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J-GLOBAL ID:201101092948336012   Update date: Apr. 09, 2024

Okamoto Hitoshi

オカモト ヒトシ | Okamoto Hitoshi
Affiliation and department:
Job title: Visiting Senior Scientist
Homepage URL  (2): https://cbs.riken.jp/jp/faculty/h.okamoto/index.htmlhttps://cbs.riken.jp/en/faculty/h.okamoto/index.html
Research field  (2): Developmental biology ,  Neuroscience - general
Research keywords  (32): 包括脳ネットワーク ,  統合脳・神経回路機能 ,  カルシウムイメージング ,  HNK-1 ,  迷走運動神経 ,  Isl-1遺伝子 ,  Apterous ,  ノッチシグナル ,  ディファレンシャルディスプレイ ,  zebrafish ,  手綱核 ,  細胞移動 ,  中脳分化 ,  ホメオドメイン蛋白 ,  homeodomain ,  Isl-1 ,  視蓋 ,  小脳分化 ,  ディファレンシャルディスプレー ,  神経細胞分化 ,  サブトラクション ,  中脳後脳境界 ,  LH2 ,  運動神経細胞 ,  小脳 ,  トランスジェニック ,  中脳 ,  中脳・後脳境界部 ,  運命決定 ,  Islet-3 ,  LIM ,  ゼブラフィッシュ
Research theme for competitive and other funds  (37):
  • 2021 - 2025 Study of the switching regulation of social and cognitive behaviors by the habenula-interpeduncular nucleus pathway
  • 2016 - 2021 Neural circuit mechanisms for regulation of social conflicts
  • 2016 - 2019 社会的闘争を制御する神経回路機構
  • 2011 - 2016 Elucidation of the Neral Computation for Prediction and Decision Making
  • 2011 - 2016 Imaging and manipulation of the neural circuits for decision making
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Papers (124):
  • Yuki Tanimoto, Hisaya Kakinuma, Ryo Aoki, Toshiyuki Shiraki, Shin-Ichi Higashijima, Hitoshi Okamoto. Transgenic tools targeting the basal ganglia reveal both evolutionary conservation and specialization of neural circuits in zebrafish. Cell reports. 2024. 113916-113916
  • Kotaro Shibayama, Haruna Nakajo, Yuki Tanimoto, Hisaya Kakinuma, Toshiyuki Shiraki, Takashi Tsuboi, Hitoshi Okamoto. The serotonergic neurons derived from rhombomere 2 are localized in the median raphe and project to the dorsal pallium in zebrafish. Neuroscience research. 2024
  • Yoshiro Yonezawa, Long Guo, Hisaya Kakinuma, Nao Otomo, Soichiro Yoshino, Kazuki Takeda, Masahiro Nakajima, Toshiyuki Shiraki, Yoji Ogura, Yohei Takahashi, et al. Identification of a functional susceptibility variant for adolescent idiopathic scoliosis that upregulates EGR1-mediated UNCX expression. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2022. 38. 1. 144-153
  • Makio Torigoe, Tanvir Islam, Hisaya Kakinuma, Chi Chung Alan Fung, Takuya Isomura, Hideaki Shimazaki, Tazu Aoki, Tomoki Fukai, Hitoshi Okamoto. Zebrafish capable of generating future state prediction error show improved active avoidance behavior in virtual reality. Nature Communications. 2021. 12. 1
  • Gerissa Fowler, Danielle French, April Rose, Paige Squires, Catarina Anecito da Silva, Shinya Ohata, Hitoshi Okamoto, Curtis R French. Protein fucosylation is required for Notch dependent vascular integrity in zebrafish. Developmental biology. 2021
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MISC (98):
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Books (4):
  • 現代生物科学入門,第4巻
    岩波書店 2009
  • シリーズ脳科学、脳の発生と発達(岡本仁編)
    東京大学出版会 2008
  • 脳科学の最前線(上巻、脳と認知と進化)、理化学研究所、脳科学総合研究センター編
    講談社ブルーバックス 2007
  • 脳科学の進歩、〜分子から心まで〜
    大学教育振興会 2006
Professional career (2):
  • MD (The University of Tokyo)
  • 理学博士 (東京大学)
Work history (27):
  • 2024/04 - 現在 RIKEN Center for Brain Science Visiting Senior Scientist
  • 2018/04 - 2024/03 RIKEN Center for Brain Science
  • 2009/04 - 2018/03 RIKEN Brain Science Institute Laboratory for Developmental Gene Regulation senior team leader
  • 2008/04 - 2018/03 RIKEN Brain Science Institute Deputy Director
  • 2005 - 2009 RIKEN
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Awards (1):
  • 1914/07 - Japanese Society for Neuroscience Tokizane Prize
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