2018 - 2021 Signal transduction of daidzein related to the effect of anti-influenza virus
2012 - 2015 Isolation of ingredients activating mucosal immunity from food
2008 - 2010 Research of inhibitors for nuclear transport or enzyme activity of protein kinases encoded by human herpesviruses
1999 - 2000 Functional analysis of the chemokine and chemokine receptors encoded by human herpesvirus 6.
1997 - 1998 Molecular biological analysis of the proteins which associated with the infection of human herpesvirus 6
1996 - 1997 Studies on the control of hantavirus infection and rodent
1995 - 1996 Mechanism of latent infection of human herpesvirus 6
1994 - 1994 ヒトヘルペスウイルス6における発現調節タンパク質の遺伝子と機能の解析
1992 - 1994 Study on pathogenesis of Human herpesvirus 6 and 7 infection
1991 - 1993 Genetical and biochemical characterizations of hemorrhagic fever with renal syndrome virus infection in mice.
1990 - 1992 分子生物学的手法を用いて腎症候性出血熱の診断法及びワクチン開発
1989 - 1991 Establishment of molecular diagnosis for hemorrhagic fever with renal syndrome virus and its application for the development of the virus free animals.
ロタウイルスの分子生物学的研究
腎症候性出血熱ウイルスの分子生物学的研究
ヒトヘルペスウイルス6のウイルス学的研究
Molecular biological studies on rotavirus.
Molecularbiological studies on HFRS
Virological studies on HHV-6
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Papers (17):
Yuka Horio, Yuji Isegawa, Mototada Shichiri. Daidzein phosphorylates and activates 5-lipoxygenase via the MEK/ERK pathway: a mechanism for inducing the production of 5-lipoxygenase metabolite that inhibit influenza virus intracellular replication: 5-Lipoxygenase activation mechanism of daidzein. The Journal of nutritional biochemistry. 2023. 114. 109276-109276
Miyu Nakayama, Emiko Nagai, Kae Yoshioka, Yuka Horio, Ryosuke, Morimoto, Ritsuko Koketsu, Yoshinobu Okuno, Toshiki Enomoto, Hiroshi Inui, et al. Effect of dietary supplementation and intranasal administration of soybean extract on resistance to influenza virus infection in mice. Food & Nutrition Journal. 2022
Ryosuke Morimoto, Akari Hanada, Chiaki Matsubara, Yuka Horio, Hidenobu Sumitani, Tokutaro Ogata, Yuji Isegawa. Anti-influenza A virus activity of flavonoids in vitro: a structure-activity relationship. Journal of Natural Medicine. 2022. 77. 1. 219-227
Ryoko Kanazawa, Ryosuke Morimoto, Yuka Horio, Hidenobu Sumitani, Yuji Isegawa. Inhibition of influenza virus replication by Apiaceae plants, with special reference to Peucedanum japonicum (Sacna) constituents. Journal of Ethnopharmacology. 2022