Rchr
J-GLOBAL ID：201101006541992671
Update date: Mar. 14, 2024
Tochitani Shiro
Tochitani Shiro | Tochitani Shiro
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://nrid.nii.ac.jp/nrid/1000090418591/
Research field (9)：
Fetal medicine/Pediatrics
, Neuroscience - general
, Obstetrics and gynecology
, Physiology
, Psychiatry
, Food sciences
, Anatomy
, Hygiene and public health (non-laboratory)
, Hygiene and public health (laboratory)
Research keywords (19)：
maternal gut microbiota
, mother-infant interaction
, brain-gut interaction
, postnatal brain development
, 神経前駆細胞
, 細胞分化
, cortical laminar formation
, behavioral analyses
, mother milk, breast milk
, GABA_A受容体
, stress
, gut microbiome
, 大脳皮質
, microglia
, neural stem cell
, 細胞分裂
, GABA
, エタノール
, 催奇形性
Research theme for competitive and other funds (13)：
- 2023 - 2026 母体腸内細菌叢撹乱がもたらす周産期母体変化の機序と子の神経発達アウトカムの解明
- 2020 - 2023 Elucidation of the basic physiological condition that the healthy maternal microbiota prepares for the normal brain development of the offspring.
- 2018 - 2022 高齢者健康寿命延伸を可能にする栄養-腸内細菌叢-多臓器健全連関の分子機序解明
- 2017 - 2020 肝吸虫による胆管癌についてのメコン川流域と中国西江流域の分子疫学的比較研究
- 2018 - 2019 周産期メンタルウェルビーイングを目標とする腸内細菌叢の介入法の確立
- 2018 - 2019 周産期母親の養育行動における腸内細菌の機能の解明
- 2017 - 2019 腸内細菌撹乱マウスの母乳解析に基づく仔の脳発達を促進する物質の網羅的探索
- 2017 - 2018 マウス周産期母体腸内細菌撹乱モデルの有効性の検討
- 2014 - 2017 Analyses on the mechanisms underlying the perturbation of regulatory machinery of intrinsic cellular properties of neural progenitors by the suppressed level of maternally-derived taurine
- 2015 - 2016 Analyses on the functions of maternal gut microbiota in the development of fetal and neonatal central nervous system
- 2014 - 2015 Analyses on the functions of the intestinal microbiota of pregnant mothers in the development of fetal and neonatal central nervous system
- 2011 - 2012 Analyses on the mechanisms of the teratogenic effectsof GABAA receptor-targeting drugs by way of the perturbation of the regulation of the cellular properties of neural progenitor cells
- 2009 - 2010 The mechanistic analyses on the effects of ethano Ion the maturation and the differentiation of neural stem cells in the primordium of cerebral cortex.
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Papers (33)：
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Shiro Tochitani. Pivotal Roles of Maternal Gut Microbiota in Child Development: Vertical Microbial Transmission and Perinatal Mental Health. Jap J Stress Sci. 2024. 38. 2. 413-425
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Naoya Nakagawa, Tomoyuki Enokiya, Shiro Tochitani, Maki Nakahigashi, Keigo Nishida, Kazuya Ooi, Shosuke Kawanishi, Nagayasu Toyoda. Effects of Zinc Supplementation in the Elderly with Focus on Muscle Mass, Dry Skin, and Gut Microbiota. BPB Reports. 2023. 6. 6. 217-225
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Stress-control of perinatal mothers from the view point of gut microbiota. Microbiome Science. 2023. 10. 2. 194-199
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栃谷 史郎. 子どもの脳発達の基盤となる周産期母体腸内細菌. 食と医療. 2023. 24. 14-20
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Shiro Tochitani. Taurine: A Maternally Derived Nutrient Linking Mother and Offspring. Metabolites. 2022. 12. 3. 228-228
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MISC (5)：
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栃谷 史郎. ひとつの腸由来代謝物が宿主の脳活動と不安様行動を変容させる. Microbiome Science. 2023. 2. 2. 49-50
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栃谷 史郎, 塚原 隆充, 松崎 秀夫, 井上 亮. マウス周産期母体腸内細菌叢の撹乱は仔の腸内細菌叢の定着に影響を与える. 腸内細菌学雑誌. 2017. 31. 2. 124-124
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栃谷 史郎, 古川 智範, 伊藤 崇志, 小島 俊男, 松崎 秀夫, 福田 敦夫. 発生期マウス大脳皮質においてタウリンは神経前駆細胞の時系列的性質変化を制御する. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [2P1332]-[2P1332]
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栃谷 史郎, 古川 智範, 伊藤 崇志, 小島 俊男, 松崎 秀夫, 福田 敦夫. 発生期マウス大脳皮質においてタウリンは神経前駆細胞の時系列的性質変化を制御する. 日本脳科学会プログラム・抄録集. 2015. 42回. 21-21
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Shiro Tochitani, Shigeaki Kondo, Hiromi Sakata-Haga, Yoshihiro Fukui. Neurogenesis is regulated by the signals via GABAA receptors in the neural progenitors in the developing cortex. NEUROSCIENCE RESEARCH. 2011. 71. E124-E125
Patents (2)：
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妊娠期母体腸内細菌攪乱による行動異常モデル動物の作製方法とその用途
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自閉症スペクトラム障害モデル動物ならびにその作製方法および用途
Books (8)：
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精神医学領域の論文を読みこなすキーワード100!
