Research theme for competitive and other funds (27):
2023 - 2028 Science for Boundary Lubrication - Essence of Low Friction Mechanism Based on Structure and Dynamics of Additive Adsorption Layer
2021 - 2024 深海模倣系構築による高圧下の蛋白質構造の実測法の開発
2020 - 2023 分子混雑環境下におけるクリスタリンの構造解析
2019 - 2023 量子ビーム相関解析法による生体高分子構造・ダイナミクスの探求
2018 - 2023 ヌクレオソーム高次構造とダイナミクスの解析によるクロマチン潜在能の解明
2018 - 2023 Neutron Structural Biology for New Generation
2018 - 2019 細胞再現系での蛋白質の構造・ダイナミクスの解明
2016 - 2018 量子ビーム散乱法の協奏的利用による機能性ヌクレオソームの溶液構造解析
2016 - 2018 巨大タンパク質会合体における動的ネットワークとその機能解明
2015 - 2018 Mechanism of sugar chain elongation catalyzed by muscular dystrophy cause gene product LARGE
2015 - 2018 Development of Analysis Method for Reconbinant Biomacromolecular System utlizing Neutron Scattering
2014 - 2016 CV-SANS法による変異型ヌクレオソームの詳細構造解析
2014 - 2016 生体分子集合体が形成する動的平衡の中性子小角散乱による研究
2014 - 2016 Formation of nanostructure of food plant proteins
2012 - 2015 Development of analysis method for dynamic state in high order structure of protein utilizing neutron scattering
2012 - 2014 重水素化中性子小角散乱を用いた天然変性タンパク質による揺らぎ構造の解析
2011 - 2014 Development of fabrication technique for a two-dimensional neutron focusing mirror and the performance test
2008 - 2012 Mechanism of abnormal protein aggregation and the study of the repair enzyme.
2009 - 2011 Analysis for Dynamics on High Order Structure of Protein
1999 - 2010 ソフトマターの構造研究
1999 - 2010 Structural Investigation on Soft Matter
2007 - 2008 Study on Mechanism of Formation of High-Order Structure of Protein
2007 - 2008 Studies on structures and electric field effects in liquid crystalline soft matters
2006 - 2008 Structural study of Parkinson disease related protein by intermediate region neutron scattering method
2004 - 2005 ヘテロ高分子の構造転移に伴う疎水性水和水の動的構造の変化
2001 - 2002 ACカロリメーター比熱測定による生体高分子の協同的立体構造変調の研究
1996 - 1996 中性子小角散乱法による多糖類電解質高分子のゾル-ゲル転移の観測
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Papers (206):
Masahiro Nishimura, Takeru Fujii, Hiroki Tanaka, Kazumitsu Maehara, Ken Morishima, Masahiro Shimizu, Yuki Kobayashi, Kayo Nozawa, Yoshimasa Takizawa, Masaaki Sugiyama, et al. Genome-wide mapping and cryo-EM structural analyses of the overlapping tri-nucleosome composed of hexasome-hexasome-octasome moieties. Communications Biology. 2024. 7. 1
Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki, Yuki Fujii, Shaymaa Mohamed Mohamed Badawy, Ken Morishima, Aya Okuda, Rintaro Inoue, Masaaki Sugiyama, Eri Chatani. Mechanistic modeling of amyloid oligomer and protofibril formation in bovine insulin. Journal of Molecular Biology. 2024. 168461-168461
Rintaro Inoue, Tomotaka Oroguchi, Takashi Oda, Bela Farago, Anne Martel, Lionel Porcar, Mamoru Sato, Masaaki Sugiyama. Internal dynamics of multidomain protein as revealed by an optimized neutron spin echo measurement and all-atom molecular dynamics simulation. Physical Review Research. 2023. 5. 4
Hisashi Ishida, Atsushi Matsumoto, Hiroki Tanaka, Aya Okuda, Ken Morishima, Paul A Wade, Hitoshi Kurumizaka, Masaaki Sugiyama, Hidetoshi Kono. Structural and Dynamical Changes of Nucleosome upon GATA3 Binding. Journal of molecular biology. 2023. 168308-168308
Toshiyuki Chatake, Yasuhide Yanagisawa, Risa Murakami, Tadanori Ohsugi, Hiroyuki Sumi, Takumi Takata, Aya Okuda, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama. Characterization of K-binding factor involved in water-soluble complex of menaquinone-7 produced by Bacillus subtilis natto. The Journal of Biochemistry. 2023
中川洋, 斎尾智英, 長尾道弘, 長尾道弘, 長尾道弘, 井上倫太郎, 杉山正明, 富永大輝, 川北至信. Analysisi of Hierarchy of Structure and Dynamics of Multidomain Proteins. 量子ビームサイエンスフェスタ(Web). 2022. 2021
柚木康弘, 松本淳, 守島健, MARTEL Anne, PORCAR Lionel, 佐藤信浩, 與語理那, 與語理那, 與語理那, 富永大輝, et al. The Advantage of Small-angle Neutron Scattering Revealed through Analyzing the Overall Structure of a Fully Assembled Complex in Circadian Clock. 波紋. 2022. 32. 4