Art

J-GLOBAL ID：201702224832751473   Reference number：17A0292827

Flavonoid from Scutellaria stems and leaves attenuates composited Aβ-induced memory impairment and apoptosis in rats

【結語】:バイカリンは,AΒによって誘発されたラットの記憶障害を軽減し,神経細胞のアポトーシスを阻害する。【JST・京大機械翻訳】

Author (8)： Cheng Jianjun (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Zhao Hongxiang (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Guo Ke (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Miao Hong (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Ma Shuai (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Gao Yang (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Wang Xiaoqing (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College) ,  Shang Yazhen (Hebei Provincial Key Research Office of Traditional Chinese Medicine Against Dementia,Hebei Provincial Key Laboratory of Traditional Chinese Medicine Research and Development,Institute of Traditional Chinese Medicine,Chengde Medical College)
Material： Zhongguo Xinyao Zazhi  (Chinese Journal of New Drugs)
Volume： 25  Issue： 22  Page： 2627-2636  Publication year： 2016 
JST Material Number： C2251A  ISSN： 1003-3734  Document type： Article
Article type： 原著論文  Country of issue： China (CHN)  Language： CHINESE (ZH)

Abstract/Point： Objective: To investigate the ...

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Thesaurus term： cytosol ,  human(primates) ,  *neuron ,  Bax protein ,  RT-PCR ,  Western blotting ,  *apoptosis ,  mitochondria ,  mitochondrial membrane ,  intracerebral administration ,  screening(inspection) ,  *memory disorder
Semi thesaurus term： カスパーゼ9 ,  BCL-2 ,  水迷路試験 , 【Automatic Indexing@JST】

Author keywords (6)： flavonoid from Scutellaria stems and leaves (SSF) ,  β-amyloid protein 25-35 ,  aluminum trichloride ,  recombinant human transforming growth factor β 1 ,  memory ,  apoptosis

JST classification (4)： Basic neurology  (GN01020W) ,  Central nervous system  (EJ12030F) ,  Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic research of other drugs acting on central nervous system  (GW03120U)

Terms in the title (7)： バイカリン ,  誘発 ,  ラット ,  記憶障害 ,  神経細胞 ,  アポトーシス ,  阻害