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J-GLOBAL ID：200901094219624150   Update date: Apr. 04, 2024

Hara Takahiro

ハラ タカヒロ | Hara Takahiro
Affiliation and department：
Ehime University

About Ehime University


Research field  (3)： Medical biochemistry ,  Immunology ,  Physiology
Research keywords  (7)： Immunology ,  Cell biology ,  Molecular biology, Biochemistry ,  cell culture ,  Microenvironment, Stromal cell ,  Cancer, Hematopoietic disorders ,  Bioactive substance
Research theme for competitive and other funds  (11)：
  • 2023 - 2026 骨微小環境による自然免疫ダイナミクスの制御機構
  • 2019 - 2022 自然免疫系を構築する骨微小環境の新規同定
  • 2016 - 2019 Analysis of immune microenvironment essential for ILC2 development
  • 2019 - 助成金
  • 2014 - 2016 Analysis of IL-7 niche in bone marrow
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Papers (27)：
  • Shinya Abe, Takuma Asahi, Takahiro Hara, Guangwei Cui, Akihiro Shimba, Shizue Tani-Ichi, Kohei Yamada, Kazuko Miyazaki, Hitoshi Miyachi, Satsuki Kitano, et al. Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow. Cell reports. 2023. 113127-113127
  • Daichi Takami, Shinya Abe, Akihiro Shimba, Takuma Asahi, Guangwei Cui, Shizue Tani-Ichi, Takahiro Hara, Keishi Miyata, Masashi Ikutani, Kiyoshi Takatsu, et al. Lung group 2 innate lymphoid cells differentially depend on local IL-7 for their distribution, activation, and maintenance in innate and adaptive immunity-mediated airway inflammation. International immunology. 2023
  • Guangwei Cui, Akihiro Shimba, Jianshi Jin, Taisaku Ogawa, Yukiko Muramoto, Hitoshi Miyachi, Shinya Abe, Takuma Asahi, Shizue Tani-Ichi, Johannes M Dijkstra, et al. A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Science immunology. 2022. 7. 76. eabj8760
  • Koichi Ikuta, Takahiro Hara, Shinya Abe, Takuma Asahi, Daichi Takami, Guangwei Cui. The Roles of IL-7 and IL-15 in Niches for Lymphocyte Progenitors and Immune Cells in Lymphoid Organs. Current topics in microbiology and immunology. 2021. 434. 83-101
  • Shizue Tani-Ichi, Keisuke Wagatsuma, Takahiro Hara, Guangwei Cui, Shinya Abe, Hitoshi Miyachi, Satsuki Kitano, Koichi Ikuta. Innate-like CD27+CD45RBhigh γδ T Cells Require TCR Signaling for Homeostasis in Peripheral Lymphoid Organs. Journal of immunology (Baltimore, Md. : 1950). 2020. 204. 10. 2671-2684
ｍore...
Books (7)：
  • 多能造血前駆細胞からリンパ球までの分化を方向付ける骨髄IL-7ニッチの同定
    医学のあゆみ 2017
  • 生体内リンパ器官におけるサイトカインニッチの解明
    感染・炎症・免疫 2015
  • T細胞における IL-7レセプターの転写制御と機能
    臨床免疫・アレルギー科 2014
  • 肝臓IL-7 の新たな機能
    感染・炎症・免疫 2013
  • IL-7産生細胞のリンパ組織内分布
    医学のあゆみ 2013
ｍore...
Lectures and oral presentations  (48)：
  • Identification of the gut microenvironment by the cytokine reporter mice
    (2021)
  • The cytokine-producing immune microenvironment for innate lymphocytes
    (2019)
  • NK細胞の分化を支持するIL-15産生性骨髄微小環境の解明
    (2019)
  • CXCL12-expressing bone marrow stromal cells express adiponectin and are targeted by Adipoq-Cre transgene
    (2018)
  • Hematopoietic cell-derived IL-15 supports the development and maintenance of NK, NKT and memory CD8 T cells in bone marrow
    (2018)
ｍore...
Education (2)：
  • 2003 - 2006 Kyoto University
  • - 2006 Kyoto University Graduate School, Division of Life Science Division of Systemic Life Science
Professional career (1)：
  • biostudies (Kyoto University)
Association Membership(s) (2)：
THE JAPANESE BIOCHEMICAL SOCIETY ,  日本免疫学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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