株式会社 新興医学出版社 2023 ISBN:9784880028866
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食品免疫学事典
朝倉書店 2021 ISBN:9784254431261
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Frontiers in gut microbiota research
2021
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ヒトマイクロバイオーム Vo. 2
(株)エヌ・ティー・エス 2020
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医療人の基礎知識 第3版
三重大学出版会 2020
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Lectures and oral presentations (50)：
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母体腸内細菌叢と子の神経発達
(日本発達神経科学学会第12回学術集会 シンポジウム3「腸内細菌と脳発達」 2023)
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撹乱された母体腸内細菌叢のプロファイルを仔は継承する
(第11回日本DOHaD学会学術集会 2023)
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Maternal gut microbiota confering a basis for healthy brain development of offspring
(The 39th annual meeting of the Japanese Association of Stress Sciences 2023)
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Administration of human milk oligosaccharides during the early postnatal period ameliorates the behavioral alteration of offspring in a mouse model of perturbed maternal gut microbiota.
(22nd International Congress of Nutrition 2022)
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周産期母体腸内細菌叢撹乱は母体生理・代謝に様々な変容をもたらす
(第10回日本DOHaD学会学術集会 2022)
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Education (2)：
- 1997 - 2001 The Graduate University for Advanced Studies School of Life Science
- 1995 - 1997 東京大学大学院 理学系研究科 生命科学専攻 修士課程
Professional career (2)：
- PhD (The Graduate University for Advanced Studies)
- Master of Science (The University of Tokyo)
Work history (13)：
- 2023/04 - 現在 Suzuka University of Medical Science Faculty of Health Science Professor
- 2018/04 - 現在 Suzuka University of Medical Science Division of Health Science, Graduate School of Health Science Associate professor
- 2017/08 - 現在 Hamamatsu University School of Medicine Faculty of Medicine
- 2017/04 - 現在 Chiba University visiting researcher
- 2017/04 - 2023/03 Suzuka University of Medical Science Faculty of Health Science Associate professor
- 2017/04 - 2020/03 University of Fukui Center for Child Mental Development visiting associate professor
- 2013/12 - 2017/03 Osaka University Osaka University, Kanazawa University, Hamamatsu Graduate School of Medicine, Chiba University, University of Fukui, United Graduate School of Child Mental Development Assistant Professor
- 2013/10 - 2017/03 University of Fukui
- 2008/10 - 2013/09 The University of Tokushima Faculty of Medicine
- 2008/07 - 2008/09 Musashino University Faculty of Pharmacy Visiting professor
- 2008/04 - 2008/06 RIKEN
- 2004/12 - 2008/03 RIKEN
- 2003/01 - 2004/11 MIT The Picower Center for Learning and Memory Postdoctoral researcher
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Committee career (3)：
- 2022/07 - 現在 Microbiome Science 編集委員
- 2022/07 - 現在 日本DOHaD学会 代議員
- 2017/04 - 2018/03 機能性農産物活用促進協議会 会員
Awards (3)：
- 2021/03 - 鈴鹿医療科学大学 学生授業評価高得点賞
- 2016/07 - The Japan Society for Developmental Origins of Health and Disiease Best Poster Award at the fifth annual meeting of the Japan Society for Developmental Origins of Health and Disease
- 2009/03 - 徳島大学医学部 ベストティーチャーオブザイヤー2008
Association Membership(s) (8)：
JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
, 日本DOHaD学会
, 日本腸内細菌学会
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
, The Society for Neuroscience
, THE JAPANESE ASSOCIATION OF ANATOMISTS
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPAN NEUROSCIENCE SOCIETY
