Habuchi Tomonori

ハブチトモノリ | Habuchi Tomonori

Affiliation and department：
Homepage URL (1)： http://www.med.akita-u.ac.jp/~hinyoki/default.html

Research field (1)： Urology

Research keywords (2)：泌尿器腹腔鏡手術 , 泌尿器科腫瘍学

Research theme for competitive and other funds (39)：

1991 - 2030 泌尿器科腫瘍学
1991 - 2030 Urologic Oncology
2021 - 2025 Molecular mechanisms and target molecules associated with progression and treatment resistance of urologic cancers associated with microbiome alterations by diet and obesity
2016 - 2021 Molecular analysis and delineation of the mechanisms underlying progression of urogenital cancers and alteration of tumor immuno-microenvironment associated with adiposity enhancement
2015 - 2020 Practical application of glycan-targeted biomarker to prevent over-diagnosis and over-treatment of prostate cancer

2015 - 2019 Mechanisms of B cell response after anti-CD20 antibody administration in immunogically-high risk kidney transplantation

2015 - 2018 Management of adverse effects of of androgen deprivation therapy in Japanese patients with prostate cancer

2014 - 2017 Identification of factors associated with drug-therapy resistance by pheripheral blood serum cell-free nucleotic acids

2013 - 2016 Molecular analysis and target exploration underlying progression of urologic cancers associated with obesity

2012 - 2015 Identification of molecules involved in progression of prostate cancer and construction of risk prediction model using SNP array

2010 - 2015 Development of glycan-targetted assay system for diagnosis of prostate cancer

2011 - 2013 Molecular Analysis of Rare Renal Cell Carcinoma and Identification of Molecular Therapeutic Targets

2011 - 2012 Clinical characteristics of Xp11.2 translocation renal cell carcinoma

2010 - 2012 Delineation of Molecular Mechanisms and Identification of Molecular Therapeutic Targets underlying Progression of Urologic Cancers Associated with High Fat or High Calorie Diet

2009 - 2011 Exploratory study of prognostic and therapeutic target moleculars in advanced prostate cancer

2007 - 2009 ELUCIDATION OF MOLECULAR MECHANISMS UNDERLINING THE PROGRESSION OF PROSTATE CANCER ASSOCIATED WITH HIGH-FAT DIET

2007 - 2009 膀胱がん好発モデルマウスを用いた治療標的分子の探索

2007 - 2008 Establishment of novel therapeutics for bladder cancer using nuclear acid medicine

2005 - 2006 Cavernous nerve regeneration by biodegradable alginate gel sponge sheet placement without sutures

2004 - 2006 Carbohydtare structure of prostate specific antigen (PSA)

2005 - 2005 遺伝子多型解析と動物モデルによる進行泌尿器癌の分子マーカーと標的分子の探索

2004 - 2005 Exploration for novel biologic markers which predict progression and prognosis of prostate cancer based on chromosomal alterations.

2004 - 2005 泌尿器癌を標的としたNIS遺伝子導入^<131>I放射線内照射療法の確立

2003 - 2005 IDENTIFICATION OF GENETIC FACTORS INFLUENCING THE RESPONSE TO MEDICAL THERAPY FOR UROLOGICA CANCERS

2002 - 2005 Development of Molecular Diagnostic System of Urological Tumors Using a Novel Program for Genetic Analysis

2003 - 2004 Analysis of IGF-I related gene polymorphisms and their impact on prostate cancer in Japanese population

2003 - 2004 Analysis of distribution of dihydrotestosterone concentration in prostate cancer tissue and differences of dihydrotestosterone and androgen induced gene expression after androgen deprivation

2003 - 2004 Functional and Expression Analyses of Endoplasmic Reticulum Stress Response Genes in Prostate Cancer

2003 - 2004 アンドロゲン依存性コレステロール合成系酵素DHCR24の前立腺癌における機能解析

2002 - 2003 肝細胞増殖因子(HGF)を用いた低コンプライアンス膀胱治療の研究

2002 - 2002 泌尿器科癌の発生リスクおよび治療反応性に関与する遺伝子多型に関する解析

2001 - 2002 前立腺癌のホルモン感受性を規定する患者サイドの遺伝因子の探索

2000 - 2001 The Clarification of Aberrant DNA Methylation at CpG sites in Age-related Urogenital Cancers

2000 - 2001 Changes in expression of neuroreceptor in unstable bladder and its functional role

2000 - 2001 腎癌発症におけるメチレーション異常の関与と背景因子の解明

1998 - 1999 Identification and Analysis of Candidate Tumor Suppressor Genes in Urothelial Cancer

