Rchr
J-GLOBAL ID：201201069007773181   Update date: Apr. 14, 2024

Shimomura Kenju

Shimomura Kenju
Affiliation and department：
Fukushima Medical University

About Fukushima Medical University


Research field  (1)： Internal medicine - General
Research keywords  (6)： 包括脳ネットワーク ,  sulfonylurea ,  DEND syndrome ,  neonatal diabetes ,  K(ATP) channel ,  Diabetes
Research theme for competitive and other funds  (7)：
  • 2020 - 2023 PIP2によるKATPチャネル・インスリン分泌制御ならびに糖尿病治療への応用
  • 2018 - 2021 The study of anti-obesity effect by recovery of endogenous oxytocin secretion and its clinical implication
  • 2017 - 2020 Involvement of brain KATP channel with pathology of sarcopenia and fraility
  • 2015 - 2018 The study of development of oxytocinergic neutral circuit responding to energy status in childhood
  • 2014 - 2017 Contribution of KATP channel in PVN oxytocin neurons for food intake regulation.
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Papers (111)：
  • Shigeki Kitamura, Naoya Murao, Shoko Yokota, Masaru Shimizu, Tomoyuki Ono, Yusuke Seino, Atsushi Suzuki, Yuko Maejima, Kenju Shimomura. Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion. BMC research notes. 2023. 16. 1. 202-202
  • Yuko Ono, Masafumi Saito, Kazuho Sakamoto, Yuko Maejima, Shingen Misaka, Kenju Shimomura, Nobuto Nakanishi, Shigeaki Inoue, Joji Kotani. C188-9, a specific inhibitor of STAT3 signaling, prevents thermal burn-induced skeletal muscle wasting in mice. Frontiers in Pharmacology. 2022. 13
  • Yuko Maejima, Shoko Yokota, Tomoyuki Ono, Zhiqian Yu, Megumi Yamachi, Shizu Hidema, Kenneth E Nollet, Katsuhiko Nishimori, Hiroaki Tomita, Hiroyuki Yaginuma, et al. Identification of oxytocin expression in human and murine microglia. Progress in neuro-psychopharmacology & biological psychiatry. 2022. 119. 110600-110600
  • Shingen Misaka, Yuko Ono, R. Verena Taudte, Eva Hoier, Hiroshi Ogata, Tomoyuki Ono, Jörg König, Hiroshi Watanabe, Martin F. Fromm, Kenju Shimomura. Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers. Clinical Pharmacology & Therapeutics. 2022
  • Yuko Maejima, Shoichiro Horita, Shoko Yokota, Megumi Yamachi, Masaru Shimizu, Tomoyuki Ono, Zhiquian Yu, Hiroaki Tomita, Kenju Shimomura. Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia. Molecular and cellular neurosciences. 2022. 120. 103734-103734
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MISC (15)：
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Lectures and oral presentations  (2)：
  • KATP channel and neonatal diabetes
    (Annual Meetings of Japan Diabetes Society 2010)
  • Properties of KATP channel on insulin secretion. Studies of mutations in neonatal diabetes
    (Annual Meetings of Physiological Society in Japan 2010)
Education (2)：
  • 1999 - 2004 Gunma University Faculty of Medicine
  • 1991 - 1997 Fukushima Medical University
Professional career (1)：
  • 医学博士 (群馬大学)
Work history (7)：
  • 2017/04 - 現在 Fukushima Medical University Department of Bioregulation and Pharmacological Medicine Professor
  • 2015/12 - 現在 Fukushima Medical University Department of Medical Elactrophysiology Professor
  • 2014/08 - 2017/03 Fukushima Medical University Department of Electrophysiology and Oncology Prof
  • 2012/04 - 2014/07 Division of Integrative Physiology, Jichi Medical University
  • 2004/05 - 2012/04 Department of Physiology, Oxford University
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Awards (2)：
  • 2010 - オックスフォード大学 メリット賞
  • 2005 - オックスフォード大学 メリット賞
Association Membership(s) (2)：
THE JANPANESE SOCIETY OF INTERNAL MEDICINE ,  JAPAN DIABETES SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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