭太, 秋山由雅子, 笠原朋子, 何欣蓉, 前川正充, 菊池晃一, 豊原敬文, 鈴木健弘, 鈴木千登世, 鯨井涼太, et al. Elobixibat投与マウスにおける胆汁酸および腸内細菌叢の検討. 日本腎臓学会誌(Web). 2023. 65. 3
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金光祥臣, 三島英換, 松本洋太郎, 前川正充, 前川正充, 菊地晃一, 三枝大輔, 阿部高明, 阿部高明, 眞野成康, et al. Quantitative analysis of gut microbiota-derived metabolites by LC-MS sheds light on the gut-kidney axis on kidney disease. JSBMS Letters. 2021. 46. Supplement
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秋山由雅子, 前川正充, 菊地晃一, 何欣蓉, 一條真梨子, 鈴木千登世, 渡邉駿, 豊原敬文, 鈴木健弘, 富岡佳久, et al. 腸内細菌叢と胆汁酸の調節による腎不全治療. 日本腎臓学会誌(Web). 2021. 63. 4
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秋山由雅子, 前川正充, 金光祥臣, 菊地晃一, 何欣蓉, 三島英換, 鈴木健弘, 一條真梨子, 鈴木千登世, 眞野成康, et al. アデニン誘発腎不全マウスにおけるエロビキシバットの効果. 日本腎臓学会誌(Web). 2020. 62. 4
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渡辺匠, 平本航大, 沼倉忠久, 滝田克也, 宮内栄作, 突田容子, 杉浦久敏, 松本洋太郎, 富岡佳久. 修飾核酸一斉定量系を用いたCOPD早期発見手法の開発検討. 日本薬学会東北支部大会講演要旨集. 2020. 59th
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Books (9):
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病気と薬 パーフェクトBOOK2009
南山堂 2009
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わかりやすい薬学生のための病態生理と薬物治療
2008
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病気と薬 パーフェクトBOOK2008
南山堂 2008
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シンプル生化学 改訂第5版
2008
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Pharmacotherapy: A pathophysiologic approach
ブレーン出版 2007
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Professional career (2):
- 博士(薬学) (Tohoku University)
- 薬学修士 (Tohoku University)
Committee career (6):
Association Membership(s) (6):
日本臨床腫瘍学会
, 日本医療薬学会
, 日本免疫学会
, 日本生化学会
, 日本癌学会
, 日本薬学会
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