Rchr
J-GLOBAL ID:200901095175869769   Update date: Feb. 01, 2024

Tojima Takuro

トジマ タクロウ | Tojima Takuro
Affiliation and department:
Homepage URL  (1): http://tojimat.web.fc2.com/
Research field  (4): Neuroscience - general ,  Cell biology ,  Developmental biology ,  Biophysics
Research keywords  (19): ゴルジ体 ,  membrane traffic ,  包括脳ネットワーク ,  再生 ,  神経発生 ,  蛍光イメージング ,  神経細胞 ,  cGMP ,  cAMP ,  エンドサイトーシス ,  エキソサイトーシス ,  成長円錐 ,  軸索 ,  脳・神経 ,  カルシウム ,  軸索ガイダンス ,  calcium ,  axon guidance ,  growth cone
Research theme for competitive and other funds  (17):
  • 2021 - 2026 ゴルジ体の動態解明に基づく糖鎖修飾の制御
  • 2022 - 2025 Elucidation of mechanisms of neuronal network formation by visualization and manipuration of membrane traffic
  • 2018 - 2023 ゴルジ体を中心とした選別輸送機構の超解像ライブイメージングによる完全解明
  • 2019 - 2022 Neuronal axon guidance regulated by calcium signaling in the Golgi apparatus
  • 2019 - 2021 Visualization and manipulation of the growth cone "scrap & build" regulating neural network formation and regeneration
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Papers (40):
  • Yuuki Obata, Kazuo Kurokawa, Takuro Tojima, Miyuki Natsume, Isamu Shiina, Tsuyoshi Takahashi, Ryo Abe, Akihiko Nakano, Toshirou Nishida. Golgi retention and oncogenic KIT signaling via PLCγ2-PKD2-PI4KIIIβ activation in GIST cells. 2022
  • Takuro Tojima, Daisuke Miyashiro, Yasuhito Kosugi, Akihiko Nakano. Super-Resolution Live Imaging of Cargo Traffic Through the Golgi Apparatus in Mammalian Cells. Methods in Molecular Biology. 2022. 127-140
  • Takuro Tojima, Yasuyuki Suda, Midori Ishii, Kazuo Kurokawa, Akihiko Nakano. Spatiotemporal dissection of the trans-Golgi network in budding yeast. Journal of Cell Science. 2019. 132. 15. jcs231159-jcs231159
  • Rurika Itofusa, Takuro Tojima, Hiroyuki Kamiguchi. Visualization of clathrin-mediated endocytosis during semaphorin-guided axonal growth. Methods in Molecular Biology. 2017. 1493. 287-298
  • Hiroki Akiyama, Tetsuko Fukuda, Takuro Tojima, Viacheslav O. Nikolaev, Hiroyuki Kamiguchi. Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance. JOURNAL OF NEUROSCIENCE. 2016. 36. 20. 5636-5649
more...
MISC (5):
  • Hosono T., Yamanaka M., Tojima T., Sadamoto H., Kawabata K., Abe K., Ito E. AFM analysis of morphological changes in cerebellar granule cells induced by agonists for receptors. Biophysics. 1998. 38. 2. S201
  • Tojima T., Ito E. Expression of neuronal and glial proteins in the differentiated and non-differentiated neuroblastomaX glioma hybrid cell line. Biophysics. 1998. 38. 2. S199
  • ITO Etsuro, TOJIMA Takuro, KOJIMA Satoshi, NAKAMURA Hiroshi, TAKAGI Hiroshi, MIYAKAWA Atsuo, SUZUKI Hideo. Measurements of intracellular Ca^<2+> concentration in small active spots in nerve cells. Meeting abstracts of the Physical Society of Japan. 1998. 53. 1. 729-729
  • YAMANE Y., TOJIMA T., ITO E., YOSHIDA A., MISAWA H., SUGIYAMA T., YOSHIOKA T. Effects of expression of synapsin II and chorine acetyltransferase cDNA on the morphology of nerve cells. Biophysics. 1997. 37. S116
  • TOJIMA T., YAMANE Y., KAWABATA K., ITO E., TAKAGI H., TAKESHITA T., YOSHIOKA T., USHIKI T., ABE K. Fine structure of exocytotic aperture in nerve cells revealed by AFM. Biophysics. 1997. 37. S116
Books (5):
  • こころの科学増刊:ここまでわかった!脳とこころ
    日本評論社 2016
  • 脳科学辞典(http://bsd.neuroinf.jp/wiki/)
    2013
  • Cytoskeleton of the Nervous System, Advances in Neurobiology
    Springer 2011
  • シリーズ脳科学4:脳の発生と発達
    東京大学出版会 2008
  • ブレインサイエンス・レビュー2001
    医学書院 2001
Lectures and oral presentations  (35):
  • 高速超解像顕微鏡によるゴルジ体の時空間動態の解析
    (ExCELLSセミナー 2023)
  • ゴルジ体形成・成熟の時空間ダイナミクス
    (第95回日本生化学会大会 2022)
  • Dynamics of membrane traffic in the neuronal growth cone revealed by super-resolution live imaging
    (Neuro2022 2022)
  • 出芽酵母におけるトランスゴルジ網の槽成熟ダイナミクス
    (第22回植物オルガネラワークショップ 2021)
  • 神経成長円錐における膜交通ダイナミクス
    (第43回日本分子生物学会年会 2020)
more...
Education (3):
  • 1997 - 2002 Hokkaido University Graduate School of Science Division of Biological Sciences
  • 1994 - 1997 Hokkaido University Faculty of Science Division of Biological Sciences
  • 1993 - 1994 Hokkaido University
Professional career (1):
  • PhD (Hokkaido University)
Work history (8):
  • 2019/10 - 現在 RIKEN Center for Advanced Photonics Senior Research Scientist
  • 2016/04 - 2019/09 RIKEN Center for Advanced Photonics Live Cell Super-Resolution Imaging Research Team Research Scientist
  • 2008/04 - 2016/03 RIKEN Brain Science Institute Laboratory for Neuronal Growth Mechanisms Research Scientist
  • 2010/10 - 2014/03 PRESTO, Japan Science and Technology Agency Researcher
  • 2005/04 - 2008/03 Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute Special Postdoctoral Researcher
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Committee career (1):
  • 2015/04 - 現在 文部科学省 科学技術政策研究所 科学技術動向研究センター 専門調査員
Awards (4):
  • 2018/10 - FEBS Letters Poster Award, The 2018 Golgi meeting: Membrane Trafficking in Cell Organization and Homeostasis "Dynamics of coat and adaptor proteins at the trans-Golgi network revealed by super-resolution live imaging"
  • 2011/09 - Japan Neuroscience Society Young Investigator Award Signal transduction and membrane trafficking underlying neuronal growth cone guidance
  • 2011/03 - RIKEN RIKEN Research Incentive Award Discovery of signaling and driving mechanisms underlying axon guidance
  • 2009/06 - Japan Society for Cell Biology Young Scientist Award for Presentation Asymmetric endocytosis across the growth cone drives repulsive axon guidance
Association Membership(s) (4):
Society for Neuroscience, USA ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE JAPAN NEUROSCIENCE SOCIETY ,  日本生化学会
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