Rchr
J-GLOBAL ID：200901094730313490   Update date: Jan. 31, 2024

Imai Takashi

イマイ タカシ | Imai Takashi
Affiliation and department：
National Institutes for Quantum Science and Technology QST hospital

About National Institutes for Quantum Science and Technology QST hospital


Job title： Director
Homepage URL  (1)： http://www.nirs.qst.go.jp/research/review/radgenomics/index.php
Research field  (5)： Systems genomics ,  Genomics ,  Radiology ,  Medical biochemistry ,  Molecular biology
Research keywords  (2)： ゲノム科学 ,  Genome science
Research theme for competitive and other funds  (18)：
  • 2018 - 2023 癌放射線治療における稀で重篤な正常組織障害発症例のゲノムシーケンス解析
  • 2019 - 2022 口腔粘膜悪性黒色腫の重粒子線治療を中心とした集学的治療法の開発
  • 2013 - 2016 Basic Research for Carbon-Ion Radiotherapy for Breast Cancer
  • 2013 - 2016 Metabolome analysis of invaded pancreatic cancer cell line, PANC-1, after irradiation
  • 2012 - 2016 A study for single nucleotide polymorphism as a risk factor correlating to radiation pneumonitis after stereotactic body radiotherapy for non-small celllung cancer.
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Papers (147)：
  • Liqiu Ma, Yoshimitsu Sakamoto, Ken Ando, Hidetoshi Fujita, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Daniel K Ebner, Kazuhiro Kakimi, Takashi Imai, et al. Th Balance-Related Host Genetic Background Affects the Therapeutic Effects of Combining Carbon-Ion Radiation Therapy With Dendritic Cell Immunotherapy. International journal of radiation oncology, biology, physics. 2022. 112. 3. 780-789
  • K E Applegate, W Rühm, A Wojcik, M Bourguignon, A Brenner, K Hamasaki, T Imai, M Imaizumi, T Imaoka, S Kakinuma, et al. Individual response of humans to ionising radiation: governing factors and importance for radiological protection. Radiation and Environmental Biophysics. 2020. 59. 2. 185-209
  • Liqiu Ma, Yoshimitsu Sakamoto, Akinori Kanai, Hiromi Otsuka, Akihisa Takahashi, Kazuhiro Kakimi, Takashi Imai, Takashi Shimokawa. Characterization of a Novel Murine Colon Carcinoma Subline with High-Metastatic Activity Established by In Vivo Selection Method. International journal of molecular sciences. 2020. 21. 8
  • Matsuura T, Maru Y, Izumiya M, Hoshi D, Kato S, Ochiai M, Hori M, Yamamoto S, Tatsuno K, Imai T, et al. Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis. Carcinogenesis. 2019. 41. 4. 490-501
  • Daino K, Ishikawa A, Suga T, Amasaki Y, Kodama Y, Shang Y, Hirano-Sakairi S, Nishimura M, Nakata A, Yoshida M, et al. Mutational landscape of T-cell lymphoma in mice lacking the DNA mismatch repair gene Mlh1: no synergism with ionizing radiation. Carcinogenesis. 2019. 40. 2. 216-224
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MISC (64)：
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Patents (7)：
  • 乳癌患者の放射線治療における晩期有害反応リスク予測DNAマーカーセット
  • 子宮頚部腺癌の診断又は子宮頸癌の予後の診断のためのマーカー
  • 口腔癌の頚部リンパ節転移予測方法およびその予測に用いる診断キット
  • 放射線治療後における泌尿器の晩期有害反応の発症予測用DNAチップ、及びこれを用いた放射線治療後における泌尿器の晩期有害反応発症予測方法
  • Method of predicting metastasis of oral cavity cancer into cervical lymph node and diagnosis kit to be used in the prediction
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Books (7)：
  • 正常組織障害における放射線感受性遺伝子研究-遺伝子多型からのアプローチ-、癌の臨床、51(5)
    篠原出版新社 2005
  • 放射線感受性遺伝子プロジェクトの目的と意義、テーラーメイド放射線医療を目指して
    実業公報社 2003 ISBN:9784880380438
  • YACクローンの利用、分子生物学プロトコ-ル第2版
    南江堂 1999 ISBN:9784524215331
  • ATM遺伝子に隣接するNPAT遺伝子、実験医学増刊 細胞周期と癌
    羊土社 1999 ISBN:9784897060699
  • ゲノムDNAクローニング、新訂新遺伝子工学ハンドブック改訂、第3版
    羊土社 1999 ISBN:9784897066318
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Lectures and oral presentations  (16)：
  • Variants Of Cell-Cycle Regulatory Genes Are Associated With The Risk Of An Early Adverse Reaction After Radiotherapy For Cervical Cancer
    (Biotecnologia Habana 2009, Medical Applications of Biotechnology 2009)
  • Genetic Variation in Individual Sensitivity to Clinical Radiotherapy
    (Genomic Tools & Technologies Summit 2009)
  • Genetic Variation in Individual Sensitivity to Clinical Radiotherapy
    (KIDS workshop 2009 in NIRS IAEA NIRS Joint Workshop & NIRS Symposium on Radiation Protection for Children 2009)
  • The Japanese RadGenomics Project
    (International radiogenomics collaboration to predict radiotherapy outcome 2009)
  • Variants Of Cell-Cycle Regulatory Genes Are Associated With The Risk Of An Early Adverse Reaction After Radiotherapy For Cervical Cancer
    (Biotecnologia Habana 2009, Medical Applications of Biotechnology 2009)
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Education (2)：
  • - 1986 University of Tsukuba
  • Graduate School, University of Tsukuba
Professional career (1)：
  • Doctor of Agriculture
Work history (15)：
  • 2018/04 - 現在 National Institute of Radiological Sciences National Institute for Quantum and Radiological Science and Technology Medical Databank, Hospital & Department of Charged Particle Therapy Research
  • 2016/04 - 2018/03 National Institute for Quantum and Radiological Science and Technology National Institute of Radiological Sciences Supreme Researcher
  • 2011/04 - 2016 放射線医学総合研究所 プログラムリーダー
  • 2006 - 2011 - 放射線医学総合研究所 グループリーダー
  • 2001 - 2006 放射線医学総合研究所 プロジェクトリーダー
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Awards (2)：
  • 2001 - ヒトゲノム国際会議2001 ポスター賞
  • 2001 - Human Genome Meeting 2001 Poster Competition
Association Membership(s) (6)：
日本癌学会 ,  日本生化学会 ,  日本放射線影響学会 ,  Japanese Cancer Association ,  Japanese Biochemical Society ,  Japan Radiation Research Society
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