Rchr
J-GLOBAL ID:200901096370363043
Update date: Feb. 01, 2024
Ikeda Yasuyuki
イケダ ヤスユキ | Ikeda Yasuyuki
Affiliation and department:
Research field (1):
Pathobiochemistry
Research keywords (1):
遺伝子変異 中性脂肪蓄積心筋血管症 脂肪細胞トリグリセリドリパーゼ 動脈硬化 肝性トリグリセリドリパーゼ リポ蛋白リパーゼ リポ蛋白代謝 高トリグリセライド血症 生活習慣病 Atherosclensis Hepatic triglyceride lipase Lipoprotein lipase Lipoprotein metabolism Hypertriglyceridema Life style-related deseases
Research theme for competitive and other funds (15):
- 2015 - 2018 Development of the prevention and early diagnosis system on atherosclerosis by using properties of multifunctional lipoprotein lipase
- 2009 - 2011 Development and the application of a comprehensive cause-analysis system for hypertriglyceridemia that is a risk factor for coronary heart disease
- 2008 - 2010 動脈硬化性疾患の発症に直結する新規バイオマーカーの発見と早期診断・治療法の開発
- 2005 - 2007 Development and application of “Catching-whole-mutations-in-genome method" that aims at health promotion activity
- 2004 - 2006 Establishment of genetic diagnostics, preventive and development of treatment for atherogenic hypertriglyceridemia
- 2002 - 2003 Establishment of an early diagnostic system for the detection of heart disease-related gene mutations with a novel electrochemical array chip
- 2000 - 2001 Development and application of DNA tip for the diagnosis of atherogenic hypertriglyceridemia
- 1999 - 2000 Establishment of personal protection method for life-style diseases : type IV hyperlipoproteinemia as a model case
- 1994 - 1995 Elucidation of an underlying etiology of atherogenic type IV hyperlipoproteinemia and development of its genetic diagnostic method
- 1994 - 1995 Molecular biological studies on the formation of atherogenic small dense low density lipoprotein (sLDL)
- 1993 - 1994 MOLECULAR-GENETIC STUDY OF FAMILIAR HYPERLIPOPROTEINEMIA RELATED TO ATHEROSCLEROSIS
- 1989 - 1990 Molecular Biological Study on Regulation and Expression of Physiological Function of Human Lipoprotein Lipase
- 1986 - 1989 Molecular Basis of the Etiology and Pathogenesis of Hyperlipoproteinemia
- 1986 - 1986 本態性高脂血症の成因,特に脂質水解酵素と関連因子の変異に関する分子遺伝学的研究
- 1986 - 1986 ヒト・リポ蛋白リパーゼの構造とその臓器特異性に関する研究
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Papers (34):
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Ming Li, Ken-Ichi Hirano, Yoshihiko Ikeda, Masahiro Higashi, Chikako Hashimoto, Bo Zhang, Junji Kozawa, Koichiro Sugimura, Hideyuki Miyauchi, Akira Suzuki, et al. Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder. Orphanet journal of rare diseases. 2019. 14. 1. 134-134
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Ken-ichi Hirano, Masahiro Higashi, Hideyuki Miyauchi, Atsuko Takagi, Yasuyuki Ikeda, Yusuke Nakano, Tetsuya Amano. Increased Washout of 123I-BMIPP in Triglyceride Deposit Cardiomyovasculopathy (TGCV) with Severe Coronary Stenosis. Annals of Nuclear Cardiology. 2019. 5. 1. 47-49
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Sawa Minohara, Sung Kwan Bae, Saori Sugiyama, Noriko Shibata, Toshifumi Gushima, Junichi Motoshita, Shinji Shimoda, Atsuko Takagi, Yasuyuki Ikeda, Kazuhiro Takahashi. A case of non-alcoholic steatohepatitis complicated with severe acute pancreatitis induced by decreased lipoprotein lipase and hepatic triglyceride lipase activity levels in a young Japanese woman. Clinical case reports. 2018. 6. 9. 1769-1773
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Akira Suzuki, Satoshi Yamaguchi, Ming Li, Yasuhiro Hara, Hideyuki Miyauchi, Yoshihiko Ikeda, Bo Zhang, Masahiro Higashi, Yasuyuki Ikeda, Atsuko Takagi, et al. Tricaprin Rescues Myocardial Abnormality in a Mouse Model of Triglyceride Deposit Cardiomyovasculopathy. Journal of oleo science. 2018. 67. 8. 983-989
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Atsuko Takagi, Yasuyuki Ikeda, Kunihisa Kobayashi, Kazuhiro Kobayashi, Yoshihiko Ikeda, Junji Kozawa, Hideyuki Miyauchi, Ming Li, Chikako Hashimoto, Yasuhiro Hara, et al. Newly developed selective immunoinactivation assay revealed reduction in adipose triglyceride lipase activity in peripheral leucocytes from patients with idiopathic triglyceride deposit cardiomyovasculopathy. Biochemical and biophysical research communications. 2018. 495. 1. 646-651
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MISC (56):
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原康洋, 平野賢一, 山口知是, 鈴木朗, 高木敦子, 池田康行, 恩田弘明, 川崎直子, 足立淳, 朝長毅. 中性脂肪蓄積心筋血管症(TGCV)患者線維芽細胞を用いた細胞内Triglyceride蓄積機構の解析. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2017. 49th. 298 (WEB ONLY)-298
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橋本 千佳子, 鈴木 朗, 高木 敦子, シュレスタ・ロジート, 中林 十士紀, 李 銘, 池田 康行, 惠 淑萍, 和田 晃, 平野 賢一. 中鎖脂肪酸療法が著効を示した特発性中性脂肪蓄積心筋血管症の一例. 日本動脈硬化学会総会プログラム・抄録集. 2017. 49回. 297-297
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平野 賢一, 安井 洋子, 東 将浩, 坂口 学, 鈴木 朗, 高木 敦子, Shrestha Rojeet, 橋本 千佳子, 李 銘, 原 康洋, et al. 中鎖脂肪酸療法により難治性狭心症が改善した特発性中性脂肪蓄積心筋血管症の一例. 日本動脈硬化学会総会プログラム・抄録集. 2017. 49回. 241-241
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Y. Ikeda, A. Takagi, N. Iwai, Y. Kokubo, H. Tomoike. ENVIRONMENTAL RISK FACTORS LEADING TO HYPERTRIGLYCERIDEMIA ON HETEROZYGOUS LIPOPROTEIN LIPASE (LPL) DEFICIENCY IDENTIFIED IN THE GENERAL POPULATION OF JAPANESE. ATHEROSCLEROSIS SUPPLEMENTS. 2010. 11. 2. 81-81
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Analysis of lipoprotein lipase and hepatic triglyceride lipase activities, immunoreactive masses and genes. Japanese journal of clinical medicine. 2009. 67. 443-450
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Patents (3):
Professional career (1):
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