Yamazaki Masatoshi

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Nagano Hospital Cardiology President, Director of Cardiology

Homepage URL (2)： http://www.bmpe.t.u-tokyo.ac.jp/index.html , http://www.bmpe.t.u-tokyo.ac.jp/en/index.html

Research field (4)： Biomedical engineering , Cardiology , Clinical pharmacy , Physiology

Research keywords (5)： Computer simulation , Ventricular Fibrillation , Atrial Fibrillation , Optical Mapping , Arrhythmia

Research theme for competitive and other funds (15)：

2021 - 2024 位相分散解析と不整脈の臨床的可視化手法の統合による慢性心房細動の多元的治療戦略
2020 - 2023 神経型ナトリウムチャネルを標的とする新しい抗不整脈薬開発のための基盤研究
2019 - 2022 Atrial Fibrillation Suppression and Electrophysiological Mechanisms of Heavy Ion Beam in Pathological Rabbits
2018 - 2021 Novel therapeutic strategies for ventricular fibrillation as a mechanism of 3-dimensional scroll wave with filament.
2018 - 2021 Development of Strategic Control Technology Based on Phase Variance Analysis for Pathophysiology, Diagnosis, and Treatment of Intractable Arrhythmias

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Papers (88)：

富井直輝, 稲田慎, 芦原貴司, 山崎正俊, 瀬野宏, 佐久間一郎, 中沢一雄. Feasibility Study of Phase Variance Analysis on Three-dimensional Atrial Fibrillation Model(タイトル和訳中). 日本循環器学会学術集会抄録集. 2023. 87回. PJ101-6
Mari Amino, Masatoshi Yamazaki, Koichiro Yoshioka, Noboru Kawabe, Sachie Tanaka, Takashi Shimokawa, Ryoko Niwa, Naoki Tomii, Shigeto Kabuki, Etsuo Kunieda, et al. Heavy Ion Irradiation Reduces Vulnerability to Atrial Tachyarrhythmias - Gap Junction and Sympathetic Neural Remodeling. Circulation journal : official journal of the Japanese Circulation Society. 2022
Keigo Arai, Akihiro Kuwahata, Daisuke Nishitani, Ikuya Fujisaki, Ryoma Matsuki, Yuki Nishio, Zonghao Xin, Xinyu Cao, Yuji Hatano, Shinobu Onoda, et al. Millimetre-scale magnetocardiography of living rats with thoracotomy. Communications Physics. 2022. 5. 1
Masatoshi Yamazaki, Naoki Tomii, Koichi Tsuneyama, Hiroki Takanari, Ryoko Niwa, Haruo Honjo, Itsuo Kodama, Tatsuhiko Arafune, Naomasa Makita, Ichiro Sakuma, et al. Rotors anchored by refractory islands drive torsades de pointes in an experimental model of electrical storm. Heart rhythm. 2022. 19. 2. 318-329
Shibata N, Inada S, Nakazawa K, Ashihara T, Tomii N, Yamazaki M, Honjo H, Seno H, Sakuma I. Mechanism of ventricular fibrillation: Current status and problems. Adv Biomed Eng. 2022. 11. 117-135

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MISC (37)：

岩宮賢, 井原健介, 富井直輝, 山崎正俊, 黒柳秀人, 佐久間一郎, 古川哲史, 笹野哲郎. 心房細動モデルマウスのoptical mappingによる評価. 心電学関連春季大会プログラム・抄録集(Web). 2021. 2021
Sakuma I, Kobayashi T, Seno H, Akagi Y, Nakagawa K, Yamazaki M, Tomii N. Application of structured light Illumination and compressed sensing to high speed laminar optical fluorescence tomography. IFMBE Proceedings 2019. 2019. 75. 1216-19
Sakuma I, Yamazaki M, Tomii N. Bioengineering Approaches in Arrhythmia Research at the University of Tokyo: https://www.youtube.com/watch?v=9yXxdRpzwJc. Heart Rhythm TV 2018, USA. 2018
Tomii N, Yamazaki M, Shibata N, Honjo H, Sakuma I. Statistical Guideline of Threshold Determination for Cardiac Spiral Wave Center Detection Using Phase Variance. IFMBE Proceedings 2018. 2018. 68. 299-302
Y. Kushiyama, H. Honjo, R. Niwa, H. Takanari, M. Yamazaki, Y. Takemoto, I. Sakuma, I. Kodama, K. Kamiya. Partial blockade of IK1 destabilizes the rotation center of spiral wave reentry without enhancement of wavefront-tail interactions in the arm. EUROPEAN HEART JOURNAL. 2012. 33. 820-820

