Rchr
J-GLOBAL ID：200901095933696625
Update date: Feb. 01, 2024
Suzuki Yuko
スズキ ユウコ | Suzuki Yuko
Affiliation and department：
Job title：
Chief Researcher
Research field (2)：
Experimental pathology
, Cell biology
Research keywords (10)：
stem cells
, ヒト多能性幹細胞
, 再生医学
, 治療
, 筋ジストロフィー
, 骨格筋
, cell transplantation
, regeneration
, muscular dystrophy
, skeletal muscle
Research theme for competitive and other funds (15)：
- 2022 - 2025 骨格筋組織幹細胞である筋衛星細胞におけるプロスタグランジンE2受容体の機能解析
- 2019 - 2022 Molecular mechanisms by which Notch regulates proliferation and differentiation of human muscle progenitors
- 2016 - 2019 application of induced mesenchymal stem cells from human iPS cells to cell therapy in muscular dystrophy
- 2013 - 2016 Elucidation of the mechanisms of skeletal muscle hypertrophy by intracellular calcium concentration.
- 2012 - 2015 Induction of transplantable myogenic cells from pluripotent stem cells
- 2011 - 2013 Determination of disease causing mechanisms of neuromyelitis optica by analyzing alpha1-syntrophin deficient mice
- 2008 - 2013 Cell therapy for muscular dystrophy
- 2009 - 2011 The elucidation of the molecular mechanisms of NO-mediated muscle atrophy
- 2008 - 2010 Study on molecular regulation of muscle regeneration by mesenchymal cells
- 2006 - 2008 Elucidation of molecular mechanisms of muscle atrophy,regeneration,hypertrophy and aging regulation.
- 2006 - 2007 Analysis of the roles of POMGnT1 in development and maintenance of certral nervous system and skeletal muscle
- 2004 - 2005 Analysis of roles for osteopontin in muscle regeneration
- 2003 - 2005 Elucidation of Molecular Mechanism of Muscle Regeneration of Dystrophin-dificient Duchenne Muscular Dystorophy
- 筋ジストロフィーの細胞治療
- 筋疾患に対する治療薬の創出を目指した研究
Show all
Papers (88)：
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Fusako Sakai-Takemura, Fumiaki Saito, Ken'ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Kiichiro Matsumura, Shin'ichi Takeda, Yoshitsugu Aoki, Yuko Miyagoe-Suzuki. Antioxidants restore store-operated Ca2+ entry in patient-iPSC-derived myotubes with tubular aggregate myopathy-associated Ile484ArgfsX21 STIM1 mutation via upregulation of binding immunoglobulin protein. FASEB bioAdvances. 2023. 5. 11. 453-469
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Fusako Sakai-Takemura, Fumiaki Saito, Ken'ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Kiichiro Matsumura, Shin'ichi Takeda, Yoshitsugu Aoki, Yuko Miyagoe-Suzuki. Antioxidants restore store-operated Ca2+ entry in patient-iPSC-derived myotubes with tubular aggregate myopathy-associated Ile484ArgfsX21 STIM1 mutation via upregulation of binding immunoglobulin protein. FASEB BioAdvances. 2023. 5. 11. 453-469
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Ahmed Elhussieny, Ken’ichiro Nogami, Fusako Sakai-Takemura, Yusuke Maruyama, Natsumi Takemura, Wael Talaat Soliman, Shin’ichi Takeda, Yuko Miyagoe-Suzuki. Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR). Stem Cell Research & Therapy. 2021. 12. 1
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Ken'ichiro Nogami, Yusuke Maruyama, Fusako Sakai-Takemura, Norio Motohashi, Ahmed Elhussieny, Michihiro Imamura, Satoshi Miyashita, Megumu Ogawa, Satoru Noguchi, Yuki Tamura, et al. Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx mice. Human Molecular Genetics. 2021. 30. 11. 1006-1019
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Naoki Ito, Yuko Miyagoe-Suzuki, Shin’ichi Takeda, Akira Kudo. Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration. International Journal of Molecular Sciences. 2021. 22. 7. 3627-3627
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MISC (62)：
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丸山友輔, 丸山友輔, 野上健一郎, 本橋紀夫, 竹村英子, 青木吉嗣, 内海文彰, 鈴木友子. プロスタグランジンE2受容体EP2は骨格筋幹細胞の維持に重要である. 日本薬学会関東支部大会講演要旨集. 2021. 65th (CD-ROM)
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丸山友輔, 丸山友輔, 野上健一郎, 本橋紀夫, 竹村英子, 内海文彰, 鈴木友子, 青木吉嗣. プロスタグランジンE2受容体EP2は筋衛星細胞の維持と自己複製を制御する. 日本筋学会学術集会プログラム・抄録集. 2021. 7th
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鈴木友子, 武田伸一. Duchenne型筋ジストロフィーの治療研究のUPDATES. 遺伝子医学. 2020. 10. 2. 48-54
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鈴木友子, 武田伸一. A.遺伝子の基礎 「遺伝子とは」. Clinical Neuroscience (月刊 臨床神経科学). 2020. 38. 3. 284-287
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野上健一郎, 丸山友輔, 竹村英子, 本橋紀夫, ELHUSSIENY Ahmed, 今村道博, 宮下聡, 小川恵, 野口悟, 三宅克也, et al. 筋小胞体カルシウムポンプSERCAの活性化による,Duchenne型筋ジストロフィーモデルマウスの病態改善. 日本筋学会学術集会プログラム・抄録集. 2020. 6th
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Patents (1)：
Books (9)：
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Mesenchymal Stem Cells for Regenerative Medicine for Duchenne Muscular Dystrophy
Intech 2020
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Muscle Cell and Tissue
2018
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Making skeletal muscle from human pluripotent stem cells.
2018
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Stem Cell-Based Therapy for Duchenne Muscular Dystrophy.
2016
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Translational Research in Muscular Dystrophy.
2016
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Lectures and oral presentations (71)：
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ヒト骨格筋前駆細胞の増殖と分化の制御機構の解明
(第18回日本再生医療学会総会 2019)
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ヒト骨格筋前駆細胞の増殖と分化の制御機構の解析
(第18回日本再生医療学会)
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ヒト人工多能性幹細胞から誘導される 骨格筋前駆細胞の増殖と分化制御機構の解析
(日本筋学会第4回学術集会)
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多能性幹細胞を用いた難治性筋疾患に対する細胞移植治療法の開発
(第17回日本再生医療学会総会 2018)
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ヒトiPS細胞を用いた難治性筋疾患に対する細胞移植治療法の開発.
(第39回国立精神・神経医療研究センター神経研究所 研究所発表会)
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Education (2)：
- - 1987 Kyushu University School of Medicine
- Kyushu University
Professional career (1)：
Association Membership(s) (3)：
日本筋学会
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, 日本分子生物学会
