Art

J-GLOBAL ID：200902076485851877   Reference number：86A0463141

Immunosuppression by captopril in vitro: Inhibition of human natural killer activity by copper-dependent generation of hydrogen peroxide.

in vitroにおけるカプトプリルによる免疫抑制 銅依存性の過酸化水素生成によるヒトナチュラルキラー活性の抑制

Author (6)： SUGIYAMA E (Toyama Medical and Pharmaceutical Univ.) ,  IWATA M (Toyama Medical and Pharmaceutical Univ.) ,  YAMASHITA N (Toyama Medical and Pharmaceutical Univ.) ,  YOSHIKAWA T (Toyama Medical and Pharmaceutical Univ.) ,  MARUYAMA M (Toyama Medical and Pharmaceutical Univ.) ,  YANO S (Toyama Medical and Pharmaceutical Univ.)
Material： Japanese Journal of Medicine  (Jpn J Med)
Volume： 25  Issue： 2  Page： 149-154  Publication year： May. 1986 
JST Material Number： Z0157B  ISSN： 0021-5120  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： proline ,...

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JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Basic research of vasoactive drugs and hypotensive drugs  (GW07040J)

Reference (29)：

• 1) Atkinson AB, Brown JJ, Fraser R, et al: Captopril in hypertension with renal artery stenosis and intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensin I and II and aldosterone and in body composition. Clin Sci 57: 139, 1979.
• 2) Atkinson AB, Robertson JIS: Captopril in the treatment of clinical hypertension and cardiac failure. Lancet 2: 836, 1979.
• 3) Wilkin JK, Hammond JJ, Kirkendall WM: The captopril-induced eruption. Arch Dermatol 116: 902, 1980.
• 4) Amann FW, Buhler FR, Cozen D, et al: Captopril associated agranulocytosis. Lancet 1:150, 1980.
• 5) Hoorntje SJ, Kallenberg CGM, Weening JJ, et al: Immune complex glomerulopathy in patients treated with captopril. Lancet 1: 1212, 1980.

Terms in the title (7)： カプトプリル ,  免疫抑制 ,  銅 ,  依存性 ,  過酸化水素 ,  ヒト ,  ナチュラルキラー活性