Art
J-GLOBAL ID：201702256507607031   Reference number：17A0104409

Hydroxytriptolide (LLDT-8) Inhibits Inflammatory Cytokines and Promotes Apoptosis in Human Rheumatoid Arthritis Fibroblast-like Synoviocytes by TNF-α Induced via Ras-MAPKs Signaling Pathway

雷藤舒はTNF-Αによって誘導されるヒトリウマチ関節炎滑膜線維芽細胞のアポトーシス、抗炎症及びRAS-MAPKSシグナル伝達経路に対する調節作用を有する。【JST・京大機械翻訳】
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Author (7)：
Wang Rongsheng

About Wang Rongsheng

(Shanghai University of Traditional Chinese Medicine)

About Shanghai University of Traditional Chinese Medicine

, 
Liu Jia

About Liu Jia

(Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital)

About Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital

, 
Tong Ping

About Tong Ping

(Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital)

About Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital

, 
He Shijun

About He Shijun

(Shanghai Institute of Materia Medica,Chinese Academy of Sciences)

About Shanghai Institute of Materia Medica,Chinese Academy of Sciences

, 
Wu Yanwei

About Wu Yanwei

(Shanghai Institute of Materia Medica,Chinese Academy of Sciences)

About Shanghai Institute of Materia Medica,Chinese Academy of Sciences

, 
Zuo Jianpin

About Zuo Jianpin

(Shanghai Institute of Materia Medica,Chinese Academy of Sciences)

About Shanghai Institute of Materia Medica,Chinese Academy of Sciences

, 
He Dongyi

About He Dongyi

(Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital)

About Department of Rheumatology,Guanghua Integrative Chinese & Western Medicine Hospital


Material：
Shanghai Zhongyiyao Daxue Xuebao  (Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai)

About Shanghai Zhongyiyao Daxue Xuebao


Volume： 30  Issue： 3  Page： 82-87  Publication year： 2016 
JST Material Number： C3148A  ISSN： 1008-861X  Document type： Article
Article type： 原著論文  Country of issue： China (CHN)  Language： CHINESE (ZH)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
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Objective: To observe the effe...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
anti-inflammatory action

About anti-inflammatory action

, 
TUNEL method

About TUNEL method

, 
TNF

About TNF

, 
coculture

About coculture

, 
*apoptosis

About apoptosis

, 
*synovial membrane

About synovial membrane

, 
RT-PCR

About RT-PCR

, 
*human(primates)

About human(primates)

, 
Western blotting

About Western blotting

, 
interleukin 6

About interleukin 6

, 
phosphorylation

About phosphorylation


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
滑膜細胞

About 滑膜細胞

, 
蛋白質発現

About 蛋白質発現

, 
マトリックスメタロプロテイナーゼ3

About マトリックスメタロプロテイナーゼ3

, 
*滑膜線維芽細胞

About 滑膜線維芽細胞

, 【Automatic Indexing@JST】
Author keywords (6)：
LLDT-8

About LLDT-8

, 
tumor necrosis factor alpha

About tumor necrosis factor alpha

, 
rheumatoid arthritis

About rheumatoid arthritis

, 
synovial fibroblast

About synovial fibroblast

, 
ras-MAPKs signaling pathway

About ras-MAPKs signaling pathway

, 
in vitro

About in vitro

JST classification (2)：
JST classification
Category name(code) classified by JST.
Basic research of anti-inflammatory drugs 
(GW15010T)

About Basic research of anti-inflammatory drugs

,  Cell physiology in general 
(EF02010S)

About Cell physiology in general

Terms in the title (9)：
Terms in the title
Keywords automatically extracted from the title.
雷

About 雷

, 
誘導

About 誘導

, 
ヒト

About ヒト

, 
リウマチ関節炎

About リウマチ関節炎

, 
滑膜線維芽細胞

About 滑膜線維芽細胞

, 
アポトーシス

About アポトーシス

, 
抗炎症

About 抗炎症

, 
シグナル伝達経路

About シグナル伝達経路

, 
調節

About 調節


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