Art

J-GLOBAL ID：201702224593166818   Reference number：17A0019052

膵管癌におけるWnt/β-catenin経路の新たな標的遺伝子の探索

Author (1)： SANO MAKOTO (日本大 医 病態病理学系 人体病理学分野)
Material： 日本膵臓病研究財団研究報告書  (Annual Report. Pancreas Research Foundation of Japan)
Volume： 23rd  Page： 99-101  Publication year： Dec. 20, 2016 
JST Material Number： F1487A  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Cyr61 ,...

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JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Clinical oncology in general  (GE03010Y)

Reference (5)：

• Zhu L, Shi G, Schmidt CM, Hruban RH, Konieczny SF (2007) Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia. Am J Pathol 171: 263-273.
• Bardeesy N, DePinho RA (2002) Pancreatic cancer biology and genetics. Nat Rev Cancer 2:897-909.
• Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA (2003) Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4:437-450.
• Sano M, Driscoll DR, DeJesus-Monge WE, Klimstra DS, Lewis BC (2014) Activated Wnt Signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms. Gastroenterology 146(1):257-267. doi:10.1053/ j.gastro.2013.09.044.
• Sano M, Driscoll DR, DeJesus-Monge WE, Quattrochi B, Appleman VA, Ou J, Zhu LJ, Yoshida N, Yamazaki S, Takayama T, Sugitani M, Nemoto N, Klimstra DS, Lewis BC; Activation of Wnt/β-catenin signaling enhances pancreatic cancer development and the malignant potential via upregulation of Cyr61/CCN1. Neoplasia,in press.

Terms in the title (5)： 膵管癌 ,  Wnt ,  経路 ,  標的遺伝子 ,  探索