Rchr
J-GLOBAL ID：200901096620548338   Update date: Jan. 30, 2024

Okada Motoi

オカダ モトイ | Okada Motoi
Affiliation and department：
Asahikawa Medical University Department of Emergency Medicine

About Asahikawa Medical University Department of Emergency Medicine


Job title： Professor
Other affiliations (1)：
  • University of Cincinnati/Cardiovascular Center  Research Scientist
Research field  (4)： Emergency medicine ,  Cardiology ,  Cell biology ,  Molecular biology
Research keywords  (2)： 心不全 ,  血管再生
Research theme for competitive and other funds  (5)：
  • 2021 - 2024 The role of beta-3 receptors and sphingosine 1-phosphate in the regulation of myocardial metabolism in sepsis
  • 2018 - 2022 Elucidation of myocardial energy metabolism via beta-3 receptor in sepsis
  • 2015 - 2018 敗血症の予後予測因子とβ遮断薬の有効性と機序の解明
  • 2010 - 2013 障害血管リモデリングおよび血管外膜微小血管新生における神経再生因子の役割
  • 2010 - 2013 骨髄由来内皮前駆細胞におけるプロスタノイドの包括的役割解明
Papers (13)：
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MISC (26)：
  • Motoi Okada, Satoshi Kawaguchi, Yuta Kashiwagi, Kentaro Hayashi, Satoshi Fujita, Naoyuki Hasebe. Carvedilol Improves Prognosis in Sepsis-induced Cardiomyopathy Through the Activation of "telomere-p53-pgc Signaling". CIRCULATION. 2016. 134
  • Hideyuki Kondo, Ha Won Kim, Lei Wang, Motoi Okada, Ronald W. Millard, Tohru Masuyama, Yigang Wang. Blockade of Senescence-associated Microrna-195 in Aged Skeletal Myoblasts Facilitates Reprogramming to Produce Induced Pluripotent Stem Cells. CIRCULATION. 2015. 132
  • Motoi Okada, Hawon Kim, Muhammad Ashraf, Jun-ichi Kawabe, Naoyuki Hasebe. Abrogation of miR-195 Improves Function in Aged Heart by Preventing Telomere Shortening and Mitochondrial Dysfunction. CIRCULATION. 2014. 130
  • Ha Won Kim, Motoi Okada, Kaoru Matsu-ura, Muhammad Ashraf. Resetting Aging Clock in the Senescent Stem Cells by Suppressing Microrna-146a Promotes Cardiomyogenesis in the Ischemic Heart. CIRCULATION. 2013. 128. 22
  • Sanjay Kumar, Motoi Okada, Dehua Chang, Muhammad Ashraf. A Novel Phosphorylating Mechanism of STAT3 in Protection against Ischemia/reperfusion by Pharmacological Preconditioning With Tadalafil, a PDE Inhibitor. CIRCULATION. 2013. 128. 22
ｍore...
Lectures and oral presentations  (9)：
  • Transcriptional Repression of Protein Kinase G during Ischemic-Reperfusion Injury in Stem Cells is Restored by Inhibition of Phosphodiesterase 5A with Long Acting Tadalafil
    (AHA 2012)
  • Senescence-Associated microRNA-146a Suppresses Cardiomyogenic Potential by Targeting Notch1: Insights from Small Juvenile Stem Cells
    (AHA 2012)
  • Rejuvenation of Aged Bone Marrow Stem Cells with Microrna-195 for Cardiac Repair
    (AHA 2012)
  • Mitochondrial Transgenic Expression of Connexin 43 Confers Cytoprotection to he Stem Cells and Cardiomyocytes in Ischemic Myocardium
    (AHA 2011)
  • Existence of Small Juvenile Cells in the Aging Bone Marrow Stromal Cells and Their Therapeutic Potential for Ischemic Heart Disease
    (AHA 2011)
ｍore...
Education (1)：
  • - 1992 Jichi Medical University
Professional career (1)：
  • 医学博士 (旭川医科大学)
Awards (1)：
  • 2015/09 - ESC Best Poster Award
Association Membership(s) (5)：
THE JAPAN SOCIETY OF ULTRASONICS IN MEDICINE ,  American Heart Assocition ,  JAPANESE ASSOCIATION FOR ACUTE MEDICINE ,  JAPANESE CIRCULATION SOCIETY ,  THE JANPANESE SOCIETY OF INTERNAL MEDICINE
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