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J-GLOBAL ID:201702248495254615   Reference number:17A0461644

Pharmacokinetic Problems with Psychotropic Drug Combination Therapy

向精神薬の多剤・大量療法からの脱却への道-清く正しく美しく-向精神薬併用療法の薬物動態学的問題点
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Volume: 119  Issue:Page: 180-184  Publication year: Mar. 25, 2017 
JST Material Number: Z0692A  ISSN: 0033-2658  Document type: Article
Article type: 解説  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Clinical biopharmacy  ,  Drugs acting on central nervous system in general 
Reference (8):
  • 藤井康男: ゼプリオン投与中の死亡例から,我々は何を学ぶべきか? 精神経誌, 117; 132-145, 2015
  • 加藤隆一: 臨床薬物動態学-臨床薬理学・薬物療法の基礎として-改訂第4版. 南江堂, 東京, 2011
  • Ozdemir, V., Naranjo, C. A., Herrmann, N., et al. : Paroxetine potentiates the central nervous system side effects of perphenazine : contribution of cytochrome P4502D6 inhibition in vivo. Clin Pharmacol Ther, 62 ; 334-347,1997
  • Saito, M., Yasui-Furukori, N., Nakagami, T., et al. : Dose-dependent interaction of paroxetine with risperidone in schizophrenic patients. J. Clin Psychopharmacol, 25 ; 527-532,2005
  • Spina, E., Avenoso, A., Salemi, M., et al. : Plasma concentrations of clozapine and its major metabolites during combined treatment with paroxetine or sertraline. Pharmacopsychiatry, 33 ; 213-217,2000
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