Rchr
J-GLOBAL ID:200901098356723412
Update date: Feb. 01, 2024
Fujita Hiroyoshi
フジタ ヒロヨシ | Fujita Hiroyoshi
Affiliation and department:
Job title:
特任教授
Homepage URL (1):
http://babu.med.hokudai.ac.jp/~hyg-w/
Research field (4):
Medical biochemistry
, Healthcare management, medical sociology
, Hygiene and public health (laboratory)
, Pathobiochemistry
Research keywords (4):
衛生学
, 環境医学
, 分子病態学
, 環境応答
Research theme for competitive and other funds (36):
- 2020 - 2023 中皮腫に対する細胞治療の実現を目指して
- 2017 - 2020 Tracing Japanese donor families from brain-dead donor in Japan from bioethics and medical anthroplogy views
- 2014 - 2017 Roles of innate immune cells in opportunistic infections
- 2014 - 2017 Retransplantation from brain death and organ transplant from Bioethic and Medical anthropological views
- 2010 - 2013 Protection against Asbestosis.
- 2011 - 2012 Development of new protective method against environmental factors.
- 2010 - 2012 Development of evaluation methods for effects of environmental chemicals on the central nervous systems
- 2009 - 2011 Elucidation of roles of essential trace metals in higher nervous activity
- 2007 - 2008 ストレスの定量的評価の試み
- 2005 - 2006 ヒトは環境変動をどうとらえているのか?-環境検知機構の解明と応用の試み-
- 2003 - 2005 Elucidation of the mechanism of membrane transport, metallochaperone of essential trace metals related to central nervous activities
- 2001 - 2005 Tolerance induction by gene therapy in organ transplantation
- 2003 - 2004 Discovery of protein-to-protein interactions in platelets by a novel methods.
- 2003 - 2004 作用機構の解明に直結する微量化学物質による次世代影響評価法の開発-中枢神経系の構築に対する多角的影響評価を中心として-
- 2002 - 2004 Regulation of transcription by heme with sperm reference to cell differentiation
- 2001 - 2003 Evaluation of toxicities of porphyrin derivatives and its possible application
- 2001 - 2001 重金属中毒学のパラダイムシフト
- 2000 - 2001 最先端医療の医療技術評価
- 2000 - 2000 先天性鉄代謝病態にかかわる遺伝子多型の遺伝性ポルフィリン症発症への影響の解明
- 1998 - 2000 Molecular Mechanisms Involved in Oxygen Sensing by Heme.
- 1997 - 1998 生命の適応戦略:ヘムの機能の考案
- 1996 - 1997 Molecular Mechanisms for delta-Aminolevulinate Synthase Gene
- 1995 - 1997 Molecular Mechanism of Erythroid Differentiation
- 1996 - 1996 化学物質毒性発現のモニタリング法の開発
- 1995 - 1995 ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制
- 1995 - 1995 環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみ
- 1994 - 1995 ヘム合成酵素におけるスプライシング異常と赤血球分化との関係
- 1994 - 1994 ヒト ヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構
- 1994 - 1994 環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみ
- 1993 - 1994 Molecular analyzes of heme regulation and its disorders.
