Rchr
J-GLOBAL ID：200901095766067130
Update date: Jan. 31, 2024
Hirano Tomoo
ヒラノ トモオ | Hirano Tomoo
Affiliation and department：
Job title：
Professor,Professor
Homepage URL (1)：
http://neurosci.biophys.kyoto-u.ac.jp/
Research field (2)：
Biophysics
, Neuroscience - general
Research keywords (4)：
生物物理学
, 神経科学一般
, Biophysics
, Neuroscience in General
Research theme for competitive and other funds (36)：
- 2018 - 2021 High spatiotemporal resolution analyses of dynamics of synaptic vesicle proteins
- 2017 - 2019 Input-shift mechanism for reflex eye movement by norepinephrine
- 2015 - 2018 Dynamics of glutamate receptor during synaptic plasticity
- 2013 - 2015 小脳抑制性シナプス可塑性の役割
- 2013 - 2015 シナプス後膜における受容体の局在・動態へのアミロイドβの作用
- 2011 - 2013 シナプス関連分子の機能解析を促進する新手法の開発
- 2009 - 2011 Single molecule analyses around the synaptic membrane formed on glass
- 2008 - 2009 グルタミン酸受容体デルタ2によるシナプス形成誘導
- 2006 - 2008 Regulation mechanism of information transmission at single central synapses
- 2006 - 2007 反射性眼球運動を用いるシナプス機能制御分子の生体でのはたらきの解析
- 2005 - 2005 ミュータントマウスと前庭動眼反射解析を用いた運動制御における機能分子の役割の検討
- 2000 - 2004 Molecular basis of motor learning dependent on the cerebellum
- 2000 - 2002 The Vestibular Ocular Reflex of the mutant mice deficient in delta 2 Glutamate receptor Subunit after unilateral labyrinthectomy
- 2000 - 2002 Induction and maintenance mechanism of late phase of cerebellar synaptic plasticity
- 1997 - 1998 Roles of specific glutamate receptor subunits in the cerebellar long-term depression
- 1995 - 1998 Search for gcncs rcgulating acuronal plasticity
- 1997 - 1997 グルタミン酸受容体サブユニット欠損ミュータントマウスの眼球運動解析
- 1996 - 1996 小脳プルキンエ細胞特異的グルタミン酸受容体欠損ミュータントマウスの運動学習
- 1996 - 1996 グルタミン酸受容体欠損ミュータントマウスの眼球運動解析
- 1996 - 1996 細胞外カリウムイオンにより誘導サレル膜電位依存性陽イオンチャネルの解析
- 1995 - 1996 Physiological studies on the mechanisms of synaptic transmission.
- 1995 - 1996 Molecular Basis of Sodium Channel Assembly in Neural Cells
- 1995 - 1995 培養小脳プルキンエ細胞における長期抑圧発現の分子機構
- 1993 - 1995 可塑性神経回路の情報処理
- 1994 - 1994 細胞部位選択的シナプス形成機構と伝達物質受容体の分布
- 1994 - 1994 シナプス伝達抑圧とグルタミン酸受容体
- 1993 - 1993 シナプス伝達抑圧とグルタミン酸受容体
- 1992 - 1993 Cell-site specific synapse formation in culture
- 1992 - 1992 培養下で構築した単純な神経回路モデルにおけるシナプス伝達調節
- 1989 - 1990 Local Application of Active Physiological Substances Using Laser, and Simultaneous Optical Recordings of Intracellular Ca^<++> Concentration and Membrane Potential
- 運動制御・運動学習機構
- シナプス形成機構
- シナプス伝達調節の細胞・分子機構
- Motor Control and Motor Learning
- Synapse formation
- Cellular and molecular mechanisms of synaptic modulation
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Papers (25)：
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Yuta Tezuka, Kenta M, Hagihara, Kenichi Ohki, Tomoo Hirano, Yoshiaki Tagawa. Developmental stage-specific spontaneous activity contributes to callosal axon projections. eLife. 2022. 11. e72435. 1-15
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Daria Merkurjev, Wan-Ting Hong, Kei Iida, Ikumi Oomoto, Belinda J. Goldie, Hitoshi Yamaguti, Takayuki Ohara, Shin-ya Kawaguchi, Tomoo Hirano, Kelsey C. Martin, et al. Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts. Nature Neuroscience. 2018. 1-11
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Fujii, S, Tanaka, H, Hirano, T. Suppression of AMPA receptor exocytosis contributes to hippocampal LTD. J. Neurosci. 2018. 38. 5523-5537
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Funahashi, J, Tanaka, H, Hirano, T. Visualization of synchronous or asynchronous release of single synaptic vesicle in active-zone-like membrane formed on neuroligin-coated glass surface. Frontiers in Cellular Neuroscience. 2018. 12. 140. 1-10
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Tomoo Hirano, Yoshito Yamazaki, Yoji Nakamura. LTD, RP, and Motor Learning. CEREBELLUM. 2016. 15. 1. 51-53
ｍore...
MISC (132)：
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Takuma Inoshita, Tomoo Hirano. Occurrence of long-term depression in the cerebellar flocculus during adaptation of optokinetic response. eLife. 2018. 7. e36209. 1-10
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Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Hum. Mol. Genet. 2018. 27. 18. 3165-3176
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Merkurjev, D, Hong, W. T, Iida, K, Oomoto, I, Goldie, B. J, Yamaguti, H, Ohara, T, Kawaguchi, S. Y, Hirano, T, et al. Synaptic m6A Epitranscriptome Reveals Functional Partitioning of Localized Transcripts for Dynamic Tripartite Synapse Modulation. Nature Neurosci. 2018. 21. 1004-1014
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Wakita, R, Tanabe, S, Tabei, K, Funaki, A, Inoshita, T, Hirano, T. Differential regulations of vestibulo-ocular reflex and optokinetic response by- and beta2-adrenergic receptors in the cerebellar flocculus. Scientific Reports. 2018. 7. 3944. 1-12
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Shumpei Fujii, Hiromitsu Tanaka, Tomoo Hirano. Detection and characterization of individual endocytosis of AMPA-type glutamate receptor around postsynaptic membrane. GENES TO CELLS. 2017. 22. 6. 583-590
ｍore...
Works (4)：
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小脳による学習機構についての包括的研究
2003 - 2008
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Comprehensive study on learning mechanism dependent on the cerebellum
2003 - 2008
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シナプス可塑性の分子機構と脳の制御機能、戦略的基礎研究
1997 - 2002
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Molecular mechanism of synaptic plaiticity and regulatory mechanism of brain
1997 - 2002
Education (4)：
- - 1985 The University of Tokyo
- - 1985 The University of Tokyo Graduate School, Division of Medical Sciences
- - 1979 The University of Tokyo Faculty of Science
- - 1979 The University of Tokyo Faculty of Science
Professional career (2)：
- Doctor of Medicine (The University of Tokyo)
- Doctor of Science (The University of Tokyo)
Work history (6)：
- 1991 - 1997 京都大学助教授
- 1991 - 1997 Kyoto University, Associate Professor
- 1988 - 1991 Gunma University
- 1988 - 1991 Gunma University, Lecturer
- 1985 - 1988 The University of Tokyo
- 1985 - 1988 University of Tokyo, Research Assistant
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Association Membership(s) (4)：
日本分子生物学会
, 北米神経科学会 (Society for Neuroscience)
, 日本神経科学学会
, 日本生理学会
