Hanamura Kenji

ハナムラケンジ | Hanamura Kenji

Affiliation and department：
Job title： Professor
Homepage URL (2)： https://www.nuhw.ac.jp/n/teacher/rt/%E8%8A%B1%E6%9D%91-%E5%81%A5%E6%AC%A1/ , https://en.nuhw.ac.jp/undergraduate/rt.html

Research field (8)： Neuroscience - general , Pharmacology , Cell biology , Physiology , Neuroanatomy and physiology , Anatomy , Radiology , Environmental effects of radiation

Research keywords (9)： Radiation Biology , 神経発達 , synapse formation , 発達障害 , リン酸化 , アクチン , 海馬初代培養神経細胞 , 免疫蛍光染色 , 放射線感受性

Research theme for competitive and other funds (14)：

2020 - 2023 FN3を持つ神経発達障害関連分子の細胞外チロシンリン酸化とその役割の解析
2017 - 2020 アクチン動態に基づく新たなシナプス可塑性モデル
2020 - 新規生体機能チップを用いた神経細胞に対する放射線のバイスタンダー効果の解析
2018 - 2019 加齢依存的な認知機能低下の制御機構の解明
2017 - 2018 認知機能低下に伴う神経シナプス形態変化の脳内イメージング解析

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Papers (41)：

Mai Yamamura, Kenji Hanamura, Noriko Koganezawa, Senami Furubayashi, Tomoaki Shirao, Hiroshi Kawabe. Impacts of methotrexate on survival, dendrite development, and synapse formation of cortical neurons. Genes to cells : devoted to molecular & cellular mechanisms. 2023. 28. 8. 563-572
Saki Katsube, Noriko Koganezawa, Kenji Hanamura, Katherine J. Cuthill, Victor Tarabykin, Mateusz C. Ambrozkiewicz, Hiroshi Kawabe. The murine ortholog of Kaufman oculocerebrofacial syndrome gene Ube3b is crucial for the maintenance of the excitatory synapses in the young adult stage. Neuroscience Letters. 2023. 797. 137059-137059
Min-Jue Xie, Hideshi Yagi, Tokuichi Iguchi, Hiroyuki Yamazaki, Kenji Hanamura, Hideo Matsuzaki, Tomoaki Shirao, Makoto Sato. Phldb2 is essential for regulating hippocampal dendritic spine morphology through drebrin in an adult-type isoform-specific manner. Neuroscience Research. 2022. 185. 1-10
Anggraeini Puspitasari, Fabio Squarcio, Martina Quartieri, Cristina Totis, Timna Hitrec, Akihisa Takahashi, Yukari Yoshida, Kenji Hanamura, Tomoko Yako, Matteo Cerri, et al. Synthetic torpor protects rats from exposure to accelerated heavy ions. Scientific Reports. 2022. 12. 1
Noriko Koganezawa, Kenji Hanamura, Manuela Schwark, Dilja Krueger-Burg, Hiroshi Kawabe. Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO mice. Biochemical and biophysical research communications. 2021. 582. 144-149

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MISC (30)：

YAMAZAKI Hiroyuki, HANAMURA Kenji, SEGAWA Banri, TSUKAHARA Narutoshi, MURAKAMI Akikazu, SHIRAO Tomoaki. Live cell imaging of endogenous drebrin using camelidae single-domain antibody. Journal of Physiological Sciences (Web). 2020. 70. Supplement 1
YAMAZAKI Hiroyuki, HANAMURA Kenji, TSUKAHARA Narutoshi, SEGAWA Banri, MURAKAMI Akikazu, SHIRAO Tomoaki. ドレブリンナノボディの開発. 日本神経化学会大会抄録集(Web). 2019. 62nd
YAMAZAKI Daiju, GOTO Kazue, KOGANEZAWA Noriko, HANAMURA Kenji, SHIRAO Tomoaki, SEKINO Yuko, KANDA Yasunari. Development of testing method for neural activity network using hippocampal neuron. Annual Meeting of the Japanese Society of Toxicology. 2017. 44. 0. P-202
Tomoaki Shirao, Yuta Ishizauka, Kenji Hanamura, Noriko Koganezawa, Mao Ootsu, Hiroyuki Yamazaki. Differential effects of astemizole on the neurite growth and synaptogenesis of neurons. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2016. 81. 387-387
Nobuhiko Kojima, Hiroki Yasuda, Kenji Hanamura, Tomoaki Shirao. Isoform conversion of drebrin is required for hippocampus-dependent learning and synaptic plasticity in the elderly. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 183P-183P

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Books (3)：

iPS細胞の安全・高品質な作製技術
技術情報協会 2016 ISBN:9784861046292
オックスフォード生理学原書4版
丸善出版 2016 ISBN:9784621300084
Development and Plasticity in Sensory Thalamus and Cortex
Springer US 2006 ISBN:9780387386072

Lectures and oral presentations (5)：

High-throughput imaging analysis using cultured neurons for detecting phencyclidine-like substances
(The 9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019) 2019)
The role of an actin-binding protein drebrin and its isoform-specific dynamics in dendritic spines
(2018)
High content imaging analysis of drebrin clusters along dendrites regulated by NMDA receptor activity
(2018)
Maturation of actin cytoskeleton in dendritic spines and the age-dependent role in synaptic plasticity
(2016)
Extracellular EphB tyrosine phosphorylation regulates EphB-NMDAR interaction and function
(Neuroscience 2013 (Annual Meeting of Society for Neuroscience) 2013)

Education (3)：

1998 - 2002 Osaka University Graduate School of Engineering Science Department of Biophysical Engineering
1996 - 1998 Osaka University Graduate School of Engineering Science Department of Biophysical Engineering
1992 - 1996 Osaka University School of Engineering Science Department of Biophysical Engineering

Professional career (1)：

PhD (Osaka University)

Work history (10)：

2023/05 - 現在 Gunma University Department of Pharmacology , Graduate School of Medicine Visiting Professor
2023/05 - 現在 Niigata University of Health and Welfare Department of Radiological Technology, Faculty of Medical Technology Professor
2020/04 - 2023/04 Gunma University Department of Pharmacology, Gunma University Graduate School of Medicine Associate Professor
2018/08 - 2020/03 Gunma University Department of Neurobiology and Behavior, Graduate School of Medicine Associate Professor
2015/04 - 2018/07 Gunma University Department of Neurobiology and Behavior, Graduate School of Medicine Assistant Professor

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Committee career (4)：

2019/09 - 現在北関東医学会評議員
2018/03 - 現在日本生理学会評議員
2015/04 - 2015/09 第58回日本神経化学大会(さいたま)(大会長:白尾智明) 組織委員
2005/03 - 2006/03 第83回日本生理学会(前橋)(大会長:小澤瀞司) プログラム委員・実行委員

Association Membership(s) (4)：

KITAKANTO Medical Society , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE PHYSIOLOGICAL SOCIETY OF JAPAN , THE JAPAN NEUROSCIENCE SOCIETY

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