Rchr
J-GLOBAL ID:201101015581485763   Update date: Feb. 01, 2024

sasaki junko

sasaki junko
Affiliation and department:
Homepage URL  (1): http://www.tmd.ac.jp/pip/index.html
Research field  (4): Functional biochemistry ,  Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Medical biochemistry
Research keywords  (5): シグナル伝達 ,  リン脂質 ,  ノックアウトマウス ,  遺伝子改変マウス ,  イノシトールリン脂質
Research theme for competitive and other funds  (26):
  • 2023 - 2026 新規リン脂質によるがん悪性化制御機構の解明
  • 2021 - 2024 大脳基底核異常による不随意運動モデルの作成と遺伝子治療開発
  • 2021 - 2024 がんの発生・悪性化における微量リン脂質分子種の重要性
  • 2020 - 2022 イノシトールリン脂質によるステロイドホルモン産生酵素の制御と性スペクトラム
  • 2018 - 2019 リン脂質代謝が規定する性スペクトラム
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Papers (61):
  • Tamara A M Chessa, Piotr Jung, Arqum Anwar, Sabine Suire, Karen E Anderson, David Barneda, Anna Kielkowska, Barzan A Sadiq, Ieng Wai Lai, Sergio Felisbino, et al. PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate. Mol Cell. 2023. 83. 16. 2991-3009.e13
  • Dang Minh Tran, Nozomu Yoshioka, Norihisa Bizen, Yukiko Mori-Ochiai, Masato Yano, Shogo Yanai, Junya Hasegawa, Satoshi Miyashita, Mikio Hoshino, Junko Sasaki, et al. Attenuated cerebellar phenotypes in Inpp4a truncation mutants with preserved phosphatase activity. Disease models & mechanisms. 2023. 16. 7
  • Tsukasa Oikawa, Junya Hasegawa, Naomi Ohnishi, Yasuhito Onodera, Ari Hashimoto, Junko Sasaki, Takehiko Sasaki, Koji Ueda, Hisataka Sabe. p53 controls the nuclear entry and epigenetic modification of H3.1 by downregulating nuclear phosphatidic acid. 2023
  • Akihiro Iguchi, Sho Takatori, Shingo Kimura, Hiroki Muneto, Kai Wang, Hayato Etani, Genta Ito, Haruaki Sato, Yukiko Hori, Junko Sasaki, et al. INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model. iScience. 2023. 26. 4. 106375-106375
  • Takahito Miyake, Yuichi Inoue, Xinyan Shao, Takehito Seta, Yuto Aoki, Khanh Tien Nguyen Pham, Yuichi Shichino, Junko Sasaki, Takehiko Sasaki, Masahito Ikawa, et al. Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm. Cell reports. 2023. 42. 3. 112157-112157
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MISC (94):
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Books (3):
  • Chronic Inflammation: Mechanisms and Regulation
    Springer 2016
  • 再生医療のための分子生物
    幹細胞のシグナル伝達~PI3K・Akt~ 2006
  • マウスラボマニュアル
    シュプリンガー・フェアラーク社 2003
Professional career (1):
  • 博士(薬学) (東京大学)
Work history (5):
  • 2018 - 現在 Tokyo Medical and Dental University
  • 2014 - 2018 Akita University Graduate School of Medicine
  • 2008 - 2014 Akita University Graduate School of Medicine
  • 2003 - 2008 Akita University Graduate School of Medicine
  • 2000 - 2003 (財)東京都医学研究機構・(財)東京都臨床医学総合研究所・財団法人 研究員
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