Yoshikawa Harunori

ヨシカワハルノリ | Yoshikawa Harunori

Affiliation and department：
Homepage URL (1)： https://www.iams.tokushima-u.ac.jp/

Research field (3)： Molecular biology , Chemical biology , Applied molecular and cellular biology

Research keywords (6)： RNA , SEC HPLC , ribosome , proteomics , nucleolus , ribosome biogenesis

Research theme for competitive and other funds (8)：

2022 - 2026 定量プロテオミクスが紐解く新規タンパク質複合体によるHPV陽性癌の新たな病因論
2021 - 2024 ポストリソソーム生物学研究領域の創成支援
2021 - 2024 体液のマルチオミクス解析による寿命を制御するポストリソソーム経路の解明
2021 - 2024 Functional characterization of Myc-depedent ribosomes by Ribo Mega-SEC coupled to mass spectrometry-based proteomics
2021 - 2021 がん組織特異的な特殊化リボソーム解析法の確立とその分子的実体の解明

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Papers (34)：

Alejandro J. Brenes, Eva Griesser, Linda V. Sinclair, Lindsay Davidson, Alan R. Prescott, Francois Singh, Elizabeth K.J. Hogg, Carmen Espejo-Serrano, Hao Jiang, Harunori Yoshikawa, et al. Proteomic and functional comparison between human induced and embryonic stem cells. eLife. 2024
Daishiro Kobayashi, Masaya Deda, Junya Hayashi, Kota Hidaka, Yutaka Kohmura, Takaaki Tsunematsu, Kohei Nishino, Harunori Yoshikawa, Kento Ohkawachi, Kiyomi Nigorikawa, et al. Sulfoxide-mediated Cys-Trp-selective bioconjugation that enables protein labeling and peptide heterodimerization. 2024
Joana R. C. Faria, Michele Tinti, Catarina A. Marques, Martin Zoltner, Harunori Yoshikawa, Mark C. Field, David Horn. An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome. Nature Communications. 2023
Kohei Nishino, Harunori Yoshikawa, Kou Motani, Hidetaka Kosako. Optimized Workflow for Enrichment and Identification of Biotinylated Peptides Using Tamavidin 2-REV for BioID and Cell Surface Proteomics. Journal of Proteome Research. 2022
Takumi Maruhashi, Daisuke Sugiura, Il-Mi Okazaki, Kenji Shimizu, Takeo K Maeda, Jun Ikubo, Harunori Yoshikawa, Katsumi Maenaka, Naozumi Ishimaru, Hidetaka Kosako, et al. Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity. Immunity. 2022. 55. 5. 912-924

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MISC (5)：

吉川治孝. co-fractionation MS 新たな網羅的タンパク質複合体解析法. 実験医学別冊決定版質量分析活用スタンダード. 2023. 293-299
吉川治孝, Angus I. Lamond. Ribo Mega-SEC:サイズ排除クロマトグラフィーによる簡便なリボソームの分離法. 日本プロテオーム学会誌. 2020. 5. 1. 13-22
Takahashi Nobuhiro, Yoshikawa Harunori, Izumikawa Keiichi, Ishikawa Hideaki. Proteomic Technologies Reveal Regulatory Mechanism Underlining Ribosome Biogenesis in Human Cells. Proteome Letters. 2017. 2. 1. 7-15
吉川治孝, 泉川桂一, 石川英明, 高橋信弘. リボソームの機能調節と疾患 II.リボソームRNAの転写後修飾とアセンブリー II-1 リボソームサブユニット生合成の調節. 生化学. 2013. 85. 10. 861-870
H. Yoshikawa, W. Komatsu, T. Hayano, Y. Miura, K. Homma, K. Izumikawa, H. Ishikawa, N. Miyazawa, H. Tachikawa, Y. Yamauchi, et al. Involvement of p32, fibrillarin, and Nop52 in pre-90S particle separation during human ribosome biogenesis. MOLECULAR BIOLOGY OF THE CELL. 2011. 22

Lectures and oral presentations (27)：

定量プロテオミクスによる核小体リボソーム生合成過程の解明
(日本プロテオーム学会2023年大会 JPrOS2023 (21st JHUPO) 2023)
Co-Fractionation MS(CF-MS)による細胞内巨大タンパク質複合体の解析
(第23回日本蛋白質科学会年会 2023)
Co-Fractionation MSによる細胞内巨大タンパク質複合体の解析
(第71回質量分析総合討論会 2023)
細胞内タンパク質合成装置リボソームの効率的な解析法 Ribo Mega-SECの確立とその応用
(徳島大学大学院医歯薬学研究部 2022年度骨・筋とCaクラスター・ミニリトリート 2023)
核小体ヒトプレリボソームの新規分離法が切り拓くリボソーム合成因子の網羅的解析
(第45回日本分子生物学会年会 2022)

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Education (1)：

- 2011 Tokyo University of Agriculture and Technology United Graduate School of Agricultural Science

Professional career (1)：

Work history (4)：

2020/10 - 現在 The University of Tokushima Institute of Advanced Medical Sciences
2014/10 - 2020/08 University of Dundee Centre for Gene Regulation & Expression Postdoctoral Reseach Assistant
2011/10 - 2014/09 Tokyo University of Agriculture and Technology Graduate School of Agriculture
2013/04 - 2013/09 Tokyo University of Agriculture and Technology

Awards (7)：

2019/07 - JPrOS 2019 (17th JHUPO) and JES 2019 Joint Annual Meeting Poster award Towards the comprehensive characterisation of cellular protein complexes by Size Exclusion Chromatography
2019/03 - Poster Prize: Proteomics in Cell Biology and Disease Mechanisms, EMBL-WELLCOME GENOME CAMPUS CONFERENCE (Heidelberg, Germany)
2015/02 - European Commission Marie Skłodowska-Curie Individual Fellowships MSCA-IF-2014-EF
2014/12 - Uehara Memorial Foundation Postdoctoral Fellowship
2014/02 - Naito Foundation Postdoctoral Fellowship of Research Abroad

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Association Membership(s) (2)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本プロテオーム学会

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