Akasaki Kenji

Akasaki Kenji | Akasaki Kenji

Affiliation and department：

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (4)： Moleclular mechanisms for lysosomal localization of LAMPs , Biochemical study on lysosomal membrane glycoproteins , Degradation Mechanism of Functional Biomolecules , Biochemical Studies on Lysosomal Proteins

Research theme for competitive and other funds (3)：

1992 - 1992 キョートルフィン分解酵素の分子生物学的研究
リソソーム移行シグナルを利用したDNAワクチンの開発
Development of DNA vaccines by using lyosorome targeting signal

Papers (33)：

Fumiaki Yamaguchi, Hiroshi Sakane, Yosuke Morishita, Toshiyuki Hata, Kenji Akasaki. Importance of Glycine Preceding Pivotal Tyrosine in the Lysosome-Targeting Signal GYQTI of Lysosome-Associated Membrane Protein-1 (LAMP-1). BPB Reports. 2022. 5. 5. 99-104
Hiroshi Sakane, Junna Urabe, Saki Nakahira, Katsumi Hino, Nao Miyata, Kenji Akasaki. Involvement of lysosomal integral membrane protein-2 in the activation of autophagy. Biochemical and Biophysical Research Communications. 2020. 533. 4. 976-982
Kenji Akasaki, Hiroshi Sakane, Yusuke Ohdoi, Kenta Okamoto, Kazutaka Nushida, Toshiyuki Hata. Targeting of Wild-Type and Mutated Forms of Lysosome-Associated Membrane Protein-1 (LAMP-1) to Late Endosomes/Lysosomes Depends on Affinities of Their Cytoplasmic Tail Peptides with a Medium Subunit of Adaptor Protein Complex-3 (AP-3). BPB Reports. 2019. 2. 5. 67-72
Sakane H, Akasaki K. The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts. Biological & pharmaceutical bulletin. 2018. 41. 8. 1186-1193
Hiroshi Sakane, Tomohiko Makiyama, Satoru Nogami, Yukimi Horii, Kenji Akasaki, Hiromichi Shirataki. beta-Taxilin participates in differentiation of C2C12 myoblasts into myotubes. EXPERIMENTAL CELL RESEARCH. 2016. 345. 2. 230-238

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MISC (38)：

Delta-Tocotrienol Causes Decrease of Melanin Content in Mouse Melanoma Cells. 2010. 28. 55-55
Decrease of cholesterol in mouse melanoma causes secretion of lysosomal enzymes. 2008. 26. 56-56
Michihara Akihiro, Toda Ken, Kubo Takuo, Fujiawra Yoshiteru, Akasaki Kenji, Tsuji Hiroshi. Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes. Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University. 2006. 24. 66-67
Haraguchi Cellina, Mabuchi Tadashi, Hirata Shuji, Shoda Tomoko, Hoshi Kazuhiko, Akasaki Kenji, Yokota Sadaki. Chromatoid bodies : aggresome-like characteristics and degradation sites for organelles of spermiogenic cells. Annual report of the Faculty of Pharmacy & Pharmaceutical Sciences, Fukuyama University. 2006. 24. 64-65
Akihiro Michihara, Kenji Akasaki, Yukio Yamori, Hiroshi Tsuji. Change in the protein level of mevalonate pyrophosphate decarboxylase in tissues of mouse by pravastatin. 2004. 22. 65-66

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Books (2)：

薬系免疫学
南江堂 2018 ISBN:9784524403516
予防薬学としての衛生薬学 : 健康と環境
廣川書店 2016 ISBN:9784567472029

Education (2)：

1980 - 1985 Kyushu University Graduate School of Pharmaceutical Sciences Pharmaceutical Sciences
1976 - 1980 Kyushu University School of Pharmaceutical Sciences Pharmaceutical Chemistry

Professional career (2)：

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Work history (4)：

2006/04 - 現在 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences Professor
1996/04 - 2006/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences Associate Professor
1991/04 - 1996/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences Assistant Professor
1985/04 - 1991/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences Research Assistant

Committee career (2)：

- 現在日本生化学会評議員
2016/11 - 2020/10 日本生化学会各種受賞選考委員

Association Membership(s) (2)：

日本生化学会 , 日本薬学会

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