Rchr
J-GLOBAL ID：200901097983809652
Update date: Mar. 05, 2024
Tamura Jun-ichi
タムラ ジュンイチ | Tamura Jun-ichi
Affiliation and department：
Research field (3)：
Applied molecular and cellular biology
, Bioorganic chemistry
, Molecular biochemistry
Research keywords (2)：
糖鎖合成化学
, Chemistry of Saccharide Synthesis
Research theme for competitive and other funds (17)：
- 2023 - 2026 ホルモンと糖鎖から解き明かす骨格筋間質の機能維持機構
- 2019 - 2024 Biology of sugar-alcohol modification in glycan
- 2020 - 2023 脂肪細胞分化抑制活性を示すコンドロイチン硫酸種の同定と機能の解明・脂肪量の制御
- 2018 - 2021 Understanding of the mechanism of ribitol-phosphate modification and application of its physiological function to therapy
- 2015 - 2019 Synthetic study of bypass-like glycans as therapeutic agent for muscular dystrophy
- 2014 - 2017 Identification and clarification of chondroitin sulfate subtype which controls skeletal muscle differentiation
- 2011 - 2016 Regulatory mechanisms of neuronal activity by chondroitin sulfate chains
- 2011 - 2016 Deciphering sugar chain-based signals regulating integrative neuronal functions
- 2010 - 2012 Identification and functional analysis of chondroitin sulfatesinvolved in sizing and development of eye
- 2008 - 2010 Development of diagnostic technology for cancer detection using FRET and heparanase specificity
- 2003 - 2005 磁性ナノ粒子を用いる新しい有機固相合成法の開発
- 2002 - 2004 Development of oligosaccharide conjugates that could be potentially utilized as vaccines against pathogenic Gram-negative bacteria
- 2000 - 2002 Study on the mechanism of molecular recognition between the glycosyl transferase and the core-peptide controlling heparin biosynthesis
- 1998 - 2000 Development of pseudo-LOS vaccines
- 1997 - 1998 生理活性糖類・硫酸化グリコサミノグリカンの構造と生合成に関する研究
- 生理活性オリゴ糖鎖の合成研究
- Synthetic Study on Bioactive Oligosaccharides
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Papers (32)：
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Danang Dwi Cahyadi, Katsuhiko Warita, Naoko Takeda-Okuda, Jun-Ichi Tamura, Yoshinao Z Hosaka. Qualitative and quantitative analyses in sulfated glycosaminoglycans, chondroitin sulfate/dermatan sulfate, during 3 T3-L1 adipocytes differentiation. Animal science journal = Nihon chikusan Gakkaiho. 2023. 94. 1. e13894
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Toshiyasu Koike, Tadahisa Mikami, Jun-Ichi Tamura, Hiroshi Kitagawa. Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia. Nature Communications. 2022. 13. 1
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Jun-ichi Tamura, Takahiro Tamura, Shunsuke Hoshino, Rieko Imae, Ryuichi Kato, Mizuki Yokono, Mao Nagase, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi, et al. Chemical and Chemo-Enzymatic Syntheses of Glycans Containing Ribitol Phosphate Scaffolding of Matriglycan. ACS Chemical Biology. 2022. 17. 6. 1513-1523
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Satomi Nadanaka, Jun-ichi Tamura, Hiroshi Kitagawa. Chondroitin Sulfates Control Invasiveness of the Basal-Like Breast Cancer Cell Line MDA-MB-231 Through ROR1. Frontiers in Oncology. 2022. 12. 914838
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Danang Dwi Cahyadi, Munehiro Okamoto, Katsuhiko Warita, Naoko Takeda-Okuda, Jun-Ichi Tamura, Yoshinao Z Hosaka. Compositional analysis of chondroitin/dermatan sulfate in rhesus monkeys (Macaca mulatta). Bioscience, biotechnology, and biochemistry. 2022. 86. 7. 811-818
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MISC (76)：
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Takahiro Tamura, Yuka Omura, Jun-ichi Tamura. Stereo- and Regioselective Synthesis of O-Mannosyl Glycan Containing Matriglycan and a Part of Tandem Ribitol Phosphate. The Journal of Organic Chemistry. 2020
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武田(奥田)尚子, YEON Su-Jung, 保坂善真, 田村純一. Analytical study on chondroitin sulfate and dermatan sulfate in the cartilaginous tissues and internal organs of wild sika deer. 日本糖質学会年会要旨集. 2020. 39th
