Rchr
J-GLOBAL ID：200901095601049812   Update date: Apr. 07, 2024

Tsuzuki Shinobu

ツヅキ シノブ | Tsuzuki Shinobu
Affiliation and department：
Aichi Medical University School of Medicine

About Aichi Medical University School of Medicine


Job title： Laboratory Head
Research field  (1)： Hematology and oncology
Research keywords  (6)： がん遺伝子 ,  転写因子 ,  造血器腫瘍 ,  Oncogene ,  Transcription Factors ,  Hematological Malignancies
Research theme for competitive and other funds  (26)：
  • 2022 - 2026 隠れドライバーから見た、難治性リンパ性白血病の成立・維持機構の解明
  • 2020 - 2023 脂肪組織由来間葉系幹細胞-造血幹細胞における代謝経路解析:抗加齢作用に注目して
  • 2018 - 2021 Deciphering leukemia development and maintenance from the perspective of functions of fusion genes
  • 2015 - 2018 Investigation of mechanisms underlying the development of lymphoma and myeloma using a high-throughput mouse model system
  • 2010 - 2012 Investigation for molecular mechanisms underlying the establishment of "pre"-leukemic stem cells aiming for therapy and prevention of leukemia
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Papers (100)：
  • Sivasundaram Karnan, Ichiro Hanamura, Akinobu Ota, Lam Quang Vu, Kaori Uchino, Tomohiro Horio, Satsuki Murakami, Shohei Mizuno, Md Lutfur Rahman, Md Wahiduzzaman, et al. ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells. Cell death discovery. 2024. 10. 1. 56-56
  • Mina Noura, Hidemasa Matsuo, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa. Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia. Oncogene. 2023
  • Mina Noura, Takahiko Yasuda, Shinobu Tsuzuki, Hidemasa Matsuo, Hitoshi Kiyoi, Fumihiko Hayakawa. Suppression of Super-Enhancer-Driven TAL1 Expression By KLF4 in T-Cell Acute Lymphoblastic Leukemia. Blood. 2023. 142. Supplement 1. 1405-1405
  • Toshinori Hyodo, Eri Asano-Inami, Satoko Ito, Mai Sugiyama, Akihiro Nawa, Md Lutfur Rahman, Muhammad Nazmul Hasan, Yuko Mihara, Vu Quang Lam, Sivasundaram Karnan, et al. Leucine zipper protein 1 (LUZP1) regulates the constriction velocity of the contractile ring during cytokinesis. The FEBS Journal. 2023
  • Sivasundaram Karnan, Akinobu Ota, Hideki Murakami, Md. Lutfur Rahman, Md Wahiduzzaman, Muhammad Nazmul Hasan, Lam Quang Vu, Ichiro Hanamura, Akihito Inoko, Miho Riku, et al. CAMK2D: a novel molecular target for BAP1-deficient malignant mesothelioma. Cell Death Discovery. 2023
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MISC (59)：
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Patents (4)：
  • MEF2D融合型旧制リンパ性白血病を治療するための医薬組成物
  • MEF2D融合型旧制リンパ性白血病を治療するための医薬組成物
  • METHOD FOR DETERMINING PRESENCE OR ABSENCE OF SUFFERING FROM MALIGNANT LYMPHOMA OR LEUKEMIA, AND AGENT FOR TREATMENT AND/OR PREVENTION OF LEUKEMIA
  • 悪性リンパ腫又は白血病の罹患の有無の判定方法並びに白血病の治療及び/又は予防のための薬剤
Education (1)：
  • - 1987 Nagoya University School of Medicine
Professional career (1)：
  • Doctor of Medical Science (Nagoya University)
Work history (10)：
  • 2017/04 - 現在 Aichi Medical University School of Medicine Professor
  • 2016/07 - 2017/03 Aichi Medical University School of Medicine Associate Professor
  • 2005/04 - 2016/06 Aichi Cancer Center, Research Institute Chief Researcher
  • 2001/09 - 2005/03 Aichi Cancer Center, Research Institute Senior Researcher
  • 1998/11 - 2001/08 Institute of Cancer Research, UK
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Awards (1)：
  • 2004 - 日本白血病研究基金研究助成事業・一般研究賞
Association Membership(s) (4)：
米国血液学会 ,  日本内科学会 ,  日本血液学会 ,  日本癌学会
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