Rchr
J-GLOBAL ID：201201079707068530   Update date: Feb. 28, 2024

Sawabe Motoji

サワベ モトジ | Sawabe Motoji
Affiliation and department：
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Biomedical Sciences and Engineering Division of Biomedical Laboratory Sciences Department of Molecular Pathology

About Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Biomedical Sciences and Engineering Division of Biomedical Laboratory Sciences Department of Molecular Pathology


Job title： Professor
Homepage URL  (1)： http://kaken.nii.ac.jp/d/r/30196331.ja.html
Research field  (3)： Human pathology ,  Anatomy ,  Genetics
Research keywords  (30)： ゲノム ,  老化 ,  病理学 ,  免疫学 ,  循環器・高血圧 ,  アルツハイマー病 ,  神経科学 ,  痴呆 ,  脳神経疾患 ,  病理 ,  遺伝子多型 ,  脳・神経 ,  動脈硬化 ,  パーキンソン病 ,  メタボリック症候群 ,  心筋リモデリング ,  ホモシスチン ,  サイトカイン ,  免疫・炎症 ,  郵脈硬化 ,  TCAP ,  遺伝子 ,  肥満 ,  レアバリアント ,  拡張型心筋症 ,  Z帯 ,  老年病 ,  動脈硬化症 ,  肺癌 ,  炎症
Research theme for competitive and other funds  (25)：
  • 2017 - 2019 Lipoprotein(a)と悪性腫瘍との関連についての分子疫学的・病理学的研究
  • 2014 - 2018 Prevention of metabolic syndrome and atherosclerosis by personal genome information
  • 2014 - 2016 動脈老化と大動脈解離症におけるタンパク質発現・翻訳後修飾解析と病理組織学的解析
  • 2012 - 2015 Explaining the mechanism of bone weakness in patients with chronic obstructive pulmonary disease: A perspective based on analysis of the whole body collagen.
  • 2010 - 2012 Molecular epidemiology of metabolic syndrome and atherosclerosis initiating from genome wide association study
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Papers (372)：
  • Mayumi Kinoshita, Motoji Sawabe, Yurie Soejima, Makiko Naka Mieno, Tomio Arai, Naoko Honma. Gross Cystic Disease Fluid Protein-15 (GCDFP-15) Expression Characterizes Breast Mucinous Carcinomas in Older Women. Diagnostics (Basel, Switzerland). 2022. 12. 12
  • Morita Y, Kurano M, Sakai E, Sawabe M, Aoki J, Yatomi Y. Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy. Journal of lipid research. 2021. 100120-100120
  • Sato Mizuho, Tsumoto Hiroki, Toba Ayumi, Soejima Yurie, Arai Tomio, Harada Kazumasa, Miura Yuri, Sawabe Motoji. Proteome analysis demonstrates involvement of endoplasmic reticulum stress response in human myocardium with subclinical left ventricular diastolic dysfunction(和訳中). Geriatrics & Gerontology International. 2021. 21. 7. 577-583
  • Yurie Soejima, Miho Takeuchi, Nao Miyamoto, Motoji Sawabe, Toshio Fukusato. ITGB6-Knockout Suppresses Cholangiocarcinoma Cell Migration and Invasion with Declining PODXL2 Expression. International Journal of Molecular Sciences. 2021. 22. 12. 6303-6303
  • 副島 友莉恵, 竹内 美穂, 宮本 菜央, 沢辺 元司, 福里 利夫. ITGB6ノックアウト胆管癌細胞株の機能解析と遺伝子発現変化. 日本病理学会会誌. 2021. 110. 1. 317-317
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MISC (97)：
  • Maidina Abudushataer, Noriko Sato, Makiko Mieno, Motoji Sawabe, Masaaki Muramatsu, Tomio Arai. Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study. BMC cancer. 2020. 20. 1. 186-186
  • M. Kinoshita, Y. Hamashima, S. Esaka, M. Imaizumi, H. Shirahata, A. Suzuki, Y. Matsuda, T. Arai, Y. Soejima, M. Sawabe, et al. Cytological characteristics of poorly differentiated Squamous Cell Carcinomas (SCC) of the breast: Comparison between cytological findings of invasive ductal carcinoma and apocrine carcinoma. VIRCHOWS ARCHIV. 2016. 469. S94-S94
  • A. Seki, K. Chida, T. Sugiyama, H. Kitahata, A. Hamamatsu, M. Sawabe, Y. Matsuda, K. Nonaka, K. Harada, T. Arai. Can increased intraplaque microvessels predict acute coronary event? A pathologic study of coronary arteries in 894 human autopsy cases. VIRCHOWS ARCHIV. 2016. 469. S68-S68
  • Atsuko Seki, Koji Chida, Akihiko Hamamatsu, Motoji Sawabe, Yoko Matsuda, Keisuke Nonaka, Shinichiro Ohkawa, Tomio Arai. Erosion Is More Common as a Cause of AMI in the Elderly: A Pathologic Study of Coronary Arteries in 884 Human Autopsy Cases. MODERN PATHOLOGY. 2016. 29. 85A-85A
  • Atsuko Seki, Koji Chida, Akihiko Hamamatsu, Motoji Sawabe, Yoko Matsuda, Keisuke Nonaka, Shinichiro Ohkawa, Tomio Arai. Erosion Is More Common as a Cause of AMI in the Elderly: A Pathologic Study of Coronary Arteries in 884 Human Autopsy Cases. LABORATORY INVESTIGATION. 2016. 96. 85A-85A
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Books (1)：
  • スタンダード病理学 第4版
    文光堂 2016
Lectures and oral presentations  (74)：
  • COVID-19 における嗅覚障害の残存と属性との関連
    (第15回 日本臨床検査学教育学会学術大会 2021)
  • Analysis of function and gene expression in ITGB6 knockout cholangiocarcinoma cells
    (The 110th Annual Meeting of the Japanese Society of Pathology 2021)
  • ITGB6 knockout and functional analysis in cholangiocarcinoma cells
    (The 56th Annual Meeting of Liver Cancer Study Group of Japan 2020)
  • Search for a Practical Immunohistochemical Method to Identify Human Atrioventricular Conduction Axis
    (第109回日本病理学会総会 2020)
  • Launch of a system of immunohistochemistry at a national hospital for cancer treatment in Cambodia
    (第109回日本病理学会総会 2020)
ｍore...
Education (2)：
  • - 1987 Tokyo Medical and Dental University Graduate School, Division of Medicine
  • - 1983 Tokyo Medical and Dental University Faculty of Medicine
Professional career (1)：
  • Degree of Doctor (Tokyo Medical and Dental University)
Work history (7)：
  • 2020/04/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Biomedical Sciences and Engineering Division of Biomedical Laboratory Sciences Department of Molecular Pathology Professor
  • 2012/04 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Department of Molecular Pathology
  • 2018/04/01 - 2020/03/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Biomedical Sciences and Engineering Division of Biomedical Laboratory Sciences Department of Molecular Pathology Professor
  • 2012/04/01 - 2018/03/31 Tokyo Medical and Dental University Graduate School of Health Care Sciences Biomedical Laboratory Sciences Moleculo-genetic Sciences Molecular Pathology Professor
  • 1992/04/01 - 2012/03/31 東京都健康長寿医療センター 病理部門 部長
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Association Membership(s) (6)：
JAPAN HUMAN PROTEOME ORGANIZATION ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPAN SOCIETY OF HEPATOLOGY ,  JAPANESE CIRCULATION SOCIETY ,  THE JAPANESE SOCIETY OF CLINICAL CYTOLOGY ,  THE JAPANESE SOCIETY OF PATHOLOGY
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