- 1993 - 1994 Expression of delta-aminolevulinate synthase durin erythroid differentiation
- 1993 - 1993 ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構
- 1985 - 1985 有害物質のδ-アミノレブリン酸脱水酵素生合成に与える影響の研究
- 1983 - 1983 鉛によるδアミノレブリン酸脱水酵素の合成誘導機構の研究
- 1976 - 環境因子への生物応答の分子機構
- 1976 - Stress reaction against environment
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Papers (32):
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Chie Sugimoto, Hiroyoshi Fujita, Hiroshi Wakao. Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy. Biomedicines. 2022. 10. 12
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Chie Sugimoto, Yukie Murakami, Eisuke Ishii, Hiroyoshi Fujita, Hiroshi Wakao. Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity. eLife. 2022. 11
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Ishikawa M, Iriyama N, Tokuhira M, Takaku T, Sato E, Sugimoto KJ, Nakazato T, Fujita H, Kimura Y, Fujioka I, et al. Potential role for second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia harboring additional clonal chromosome abnormalities: A retrospective CML Cooperative Study Group analysis. Oncology reports. 2019. 42. 6. 2836-2843
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Iriyama N, Tokuhira M, Sato E, Sugimoto KJ, Takaku T, Ishikawa M, Nakazato T, Fujita H, Kimura Y, Fujioka I, et al. Smoking influences the outcomes of patients receiving tyrosine kinase inhibitors for chronic myeloid leukemia in the chronic phase: A retrospective analysis. Hematological oncology. 2019. 37. 3. 323-325
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Iriyama N, Sugimoto KJ, Sato E, Takaku T, Tokuhira M, Nakazato T, Ishikawa M, Fujita H, Fujioka I, Kimura Y, et al. Comparison of the clinical outcomes of nilotinib and dasatinib therapies in newly diagnosed patients in the chronic phase of chronic myeloid leukemia: a retrospective analysis. Medical oncology (Northwood, London, England). 2018. 35. 11. 142-142
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MISC (112):
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I. Fujioka, T. Takaku, N. Iriyama, M. Tokuhira, E. Sato, M. Ishikawa, T. Nakazato, K-J. Sugimoto, H. Fujita, N. Asou, et al. ANALYSIS OF VASCULAR ADVERSE EVENTS IN TKI TREATED JAPANESE CML PATIENTS: RETROSPECTIVE LARGE COHORT STUDY OF CML COOPERATIVE STUDY GROUP. HAEMATOLOGICA. 2017. 102. 435-436
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若尾宏, 杉本智恵, 藤田博美. CRISPRを利用したヒトiPS細胞のゲノム編集による細胞傷害分子の可視化. 日本衛生学雑誌. 2015. 70. Supplement
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Constitutively active Stat5A and Stat5B promote adipogenesis. 2012. 87. 6. 281-281
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Makoto Watanabe, Akio Koyama, Takeshi Saito, Kouich Terasawa, Hiroyoshi Fujita, Kazuo Saito. [Dr Leonor Michaelis and early days of Hokkaido University School of Medicine; episodes among three medical researchers in the roaring twenties]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. 2011. 86. 4-5. 203-8
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Hiroshi Wakao, Rika Wakao, Atsushi Oda, Hiroyoshi Fujita. Constitutively active Stat5A and Stat5B promote adipogenesis. Environmental health and preventive medicine. 2011. 16. 4. 247-52
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Patents (1):
Books (26):
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衛生・公衆衛生学
アイ・ケイコーポレーション 2018 ISBN:9784874923566
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サクシュコトニ川原の落書 : 藤田博美教授退職記念文集
北海道大学医学部社会医学講座衛生学・細胞予防医学分野 2015
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改訂版分子予防環境医学
本の泉社 2010
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生化学基礎の基礎(韓国語版)
化学同人 2009
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ヘムによる転写調節機構と造血細胞分化に果たす役割の解明
[北海道大学大学院医学研究科] 2005
more...
Works (2):
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環境から生命へ、生命から環境へ、第71回日本衛生学会総会フォーラム、「21世紀の環境医学へ:我々はどのように適応してきたか?」
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鉛中毒をモデルとして、シンポジウム「重金属中独学のパラダイムシフト」
Education (2):
- 1976 - 1980 Kyoto University Graduate School Division of Medicine
- 1970 - 1976 Kyoto University Faculty of Medicine Department of Medical Science
Professional career (1):
Work history (9):
- 2015/12 - 現在 Dokkyo Medical University Lab. Hematology and Oncology Adjunct Professor
- 2015/04 - 現在 北海道大学 名誉教授
- 1999/04 - 2015/03 Hokkaido University School of Medicine Lab. Environmental Biology Professor
- 1998/09 - 1999/03 Hokkaido University School of Medicine Department of Hygiene Professor
- 1997/04 - 1998/08 Tohoku University School of Medicine Lab. Molecular Biology Associate Professor
- 1991/09 - 1997/03 Tohoku University School Of Medicine Department of Applied physiology and Molecular Biology Associate Professor
- 1990/07 - 1991/09 The Rockefeller University Lab. Biochemical Hematology Assistant Professor
- 1985/09 - 1990/06 The Rockefeller University Lab. Metabolism and Pharmacology Research Associate
- 1981/09 - 1985/08 Tohoku University School of Medicine Department of Hygiene and Environmental Health Research Associate
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Committee career (7):
Awards (1):
- 1996/01 - 東北医学会 医学奨学賞金賞 ヘム代謝調節の分子機構
Association Membership(s) (7):
米国血液学会
, 米国生化学会
, (社)環境科学会
, 日本生化学会
, 日本衛生学会
, American Society of Hematology
, American Society for Biochemistry and Molecular Biology
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