Fukuya Masahiro

フカヤマサヒロ | Fukuya Masahiro

Affiliation and department：

Research field (3)： Anatomy , Neuroscience - general , Neuroanatomy and physiology

Research keywords (23)：シナプス可塑性 , BRAG2 , 脳 , 平行繊維 , シナプス , プルキンエ細胞 , 登上繊維 , 発達 , 神経科学 , AMPA型グルタミン酸受容体 , 抑制性ニューロン , アストロサイト , NMDA受容体 , TARPs , 免疫電子顕微鏡法 , ノックアウトマウス , 細胞内局在 , stargazinファミリー , 海馬 , 大脳皮質 , バーグマングリア , グルタミン酸受容体 , 小脳

Research theme for competitive and other funds (6)：

2022 - 2025 Regulatory mechanisms for perisynaptic accumulation of mGluRs and synaptic plasticity via cytohesin-2 signaling pathway
2015 - 2018 Elucidating synaptic mechanisms and treatment of epileptic encephalopathy associated with CDKL5 mutations
2012 - 2015 Characterization of BDNF expression and anxiety-related behavior in pilocarpine model mice.
2007 - 2011 Molecular mechanisms for calcium-mediated refinement of competitive synaptic wiring in the brain
2003 - 2004 Calcium Signaling and Cerebellar Synaptic Circuit Development

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Papers (128)：

Moeko Nakashima, Tomoko Shiroshima, Masahiro Fukaya, Takeyuki Sugawara, Hiroyuki Sakagami, Kazuki Yamazawa. C-terminal truncations in IQSEC2: implications for synaptic localization, guanine nucleotide exchange factor activity, and neurological manifestations. Journal of human genetics. 2024
Yoshinobu Hara, Takehiko Katsuyama, Masahiro Fukaya, Takeyuki Sugawara, Tomoko Shiroshima, Tetsushi Sadakata, Noriko Osumi, Hiroyuki Sakagami. ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development. eneuro. 2023. 10. 11. ENEURO.0125-23.2023
Akiko Ito, Masahiro Fukaya, Takeyuki Sugawara, Yoshinobu Hara, Hirotsugu Okamoto, Junji Yamauchi, Hiroyuki Sakagami. Cytohesin-2 mediates group I metabotropic glutamate receptor-dependent mechanical allodynia through the activation of ADP ribosylation factor 6 in the spinal cord. Neurobiology of Disease. 2021. 159. 105466-105466
Kanta Ibuchi, Masahiro Fukaya, Tetsuro Shinohara, Yoshinobu Hara, Tomoko Shiroshima, Takeyuki Sugawara, Hiroyuki Sakagami. The Vps52 subunit of the GARP and EARP complexes is a novel Arf6-interacting protein that negatively regulates neurite outgrowth of hippocampal neurons. Brain research. 2020. 1745. 146905-146905
Masahiro Fukaya, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Masahiko Watanabe, Hiroyuki Sakagami. BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at Excitatory Postsynapses through the Interaction with PSD-95 and Endophilin 3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2020. 40. 22. 4277-4296

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MISC (29)：

Kosuke Okuda, Aya Watanabe, Shizuka Kobayashi, Toshiya Manabe, Keizo Takao, Tsuyoshi Miyakawa, Masahiro Fukaya, Hiroyuki Sakagami, Masashi Mizuguchi, Teruyuki Tanaka. The roles of CDKL5, a causative gene for neurodevelopmental disorders with infantile spasms, in synaptic transmission, emotion and learning/memory. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 64P-64P
Shizuka Kobayashi, Yamato Hida, Hiroyoshi Ishizaki, Eiji Inoue, Miki Tanaka-Okamoto, Miwako Yamasaki, Taisuke Miyazaki, Masahiro Fukaya, Isao Kitajima, Yoshimi Takai, et al. The active zone protein CAST regulates synaptic vesicle recycling and quantal size. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S67-S67
Yoshinobu Hara, Nobuhiko Nishimura, Masahiro Fukaya, Hiroyuki Sakagami. Expression and functional roles of phosphatidylinositol 4-phosphate 5-kinase (PIP5K) gamma in the developing cerebral cortex. NEUROSCIENCE RESEARCH. 2011. 71. E128-E128
Masahiro Fukaya, Yoshinobu Hara, Hiroyuki Sakagami. Postsynaptic and endosomal localization of BRAG2/GEP100 in the adult mouse brain. NEUROSCIENCE RESEARCH. 2011. 71. E321-E321
藤川恵子, 岩田岳, 門谷華子, 赤堀正和, 深谷昌弘, 渡辺雅彦, BARNETT Edward, SWAT Wojciech, 井上馨. 自然発症高眼圧ヒト緑内障表現型を示すVav2/Vav3遺伝子欠損マウスとヒトでの一塩基多型解析の検討. 日本緑内障学会抄録集. 2010. 21st

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Professional career (1)：

博士(医学) (北海道大学)

Work history (5)：

2019/10 - 現在 Kitasato University School of Medicine
2010/05 - 2019/09 Kitasato University School of Medicine
2008 - 2010/04 北海道大学医学(系)研究科(研究院) 助教
2008/04 - 2009/09 ジョンズ・ホプキンス大学医学部神経科学部門客員研究員
2003/04 - 2008/03 北海道大学大学院医学研究科助手

Awards (2)：

2008/03 - 日本解剖学会平成19年度日本解剖学会奨励賞 AMPA型およびNMDA型グルタミン酸受容体の細胞内局在制御機構に関する分子解剖学的研究
2004/03 - 北海道大学医学研究科第23回高桑栄松奨学基金奨励賞 NMDA 型グルタミン酸受容体のシナプス局在制御機構に関する分子解剖学的研究

Association Membership(s) (3)：

Society for Neuroscience , 日本解剖学会 , 日本神経科学学会

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