The Chromosome 7 Annotation Project

• The Centre for Applied Genomics

The Chromosome 7 Annotation Project is a database that contains descriptive information of human chromosome 7. It is fully sequenced and annotated with medically relevant data. Chromosome 7 houses genes related to more than 360 diseases and disorders e.g. cystic fibrosis, Russell-Silver syndrome and Williams-Beuren syndrome. It is also believed that chromosome 7 carries loci for a number of neuropsychiatric diseases e.g. autism, alcoholism, bipolar affective disorder, panic disorder and schizophrenia. Although it has not yet been identified, cytogenetic evidence suggests that chromosome 7 carries a gene that causes cancer. The database provides access to a table of clinical breakpoints in chromosome 7 as well as a comprehensive list of other tables containing genetic information about this chromosome. Keyword and Blast search options are available. Even the families of diseased patients may search the database for information by selecting a link called 'Family Village'.