Art

J-GLOBAL ID：201702274701478490   Reference number：17A0136571

Metallothioneins are required for human basophil interleukin-4 gene induction via FcεRΙ stimulation

メタロチオネインはFcεRΙ刺激を介したヒト好塩基球インターロイキン-4遺伝子誘導に必要である

Author (5)： Ugajin Tsukasa (Department of Dermatology, Graduate School, Tokyo Medical and Dental University) ,  Shibama Sayaka (Department of Dermatology, Graduate School, Tokyo Medical and Dental University) ,  Nishida Keigo (Laboratory for Homeostatic Network, RIKEN Research Center for Integrative Medical Sciences (IMS)) ,  Nishida Keigo (Laboratory of Immune Regulation, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science) ,  Yokozeki Hiroo (Department of Dermatology, Graduate School, Tokyo Medical and Dental University)
Material： Allergology International  (Allergol Int)
Volume： 65  Issue： 4  Page： 466-468(J-STAGE)  Publication year： 2016 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *metallothionein ,...
Semi thesaurus term： Fc epsilon RI

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A0136571&from=J-GLOBAL&jstjournalNo=L6446A") }}

JST classification (1)： Biological function  (EB03040U)

Reference (10)：

• 1. Thirumoorthy N, Manisenthil Kumar KT, Shyam Sundar A, Panayappan L, Chatterjee M. Metallothionein: an overview. World J Gastroenterol 2007;13:933-6.
• 2. Schroeder JT, MacGlashan Jr DW, Lichtenstein LM. Human basophils: mediator release and cytokine production. Adv Immunol 2001;77:93-122.
• 3. Yoshimoto T, Yasuda K, Tanaka H, Nakahira M, Imai Y, Fujimori Y, et al. Baso- phils contribute to T(H)2-IgE responses in vivo via IL-4 production and presen- tation of peptide-MHC class II complexes to CD4+ T cells. Nat Immunol 2009;10:706-12.
• 4. Motomura Y, Morita H, Moro K, Nakae S, Artis D, Endo TA, et al. Basophil- derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. Immunity 2014;40:758-71.
• 5. Egawa M, Mukai K, Yoshikawa S, Iki M, Mukaida N, Kawano Y, et al. Inflamma-tory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4. Immunity 2013;38:570-80.

Terms in the title (7)： メタロチオネイン ,  刺激 ,  ヒト ,  好塩基球 ,  インターロイキン-4 ,  遺伝子 ,  誘導