Rchr
J-GLOBAL ID：200901092573853300   Update date: Jan. 31, 2024

Oyama Fumitaka

オヤマ フミタカ | Oyama Fumitaka
Affiliation and department：
Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science

About Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science


Job title： Professor,Visiting Research Scientist, Laboratory for Structural Neuropathology,RIKEN BSI, Japan
Research field  (6)： Pathobiochemistry ,  Applied biochemistry ,  Genetics ,  Biochemistry ,  Laboratory animal science ,  Neuroanatomy and physiology
Research keywords  (12)： ほ乳類キチナーゼ ,  キチン含有生物の動物食糧への利用 ,  酵素の構造と機能 ,  キチン・キトサン ,  アレルギー・喘息 ,  ヒトの疾患に関係する遺伝子 ,  firefly luciferase ,  Enzyme strucutr-function relationship ,  Chitin・chitosan ,  allergy and asthma ,  Alzheimer's disease ,  Disease-related genes
Research theme for competitive and other funds  (26)：
  • 2016 - 2019 Is acidic mammalian chitinase a major glycosidase in the stomachs of mouse and porcine?
  • 2009 - 2019 Studies on the structure and function relationships of proteins using the biotechnological methods
  • 2009 - 2019 Application of animal biomass for medical and pharmacological areas
  • 2009 - 2019 Development of novel methods for isolation and characterization of cells and nucleic acids
  • 2005 - 2015 Biochemical and molecular cell biological analysis of human disease-related genes
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Papers (49)：
  • Kazuaki Okawa, Eri Tabata, Yuta Kida, Kyohei Uno, Hidetoshi Suzuki, Minori Kamaya, Peter O. Bauer, Fumitaka Oyama. Irreversible evolutionary loss of chitin-degrading ability in the chitinase-like protein Ym1 under positive selection in rodents. Protein Science. 2023
  • Daisuke Yamanaka, Kento Suzuki, Masahiro Kimura, Fumitaka Oyama, Yoshiyuki Adachi. Functionally modified chitotriosidase catalytic domain for chitin detection based on split-luciferase complementation. Carbohydrate polymers. 2022. 282. 119125-119125
  • Maiko Uehara, Eri Tabata, Mikoto Okuda, Yukari Maruyama, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama. Robust chitinolytic activity of crab-eating monkey (Macaca fascicularis) acidic chitinase under a broad pH and temperature range. Scientific Reports. 2021. 11. 1
  • Eri Tabata, Akihiro Itoigawa, Takumi Koinuma, Hiroshi Tayama, Akinori Kashimura, Masayoshi Sakaguchi, Vaclav Matoska, Peter O Bauer, Fumitaka Oyama. Noninsect-Based Diet Leads to Structural and Functional Changes of Acidic Chitinase in Carnivora. Molecular Biology and Evolution. 2021
  • Satoshi Wakita, Yasusato Sugahara, Masayuki Nakamura, Syunsuke Kobayashi, Kazuhisa Matsuda, Chinatsu Takasaki, Masahiro Kimura, Yuta Kida, Maiko Uehara, Eri Tabata, et al. Mouse Acidic Chitinase Effectively Degrades Random-Type Chitosan to Chitooligosaccharides of Variable Lengths under Stomach and Lung Tissue pH Conditions. Molecules. 2021. 26. 21. 6706-6706
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MISC (96)：
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Books (4)：
  • Update article: Chloroquine myopathy suggests that tau is degraded in lysosomes : implication for the formation of paired helical filaments in Alzheimer’s disease.
    Neurosci. Res. Elsevier 1998
  • Nonneural tau: transient upregulation and subsequent accumulation of big and small tau in chloroquine myopathy.
    In Alzheimer's Disease: Biology, Diagnosis and Therapeutics (ed. by Iqbal et al.) 1997
  • Modified nested PCR for the detection of minor molecular variants.
    Neuroscience Protocols. Elsevier 1996
  • 3'-end labeling of DNA fragments by AMV-reverse transcriptase.
    Nucleic Acids Symposium Series. Oxford University Press 1988
Lectures and oral presentations  (65)：
  • Analysis of mammalian chitinase mRNA levels in human and mouse tissues
    (The 2014 Annual Meeting of Japan Society for Bioscience, Biotechnology and Agrochemistry 2014)
  • Cloning and expression in Escherichia coli and functional identification of Caulobacter glucoamylase
    (The 2014 Annual Meeting of Japan Society for Bioscience, Biotechnology and Agrochemistry 2014)
  • Characterization of Protein A-mouse acidic mammalian chitinase-V5-His expressed in periplasmic space of Escherichia coli
    (The 2014 Annual Meeting of Japan Society for Bioscience, Biotechnology and Agrochemistry 2014)
  • Expression in Escherichia coli and characterization of two chitinases from Listeria innocua
    (The 2014 Annual Meeting of Japan Society for Bioscience, Biotechnology and Agrochemistry 2014)
  • Preparation of chitin oligomers by hydrolysis with concentrated hydrochloric acid
    (10th International Conference of the Asian Pacific Chitin Chitosan Symposium 2013)
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Works (1)：
  • Alternative Splicing of fibronectin pre-mRNA in Human Tissues
    1992 - 1992
Education (6)：
  • - 1985 東北大学大学院 農学研究科 農芸化学専攻
  • - 1985 Tohoku University Graduate School of Agricultural Science Agricultural Chemistry Program
  • - 1982 東北大学大学院 農学研究科 農芸化学専攻
  • - 1982 Tohoku University Graduate School of Agricultural Science Agricultural Chemistry Program
  • - 1980 Ibaraki University College of Agriculture
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Professional career (3)：
  • BS (Ibaraki University)
  • M.S. (Agricultural Chemistry) (Tohoku University)
  • Ph.D. (Agricultural Chemistry) (Tohoku University)
Work history (16)：
  • 2015/04 - 現在 Kogakuin University School of Advanced Engineering, Department of Chemistry and Life Science
  • 2009 - 現在 Professor, Biotechnology Laboratory, Department of Applied Chemistry, Faculty of Engineering, Kogakuin University
  • 2009 - 2015/03 Kogakuin University Faculty of Engineering, Department of Applied Chemistry
  • 2009 - 2012 RIKEN
  • 2009 - 2012 Visiting Research Scientist, Laboratory for Structural Neuropathology, RIKEN Brain Science Institute
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Committee career (4)：
  • 2014/01 - 2014/12 Japanese Society for Chitin and Chitosan Board of directors
  • 2014/01 - 2014/12 Board of directors, the Japanese Society for Chitin and Chitosan
  • 2011/01 - 2013/12 Japanese Society for Chitin and Chitosan Board member
  • 2011/01 - 2013/12 Board of the Japanese Society for Chitin and Chitosan
Association Membership(s) (5)：
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  アメリカ人類遺伝学会 ,  日本キチン・キトサン学会 ,  American Society of Human Genetics ,  Japanese Society for Chitin and Chitosan
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