1998 - 1999 A novel gene transfer method for prostate-specific and potent expression and its utilization in gene therapy

1998 - 1999 Study on prognostic factors for localized prostate cancer

1998 - 1999 Molecular chaperones in male infertility

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Papers (545)：

Mizuki Kobayashi, Kazuyuki Numakura, Shingo Hatakeyama, Toshiya Ishida, Atsushi Koizumi, Kazuki Tadachi, Ryoma Igarashi, Koichiro Takayama, Yumina Muto, Yuya Sekine, et al. Real clinical outcomes of nivolumab plus ipilimumab for renal cell carcinoma in patients over 75 years old. International journal of clinical oncology. 2023. 28. 11. 1530-1537
Kazuyuki Numakura, Mizuki Kobayashi, Yumina Muto, Hiromi Sato, Yuya Sekine, Ryuta Sobu, Yu Aoyama, Yoshiko Takahashi, Syuhei Okada, Hajime Sasagawa, et al. The Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer. Current oncology (Toronto, Ont.). 2023. 30. 9. 8092-8110
Kazuyuki Numakura, Yuya Sekine, Shingo Hatakeyama, Yumina Muto, Ryuta Sobu, Mizuki Kobayashi, Hajime Sasagawa, Soki Kashima, Ryohei Yamamto, Taketoshi Nara, et al. Primary resistance to nivolumab plus ipilimumab therapy in patients with metastatic renal cell carcinoma. Cancer medicine. 2023. 12. 16. 16837-16845
Takafumi Yanagisawa, Kenichi Hata, Shintaro Narita, Shingo Hatakeyama, Keiichiro Mori, Yuji Yata, Takayuki Sano, Takashi Otsuka, Shuhei Hara, Keiichiro Miyajima, et al. Docetaxel versus abiraterone for metastatic hormone-sensitive prostate cancer with focus on efficacy of sequential therapy. The Prostate. 2023. 83. 6. 563-571
Renpei Kato, Sei Naito, Kazuyuki Numakura, Shingo Hatakeyama, Tomoyuki Koguchi, Takahiro Kojima, Yoshihide Kawasaki, Shuya Kandori, Sadafumi Kawamura, Yoichi Arai, et al. Correction to: Significance of upfront cytoreductive nephrectomy stratified by IMDC risk for metastatic renal cell carcinoma in targeted therapy era - a multi-institutional retrospective study. International journal of clinical oncology. 2023. 28. 5. 726-727

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MISC (824)：

藤山信弘, 齋藤満, 山本竜平, 提箸隆一郎, 齋藤拓郎, 青山有, 沼倉一幸, 羽渕友則. 長期フォロー腎移植患者CNI血中濃度が与えるde novo DSA発生への影響. 日本腎臓病薬物療法学会誌. 2022. 11. 特別号. S162-S162
成田伸太郎, 齋藤満, 羽渕友則. 【新規保険収載ロボット支援手術手技を極める】ロボット支援腎尿管全摘除術. 泌尿器外科. 2022. 35. 9. 954-959
天野賢士, 嘉島相輝, 小泉淳, 南條博, 赤井太郎, 明円真吾, 安達尚宣, 川村貞文, 山本竜平, 奈良健平, et al. Carney複合に合併した難治性性索間質性腫瘍の1例. 泌尿器外科. 2022. 35. 9. 1021-1021
佐々木禎, 奈良健平, 小泉淳, 石田雅則, 青山有, 梶原知佳, 嘉島相輝, 山本竜平, 沼倉一幸, 齋藤満, et al. 診断に難渋したIVC浸潤を伴う腫瘍マーカー陰性NSGCTの1例. 泌尿器外科. 2022. 35. 9. 1022-1022
佐藤博美, 成田伸太郎, 石田雅宣, 高橋佳子, 黄明国, 嘉島相輝, 山本竜平, 小泉淳, 奈良健平, 沼倉一幸, et al. ラード食による前立腺癌発症・増殖における腸内細菌環境の解析(Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression). 日本癌学会総会記事. 2022. 81回. J-3038

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Books (3)：

泌尿器がんのすべて : 患者さんへの説明にそのまま使える!
メディカ出版 2013 ISBN:9784840443180
ベッドサイド泌尿器科学
南江堂 2013 ISBN:9784524250370
老化に伴う泌尿器癌発症におけるメチル化異常の病態解析
[羽渕友則] 2002

Education (2)：

1991 - Kyoto University Graduate School of Medicine
1980 - 1986 Kyoto University Faculty of Medicine

Professional career (1)：

医学博士 (京都大学)

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