Hisae Oku

Homepage URL (1)： http://ph.mukogawa-u.ac.jp

Research field (2)： Pharmaceuticals - chemistry and drug development , Molecular biochemistry

Research keywords (4)：生物有機科学 , 天然物化学 , Biological Organic Science , The Chemistry of Natural Products

Research theme for competitive and other funds (12)：

2011 - 2013 Development of an assay method to search for compounds inhibiting stress-enhanced allergy
2005 - 2006 DEVELOPMENT OF NOVEL ASSAY SYSTEM FOR ANTI-ALLERGIC COMPOUNDS FROM NATURAL SOURCES AND APPLICATION
2003 - 2004 DEVELOPMENT OF NOVEL ASSAY SYSTEM FOR ANTI-ALLERGIC COMPOUNDS FROM NATURAL SOURCES AND APPLICATION
1997 - 1998 アレルギー病態における掻痒機序の解明と治療薬の開発
1998 - 抗アレルギー物質の探索を目的とする親規アッセイ法の開発と応用

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Papers (4)：

Hisae Oku, Ryoko Kanaya, Kyoko Ishiguro. Development of an Assay Method to Search for Compounds Inhibiting Stress-Enhanced Allergy. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2016. 39. 5. 874-878
Hisae Oku, Yuko Ogawa, Emiko Iwaoka, Kyoko Ishiguro. Allergy-Preventive Effects of Chlorogenic Acid and Iridoid Derivatives from Flower Buds of Lonicera japonica. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2011. 34. 8. 1330-1333
Hisae Oku, Yuko Ogawa, Emiko Iwaoka, Yu Yamaguchi, Satomi Kagota, Shinozuka Kazumasa, Masaru Kunitomo, Kyoko Ishiguro. Preventive effects of the extract of kinka-cha, a folk tea, on a rat model of metabolic syndrome. JOURNAL OF NATURAL MEDICINES. 2011. 65. 3-4. 610-616
Kimiko Watanabe, Atsuki Tomiokas, Kiyoko Tanimura, Hisae Oku, Koichiro Isoi. Uptake of AMP, ADP, and ATP in Escherichia coli W. Bioscience, Biotechnology and Biochemistry. 2011. 75. 1. 7-12

MISC (119)：

Chao Ma, Naoko Higashi, Kyoko Ishiguro, Ying Zhao, Linkui Zhang, Chenwen Zhao, Maosheng Cheng, Hisae Oku. Allergy-preventive effects of linarinic acid and its tetrahydropyrrolo[2,1-b]quinazoline derivatives isolated from Linaria vulgaris. Journal of Natural Medicines. 2018. 72. 2. 582-587
K. Ishiguro, M. Okumura, M. Miyawaki, H. Oku. Development of an assay method to search for compounds inhibiting stress-enhanced allergy. PLANTA MEDICA. 2014. 80. 16. 1524-1525
H. Oku, M. Abe, K. Maruyama, T. Yagi, K. Ishiguro. Mechanism of the purgative action of multiflorin A. PLANTA MEDICA. 2014. 80. 16. 1535-1535
Emiko IWAOKA, Hisae OKU, Munekazu IINUMA, Kyoko ISHIGURO. Development and Application of the New in vivo Assay Method for the Allergy-Preventive Substances. 2011. 60. 11-21
K. Ishiguro, H. Oku, E. Iwaokab, M. Iinuma. Allergy-preventive effects of flowers of Campsis grandiflora. PLANTA MEDICA. 2010. 76. 12. 1345-1345

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Patents (14)：

Anti-itching flavonoids and naphthoketones from Impatiens balsamina.
Naphthoaquinone derivatives for the treatment of allergies.
Isomerized linoleic acid and their salts as anti-itching agents.
Dinaphthofuranquinones, their isolation from balsam, and their use as antipruritic agents.
Evaluation and screening methods of antipruritic effect of topical drugs.

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Books (2)：

XI Hypericum patulum : in vitro culture and production of xanthones and other secondary metabolites
Biotechnology in Agriculture and Forestry 1999
XI Hypericum patulum : in vitro culture and production of xanthones and other secondary metabolites
Biotechnology in Agriculture and Forestry, 1999

Education (2)：

- 1985 Mukogawa Women's University School of Pharmacy and Pharmaceutical Sciences Department of Bio-Pharmaceutical Sciences
- 1985 Mukogawa Women's University Faculty of Pharmaceutical Science

Professional career (1)：

Work history (3)：

2016/04 - 現在 Mukogawa Women's University School of Pharmacy and Pharmaceutical Sciences
2010 - 2016/03 - 武庫川女子大学薬学部助教
1986 - - Research Associate, Mukogawa Women's University

Association Membership(s) (7)：

日本植物生理学会 , 日本東洋医学会 , KAMPO EYES , 植物化学研究会 , 日本NO学会 , 日本生薬学会 , 日本薬学会

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