Research field (2):
Medical biochemistry
, Functional biochemistry
Research keywords (2):
自然免疫
, innate immunity
Research theme for competitive and other funds (12):
2017 - 2020 尿路病原性大腸菌に対する異所性肺コレクチンの生体防御機能の分子基盤解明
2014 - 2017 Regulation of ErbB receptors by N-glycans
2013 - 2016 Studies of pulmonary surfactant proteins on new aspects of host defense functions: anti-tumor activity and defensive activity against disease development.
2012 - 2015 Studies on molecular basis of inhibitory effect of surfactant protein A against cytotoxicity of human b-defensin3.
2014 - 抗菌ペプチドによる組織傷害をSP-Aが抑制する分子機構の解明
2014 - 肺コレクチンによるレジオネラ菌の細胞内増殖抑制の分子機構解明
2010 - 2011 Studies on host defense mechanisms of pulmonary collectins against Legionella pneumophila.
2008 - 2010 Mechanisms of host defense against pulmonaryinfection, inflammation and injury by surfactant proteins and studies on clinical applications
2008 - 2010 Analysis of the interactions of collectins with immunoglobuins and the regulation immunoglobulin functions
2008 - 2009 Studies on host defense mechanisms of pulmonary collectins against Mycobacterium avium and Legionella pneumophila.
2005 - 2006 自然免疫におけるリポ多糖認識の分子基盤
2004 - カブトガニ顆粒細胞の分泌機構
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Papers (33):
Atsushi Saitou, Yoshihiro Hasegawa, Naoki Fujitani, Shigeru Ariki, Yasuaki Uehara, Ukichiro Hashimoto, Atsushi Saito, Koji Kuronuma, Kunio Matsumoto, Hirofumi Chiba, et al. N-glycosylation regulates MET processing and signaling. Cancer science. 2022. 113. 4. 1292-1304
Naoki Fujitani, Shigeru Ariki, Yoshihiro Hasegawa, Yasuaki Uehara, Atsushi Saito, Motoko Takahashi. Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress. Biochemistry. 2021. 60. 21. 1708-1721