Watanabe Takashi

ワタナベタカシ | Watanabe Takashi

Affiliation and department：
Homepage URL (1)： https://www.fujita-hu.ac.jp/faculty/medicine/department/biochemistry.html

Research field (4)： Tumor biology , Medical biochemistry , Cell biology , Molecular biology

Research keywords (13)： Tumour heterogeneity , cancer stem cell , optogenetics , imaging , シグナル伝達 , 細胞骨格 , 細胞極性 , structure , signal transduction , cytoskeleton , membrane , small GTPases , cell polarity

Research theme for competitive and other funds (8)：

2023 - 2026 脳腫瘍における治療抵抗性がん細胞の多様性の解析とその克服戦略の勘案
2020 - 2023 がん幹細胞のリン酸化シグナルの解析による治療標的分子の探索
2019 - 2021 S100 protein in metastasis and dormancy of breast cancer stem cell
2013 - 2016 Elucidation of phosphorylation signal regulating the cell polarity
2008 - 2012 MOLECULAR MECHANISMS UNDERLYING CELL POLARIZATION IN MIGRATING CELLS AND NEURONS

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Papers (45)：

Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Munetsuna E, Watanabe T, Kono S, Okada S, Suzuki M, et al. Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction. 2021. 13. 16. 4238
Hisano Yanagi, Takashi Watanabe, Tatsunori Nishimura, Takanori Hayashi, Seishi Kono, Hitomi Tsuchida, Munetsugu Hirata, Yuko Kijima, Shintaro Takao, Seiji Okada, et al. Upregulation of S100A10 in metastasized breast cancer stem cells. Cancer science. 2020. 111. 12. 4359-4370
柳久乃, 渡辺崇, 西村建徳, 林孝典, 岡田誠治, 鈴木元, 南博信, 鈴木聡, 河田健司, 後藤典子, et al. 転移乳がん幹細胞におけるS100A10の発現上昇. 日本癌学会総会記事. 2020. 79回. PJ11-1
Yasuhiro Funahashi, Takashi Watanabe, Kozo Kaibuchi. Advances in defining signaling networks for the establishment of neuronal polarity. Current opinion in cell biology. 2020. 63. 76-87
Junko Mukohyama, Taichi Isobe, Qingjiang Hu, Takanori Hayashi, Takashi Watanabe, Masao Maeda, Hisano Yanagi, Xin Qian, Kimihiro Yamashita, Hironobu Minami, et al. miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells. Cancer research. 2019. 79. 20. 5151-5158

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MISC (14)：

T. Watanabe, K. Matsuzawa, S. Wang, T. Matsui, M. Kakeno, K. Kaibuchi. Regulation of the Rac activator Tiam1 by aPKC phosphorylation. MOLECULAR BIOLOGY OF THE CELL. 2012. 23
Keiko Yokoi, Takashi Watanabe, Tomoki Nishioka, Kenji Matuzawa, Shujie Wang, Kazuhide Sato, Mai Kakeno, Toshinori Matsui, Kozo Kaibuchi. Identification and characterization of RacGEF (Tiam1) interactors. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 168P-168P
Norimichi Itoh, Takashi Watanabe, Kozo Kaibuchi. Par3 regulates directional migration through CALSP2. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 257P-257P
Takumi Harada, Jun Noritake, Takashi Watanabe, Shujie Wang, Toshinori Matsui, Norimichi Itoh, Masaki Fukata, Kozo Kaibuchi. Phosphorylation of CLASP2 by GSK-3 regulates the interaction with IQGAP1. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2007. 103. 160P-160P
Watanabe T, Noritake J, Wang S, Harada T, Kaibuchi K. [Motility of fibroblast cells and its regulatory mechanisms]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2006. 51. 6 Suppl. 715-720

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Education (3)：

2001 - 2005 名古屋大学大学院医学系研究科
1999 - 2001 名古屋大学大学院生命農学研究科
1995 - 1999 Nagoya University School of Agricultural Sciences Department of Applied Biological Sciences

Professional career (1)：

Ph.D. (Nagoya University)

Work history (4)：

2019/02 - 現在 Fujita Health University Medical School Associate Professor
2014/02 - 2019/01 University of North Carolina at Chapel Hill School of Medicine Associate professor
2011/04 - 2014/01 Nagoya University Graduate School of Medicine, Division,Center for Neural Disease and Cancer,Graduate School of Medicine,Nagoya University Graduate School of Medicine, Division,Center for Neural Disease and Cancer,Graduate School of Medicine,Nagoya University Designated lecturer
2007/05 - 2011/03 Nagoya University Designated lecturer

Association Membership(s) (1)：

日本癌学会

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