Rchr
J-GLOBAL ID:200901092670339955   Update date: Jan. 31, 2024

Kunisada Takahiro

クニサダ タカヒロ | Kunisada Takahiro
Affiliation and department:
Job title: Professor
Research field  (14): Medical biochemistry ,  General surgery, pediatric surgery ,  Regenerative dentistry and dental engineering ,  Orthopedics ,  Conservative dentistry and endodontics ,  Pharmacology ,  Gastroenterology ,  Experimental pathology ,  Fetal medicine/Pediatrics ,  Cell biology ,  Developmental biology ,  Ophthalmology ,  Immunology ,  Dermatology
Research keywords  (28): サイトケラチンプロモーター ,  低タンパク ,  移植 ,  ヒトiPS細胞 ,  色素性じん麻疹症 ,  網膜幹細胞 ,  Sox1 ,  浮遊培養 ,  ヒトES細胞 ,  C-Kit ,  エンドセリン3 ,  レチノイン酸 ,  細胞分化 ,  セリン・スレオニンキナーゼ ,  神経細胞 ,  steel因子 ,  レンズ ,  モノクローナル抗体 ,  眼様構造 ,  網膜 ,  網膜色素上皮 ,  試験管内分化 ,  幹細胞 ,  トランスジェニックマウス ,  再生医療 ,  神経堤細胞 ,  色素細胞 ,  ES細胞
Research theme for competitive and other funds  (37):
  • 2019 - 2022 Maintenance of melanocyte stem cell function by HMGB2 gene expressed in hair follicles.
  • 2016 - 2019 色素細胞幹細胞のニッシェ因子の解明
  • 2016 - 2017 幹細胞を標的とした研究
  • 2013 - 2016 Glial cells differentiation of MeCP2 deficient ES/iPS cells and pathophysiology of Rett syndrome
  • 2013 - 2016 色素細胞の系譜と分布から予想される脊椎動物の神経堤細胞の起源
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Papers (191):
  • Hitomi Aoki, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada. Postnatal Expression of Kitl Affects Pigmentation of the Epidermis. The Journal of investigative dermatology. 2023
  • Yuta Shimizu, Tomoko Takeda-Kawaguchi, Izumi Kuroda, Yasuaki Hotta, Hideya Kawasaki, Takahiko Hariyama, Toshiyuki Shibata, Yukihiro Akao, Takahiro Kunisada, Junichi Tatsumi, et al. Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis. Journal of Periodontal Research. 2022. 57. 1. 162-172
  • Madeleine Le Coz, Zackie Aktary, Natsuki Watanabe, Ichiro Yajima, Marie Pouteaux, Nisamanee Charoenchon, Tsutomu Motohashi, Takahiro Kunisada, André Corvelo, Lionel Larue. Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects. The Journal of investigative dermatology. 2021. 141. 5. 1363-1366
  • Hitomi Aoki, Chikara Abe, Akira Hara, Tatsuhiko Miyazaki, Hironobu Morita, Takahiro Kunisada. Induced genetic ablation of Rest leads to the alteration of stimulus-induced response of the vagal nerve. Genes to Cells. 2021. 26. 2. 45-55
  • Tsutomu Motohashi, Norito Kawamura, Natsuki Watanabe, Daisuke Kitagawa, Naoki Goshima, Takahiro Kunisada. Sox10 Functions as an Inducer of the Direct Conversion of Keratinocytes Into Neural Crest Cells. Stem Cells and Development. 2020. 29. 23. 1510-1519
more...
MISC (81):
  • 小足 周平, 青木 仁美, 柴田 敏之, 國貞 隆弘, 手塚 建一, 澁谷 俊昭. ZFNを用いたヒト歯髄細胞におけるHLAゲノムエディティング. 日本歯周病学会会誌. 2018. 60. 春季特別. 126-126
  • H. Aoki, T. Kunisada. Induced haploinsufficiency of kit receptor tyrosine kinase impairs development of central nervous system. JOURNAL OF NEUROCHEMISTRY. 2017. 142. 137-137
  • Takuro Matsumoto, Atsushi Suetsugu, Kosuke Hasegawa, Miki Nakamura, Hitomi Aoki, Takahiro Kunisada, Hisashi Tsurumi, Masahito Shimizu, Robert M. Hoffman. Color-coded imaging of the tumor microenvironment of malignant lymphoma in a syngeneic mouse model. CANCER RESEARCH. 2016. 76
  • Kosuke Hasegawa, Atsushi Suetsugu, Miki Nakamura, Takuro Matsumoto, Hitomi Aoki, Takahiro Kunisada, Masahito Shimizu, Robert M. Hoffman. Imaging of colon cancer-cell mitosis within liver metastasis in nude mice. CANCER RESEARCH. 2016. 76
  • Takuro Matsumoto, Atsushi Suetsugu, Yuhei Shibata, Nobuhiko Nakamura, Hitomi Aoki, Takahiro Kunisada, Masahito Shimizu, Hisashi Tsurumi, Robert M. Hoffman. Development of a syngeneic metastatic mouse model of malignant lymphoma. CANCER RESEARCH. 2015. 75
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Patents (3):
Lectures and oral presentations  (3):
  • 細胞資源としての歯髄細胞の可能性
    (日本組織培養学会第91回大会 2018)
  • 色素異常病態マウスから探る色素異常症の分子機構
    (第117回日本皮膚科学会総会 教育講演22 2018)
  • Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor
    (1998)
Education (2):
  • 1980 - 1985 Kyoto University Graduate School of Science
  • 1975 - 1980 Kyoto University Faculty of Science
Professional career (1):
  • 理博 (京都大学)
Work history (8):
  • 2012 - 2013 Gifu University
  • 2001/02/01 - Gifu University School of Medicine
  • 1995/12/12 - 2001/01/31 Tottori University Faculty of Medicine
  • 1993/09/12 - 1995/12/10 Kyoto University Faculty of Medicine
  • 1988/01/10 - 1993/09/10 Kumamoto University School of Medicine
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Association Membership(s) (4):
日本再生医療学会 ,  日本発生生物学会 ,  日本分子生物学会 ,  日本色素細胞学会
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