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Miharu Shida, Tadahisa Mikami, Jun-ichi Tamura, Hiroshi Kitagawa. Chondroitin sulfate-D promotes neurite outgrowth by acting as an extracellular ligand for neuronal integrin αVβ3. Biochimica et Biophysica Acta (BBA) - General Subjects. 2019. 1863. 9. 1319-1331
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Kazuma Sakamoto, Tomoya Ozaki, Yen-Chun Ko, Cheng-Fang Tsai, Yuanhao Gong, Masayoshi Morozumi, Yoshimoto Ishikawa, Kenji Uchimura, Satomi Nadanaka, Hiroshi Kitagawa, et al. Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis. Nature Chemical Biology. 2019. 15. 7. 699-709
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Naoko Takeda-Okuda, Shuji Mizumoto, Zui Zhang, Soo-Ki Kim, Chi-Ho Lee, Byong-Tae Jeon, Yoshinao Z. Hosaka, Kenji Kadomatsu, Shuhei Yamada, Jun-ichi Tamura. Compositional analysis of the glycosaminoglycan family in velvet antlers of Sika deer (Cervus nippon) at different growing stages. Glycoconjugate Journal. 2019. 36. 2. 127-139
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Patents (6)：
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リン酸化三糖セリン,硫酸化、リン酸化三糖セリンおよびそれらの合成方法
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硫酸化、リン酸化三糖セリンの製造に有用な脱離基としてトリクロロアセトイミデートを持つ糖供与体,その製法およびその中間
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オリゴ糖合成にかかる繰り返し二糖とそのオリゴマーの製造法
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天然高分子化合物の抽出・精製システム
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オリゴグリコサミノグリカンの製造方法、並びに還元末端グルクロン酸型オリゴコンドロイチン硫酸、及びこれを含む医薬組成物
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Books (5)：
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Oligosaccharides in Chemistry and Biology: A Comprehensive Handbook
Wiley/ VCH 2000
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Oligosaccharides in Chemistry and Biology: A Comprehensive Handbook
Wiley/ VCH 2000
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Oligosaccharides in Chemistry and Biology : A Comprehensive Handbook, Vol. (]G0001[) : Synthesis of Oligosaccharides, Glycoconjugates and Glyco mimetics, Part 1 : Glycosylation Methods : Chapter 8 : Alkylations of Reducing Sugars
Wiley-VCH 2000
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生物化学実験法42「生理活性糖鎖研究法」
学会出版センター 1999
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Experimental Method of Biological Chemistry, 42 Methods in Bio-active Carbohydrates
Japan Scientific Societies Press, Tokyo 1999
Works (4)：
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Synthetic Studies on glycosyl Ligand for nanomolecules
2000 - 2003
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プロテオグリカン分子の設計と合成
1996 - 2003
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ナノ粒子用糖質配位子の合成に関する研究
2000 - 2001
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Design and Synthesis of Proteoglycans
1996 - 2001
Education (2)：
- - 1989 Tokyo Institute of Technology Interdisciplinary Science and Engineering
- - 1989 Tokyo Institute of Technology Graduate School, Division of Integrated Science and Engineering
Professional career (1)：
- (BLANK) (Tokyo Institute of Technology)
Work history (6)：
- 1993 - 1995 理化学研究所基礎科学特別 研究員
- 1993 - 1995 RIKEN, Basic Science Program Award
- 1991 - 1992 アレクサンダー・フォン・フンボルト財団 奨学生
- 1991 - 1992 Alexander von Humboldt Foundation, Research Fellow
- 1989 - 1991 Nihon University College of Humanities and Sciences
- 1989 - 1991 Nihon University, Research Assistant
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Committee career (2)：
- 2001 - 現在 日本農芸化学会 中四国支部評議員
- 2001 - 現在 日本糖質学会 評議員
Awards (2)：
- 2002 - (社)有機合成化学協会 帝人研究企画賞
- 2002 - Teijin Award in Synthetic Organic Chemistry, Japan
Association Membership(s) (5)：
Society for glycobiology
, 日本化学会
, 日本農芸化学会
, 有機合成化学協会
, 日本糖質学会
