Rchr
J-GLOBAL ID：200901091705960546
Update date: Feb. 01, 2024
Takahashi Tetsuyuki
タカハシ テツユキ | Takahashi Tetsuyuki
Affiliation and department：
Research field (2)：
Pharmaceuticals - health and biochemistry
, Tumor diagnostics and therapeutics
Research theme for competitive and other funds (11)：
- 2023 - 2025 飢餓誘導性hnRNP A1タンパク消失機構の解析-飢餓特異的なmiRNA依存性機構の同定と創薬・診断シーズ創成への橋渡しを目指して
- 2021 - 2024 飢餓状態でのhnRNP A1消失とそれに続くncRNA遊離による癌細胞形質の変動
- 2019 - 2020 Significance of destabilization of RNA-binding proteins as a reaction to starvation in cancer cells
- 2015 - 2019 A novel signaling crosstalk between prostaglandin E2 receptors and IGF-1 receptor as a possible molecular target for antitumor therapy
- 2015 - 2018 Role of fatty acid binding protein 4 (FABP4) as an exogenous ligand, on growth of prostate cancer cells
- 2013 - 2017 Functional roles of SV40 microRNA in host antiviral immunity.
- 2015 - 2015 Metabolic profiling of TSOD mice-derived hepatic tumors developed by long-term breeding
- 2012 - 2014 Utility of arachidonic acid metabolism-related molecules as a novel target to anti-tumor strategy
- 2010 - 2011 Novel antitumor strategies by targeting to eicosanoid receptor-mediated cellular signaling
- 2009 - 2009 抗腫瘍性ペプチドとしての可溶性エイコサノイド受容体の創成
- 2006 - 2007 Trial of inhibition of prostate cancer cell growth in the bone using bone marrow-derived stem cells
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Papers (30)：
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Tetsuyuki Takahashi, Yuri Ando, Hirona Ichikawa, Koichi Tsuneyama, Takao Hijikata. Serum/glucose starvation strikingly reduces heterogeneous nuclear ribonucleoprotein A1 protein and its target, cyclin D1. The FEBS Journal. 2023. 290. 16. 4126-4144
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Tetsuyuki Takahashi, Hirona Ichikawa, Yukiko Okayama, Manami Seki, Takao Hijikata. SV40 miR-S1 and Cellular miR-1266 Sequester Each Other from Their Targets, Enhancing Telomerase Activity and Viral Replication. Non-Coding RNA. 2022. 8. 4. 57-57
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Misa Tokorodani, Hirona Ichikawa, Katsutoshi Yuasa, Tetsuyuki Takahashi, Takao Hijikata. SV40 microRNA miR-S1-3p downregulates the expression of T antigens to control viral DNA replication, and TNFα and IL-17F expression. Biological and Pharmaceutical Bulletin. 2020. 43. 11. 1715-1728
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Tetsuyuki Takahashi, Hirona Ichikawa, Yuuki Morimoto, Koichi Tsuneyama, Takao Hijikata. Inhibition of EP2/EP4 prostanoid receptor-mediated signaling suppresses IGF-1-induced proliferation of pancreatic cancer BxPC-3 cells via upregulating gamma-glutamyl cyclotransferase expression. Biochemical and Biophysical Research Communication. 2019. 516. 2. 388-396
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Tetsuyuki Takahashi, Ulrich Deuschle, Shu Taira, Takeshi Nishida, Makoto Fujimoto, Takao Hijikata, Koichi Tsuneyama. Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation. Hepatology International. 2018. 12. 3. 254-261
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MISC (38)：
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高橋徹行, 若井駿, 船村麻衣, 市川裕菜, 土方貴雄. 飢餓誘導性hnRNP A1タンパク消失機構に関与するmiRNAの解析. 日本薬学会第143年会. 2023
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市川裕菜, 関愛美, 高橋徹行, 土方貴雄. 同種ウイルス粒子を用いたポリオーマウイルス関連疾患の新規治療戦略の検討. 日本薬学会第143年会. 2023
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坂口陽花, 市川裕菜, 高橋徹行, 土方貴雄. ポリオーマウイルスのsmall t抗原によるIL-17F発現誘導機構の解明. 日本薬学会第143年会. 2023
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安藤悠莉, 高橋徹行, 市川裕菜, 土方貴雄. 飢餓状態下で起こるhnRNP A1タンパク消失に連動するCCND1レベルの低下. 日本薬学会第142年会. 2022
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高橋徹行, 市川裕菜, 土方貴雄. SV40-miR-S1はテロメラーゼ発現調節を介して正常細胞の形質転換へ寄与する. 日本薬学会第141年会. 2021
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Professional career (1)：
Work history (2)：
- 2015/09 - 現在 Lecturer
- 2005/04 - 2015/08 Assistant Professor
Awards (1)：
Association Membership(s) (4)：
日本薬学会
, American Association for Cancer Research
, 日本癌転移学会
, 日本癌学会
