Research field (2):
Tumor diagnostics and therapeutics
, Fetal medicine/Pediatrics
Research keywords (3):
pediatric oncology
, 小児科学
, Pediatrics
Research theme for competitive and other funds (15):
2022 - 2025 The development of CAR-T therapy targeting FLT3 and CD19 for infant acute lymphoblastic leukemia
2021 - 2024 Liquid biopsy for Rhabdoid tumor by Exoxomal-microRNAs in blood and other body fluids
2019 - 2022 Development of CAR-T cell therapy for KMT2A-rearranged acute lymphoblastic leukemia
2017 - 2020 Mutations in the RAS Pathway as Potential Precision Medicine Targets in Treatment of Rhabdomyosarcoma
2016 - 2019 Elucidation of tumor immunity mechanism for clinical application of anti-PD1 antibody in childhood cancer
2014 - 2017 The establishment of peptide vaccine as a consolidation therapy for childhood cancer.
2014 - 2017 Study of recurrence mechanism in super high-risk neuroblastoma
2013 - 2016 The Epigenome Analysis of the Mechanisms of Chemoresistance and Development new treatment in Rhabdoid Tumor
2013 - 2016 Development of non-invasive diagnosis and novel therapies for pediatric solid tumor
2007 - 2009 molecular analyses and translational research of neuroblastoma based upon a clinical trial of the nation-wide group study
2007 - 2008 Impact of susteined expression of phox2b gene on the differentiation of neuroblastoma
2006 - 2007 EVALUATION OF PROGNOSIS AND EFFICACY OF THERAPY FOR NEUROBLASTOMA PATIENTS BY QUANTIFICATION OF METHYLATED DCR2 GENE PROMOTER IN SERUM DNA
2003 - 2005 神経芽腫担癌患児の血清中遊離DNAを用いた細胞遺伝子学的悪性度推定法の開発
神経芽細胞腫に関する研究
Study of Neuroblastoma
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Papers (217):
Akari Takai, Masaaki Yamagishi, Kazuyuki Ikeda, Atsuya Sugimoto, Eisuke Ichise, Yoshinobu Maeda, Satoshi Teramukai, Tatsuji Hasegawa, Shinichiro Oda, Tomoko Iehara. Effectiveness of cardiac palliative surgery for trisomy 18 patients with increased pulmonary blood flow. American journal of medical genetics. Part A. 2023. 191. 11. 2703-2710
Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda. Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors. Cancer medicine. 2023
MASAFUMI IGUCHI, SHIGEKI YAGYU, KOSUKE KAMBE, MAYUMI HIGASHI, SHIGEHISA FUMINO, TSUNAO KISHIDA, TOMOKO IEHARA, OSAM MAZDA, TATSURO TAJIRI. Development of anti-GD2 Antibody-producing Mesenchymal Stem Cells as Cellular Immunotherapy. Anticancer Research. 2023. 43. 6. 2417-2424
Kenji Okamoto, Toshihiko Imamura, Seiji Tanaka, Takayo Urata, Hideki Yoshida, Norio Shiba, Tomoko Iehara. The Nup98::Nsd1 fusion gene induces CD123 expression in 32D cells. International Journal of Hematology. 2023
Azusa Mayumi, Toshihiko Imamura, Hideki Yoshida, Shinya Osone, Takahiko Yasuda, Tomoko Iehara. Leukaemic cells expressing ETV6::FRK are sensitive to dasatinib in vivo. eJHaem. 2023