Rchr

J-GLOBAL ID：201001087790410502 Update date: Apr. 17, 2024

Takuya Shimazaki

シマザキタクヤ | Takuya Shimazaki

Affiliation and department：
Job title： Associate Professor

Research field (2)： Developmental biology , Neuroscience - general

Research keywords (3)： Central Nervous System Regeneration , Neural Stem Cell , Neural Development

Research theme for competitive and other funds (10)：

2019 - 2021 Transcription factors regulating temporal specification of neuronal subtypes.
2018 - 2021 Regulatory mechanisms of aging of adult neural stem/progenitor cells via p38 MAPK
2015 - 2018 Mechanisms of glial development
2010 - 2016 Generation of Neural Diversity and Neocortex
2010 - 2015 Mechanisms of neurogenesis and gliogenesis by neural stem cells

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Papers (78)：

Kase Y, Kase Y, Shimazaki T, Okano H. Current understanding of adult neurogenesis in the mammalian brain: How does adult neurogenesis decrease with age?. Inflammation and Regeneration. 2020. 40. 1
Kase Y, Otsu K, Shimazaki T, Okano H. Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling. Stem Cell Reports. 2019. 12. 6. 1313-1328
Takuya Shimazaki. Vertebrate neural stem cells: Development, plasticity, and regeneration. Keio Journal of Medicine. 2016. 65. 1. 1-15
HSHIMAZAKI TAKUYA, HR. Heterochronic microRNAs in temporal specification of neural stem cells: application toward rejuvenation. NPJ Aging and Mechanisms of Diseases. 2016. 2. 15014
Jun Tsuyama, Jens Bunt, Linda J. Richards, Hiroko Iwanari, Yasuhiro Mochizuki, Takao Hamakubo, Takuya Shimazaki, Hideyuki Okano. MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells. STEM CELL REPORTS. 2015. 5. 3. 365-377

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MISC (18)：

金田勇人, 島崎琢也, 岡野栄之. 臨床応用を目指した基礎研究体細胞研究神経幹細胞分化の制御機構. 日本臨床. 2015. 73. 204-209
金田勇人, 島崎琢也, 岡野栄之. 分化誘導と分化転換 10.神経幹細胞の時系列的な分化能の変化とそのメカニズム. 実験医学. 2015. 33. 2. 273-278
金田勇人, 馬渕洋, 大石路子, 中村志穂, 山路智也, 松崎有未, 島崎琢也, 岡野栄之. 組織幹細胞に共通する老化メカニズムの解析と制御法の開発. 再生医療. 2014. 13. 240
金田勇人, 中村志穂, 島崎琢也, 岡野栄之. 神経幹細胞のコンピテンスの制御. 日本分子生物学会年会プログラム・要旨集(Web). 2012. 35th. 4P-0487 (WEB ONLY)
HAYAKAWA YANO Yoshika, SHIMAZAKI Takuya, OKANO Hideyuki. Regulation of neural progenitor proliferation by EGF signaling in the spinal cord. Inflammation and regeneration. 2008. 28. 5. 447-453

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Lectures and oral presentations (41)：

ES細胞を利用した神経再生の可能性
(第3回日本再生医療学会総会・シンポジウム 2004)
骨髄由来の神経幹細胞選択的nestin遺伝子発現細胞
(第3回日本再生医療学会総会 2004)
神経幹細胞の分化に及ぼす外傷性脳損傷後の炎症性サイトカインの影響
(第27回日本神経外傷学会 2004)
O3K-8 Galectin-1is a key regulator of Neural Stem Cell proliferation
(第26回日本分子生物学会年会 2003)
Downregulation of STAT3 activation contiributes to triggering the differentiation of presumptive rod photoreceptor cells
(第26回日本分子生物学会年会 2003)

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Professional career (1)：

博士(医学) (東京大学大学院医学系研究科)

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