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Patents (4)：

解析マップ作成装置およびプログラム
心筋局所冷却とリアルタイム・フィードバックを組み合わせた心室細動の予防装置
Ventricular Fibrillation Preventing Apparatus and Defibrillating Apparatus
心筋局所冷却と直流通電を用いた植込み型除細動器

Books (9)：

「不整脈研究のための心臓膜電位光学マッピング」第3編医用工学の応用事例・第2章循環器系・2不整脈治療I
(株)エヌ・ティー・エス 2022
位相分散解析の不整脈治療計画研究への展開
BIO Clinica 2020;35(9):__ 2020
Arrhythmia 2017
2017
In Cardiac Electrophysiology: From Cell to Bedside 6th Edition edited by Zipes DP and Jalife J
ELSEVIER SAUNDERS 2014
Is driver ablation for persistent atrial fibrillation effective or not?
Nikkei Business Publications, Inc. 2014

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Education (2)：

2002 - 2006 Nagoya University Graduate School of Medicine
1991 - 1997 Kawasaki Medical School

Professional career (1)：

MD, PhD (Nagoya University)

Work history (14)：

2022/06 - 現在 Nagano Hospital President, Director of Cardiology
2019/04 - 現在 The University of Tokyo Medical Device Development and Regulation Research Center Associate Professor
2021/02 - 2022/05 Nagano Hospital Vice-president, director of cardiology
2017/02 - 2020/03 Rhode Island Hospital and Brown University Cardiovascular Research Center Visiting Assistant Professor
2017/04 - 2019/03 The University of Tokyo Medical Device Development and Regulation Research Center Chief Scientist, Assistant Professor

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Committee career (4)：

2018 - 現在日本不整脈心電学会医工連携部会委員
2017 - 現在日本不整脈心電学会学術大会プログラム委員
2016 - 現在 The Japanese Heart Rhythm Society Councilor
2016 - 現在日本不整脈心電学会評議員

Awards (7)：

2019/09 - BRAVE2019 準優秀賞、ライフサイエンス賞(LINK-J特別賞)
2018 - 生体医工学シンポジウム2018 ポスターアワード Compressed Laminar Optical Tomography(CLOT)計測を可能とする光学計測システムの開発
2018 - 生体医工学シンポジウム2019 ベストリサーチアワード三次元計測とプロジェクションマッピング仮想電極分極現象を用いた Spir4l Reentry 旋回中心制御
2011/09 - Asia Pacific Heart Rhythm Society Young Investigator Award (1st prize) Role of the Left Atrial Anatomy in the Maintenance of Three-Dimensional Scroll Waves in Acute, Stretch-Related and Cholinergic Atrial Fibrillation
2010/05 - Heart Rhythm Society, USA Heart Rhythm Journal Award 2010 Mechanisms of stretch-induced atrial fibrillation in the presence and the absence of adrenocholinergic stimulation: interplay between rotors and focal discharges.

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Association Membership(s) (6)：

American Heart Association , Heart Rhythm Society , JAPANESE HEART RHYTHM SOCIETY , 日本心電学会 , JAPANESE CIRCULATION SOCIETY , THE JANPANESE SOCIETY OF INTERNAL MEDICINE

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