Rchr
J-GLOBAL ID:201201094343621513   Update date: Feb. 01, 2024

Tamura Tomohiko

タムラ トモヒコ | Tamura Tomohiko
Affiliation and department:
Other affiliations (2):
Homepage URL  (1): http://www-user.yokohama-cu.ac.jp/~immunol/
Research field  (2): Hematology and oncology ,  Immunology
Research keywords  (12): Monocytes/macrophages ,  Dendritic cells ,  Immune responses ,  Cell proliferation ,  Epigenome ,  Differentiation ,  Transcription factors ,  免疫 制御学 ,  血液免疫学 ,  造血幹細胞移植学 ,  血液内科学 ,  サイトカイン
Research theme for competitive and other funds  (30):
  • 2023 - 2025 転写因子・液-液相分離依存性クロマチンドメインによる免疫細胞分化制御
  • 2022 - 2025 膵癌における腫瘍関連マクロファージのマスター転写因子を標的とした新規治療法への探索研究(代表)
  • 2021 - 2024 Single-Cell RNA sequenceによるARDS病態の網羅的探索
  • 2021 - 2024 インターフェロン制御因子5を標的とした急性呼吸窮迫症候群の分子標的治療の開発
  • 2021 - 2024 Higher-order chromatin structure dynamics during dendritic cell development in vivo
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Papers (140):
  • Kenji Kubara, Kazuto Yamazaki, Takayuki Miyazaki, Keita Kondo, Daisuke Kurotaki, Tomohiko Tamura, Yuta Suzuki. Lymph node macrophages drive innate immune responses to enhance the anti-tumor efficacy of mRNA vaccines. Molecular therapy : the journal of the American Society of Gene Therapy. 2024
  • Shunichiro Tsukamoto, Toru Suzuki, Hiromichi Wakui, Tatsuki Uehara, Juri Ichikawa, Hiroshi Okuda, Kotaro Haruhara, Kengo Azushima, Eriko Abe, Shohei Tanaka, et al. Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity. Metabolism: clinical and experimental. 2023. 149. 155706-155706
  • Ryosuke Jikuya, Todd A Johnson, Kazuhiro Maejima, Jisong An, Young-Seok Ju, Hwajin Lee, Kyungsik Ha, WooJeung Song, Youngwook Kim, Yuki Okawa, et al. Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinoma. EBioMedicine. 2023. 92. 104596-104596
  • Shintaro Watanuki, Hiroshi Kobayashi, Yuki Sugiura, Masamichi Yamamoto, Daiki Karigane, Kohei Shiroshita, Yuriko Sorimachi, Shuhei Koide, Motohiko Oshima, Akira Nishiyama, et al. Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis. 2023
  • Naoki Ikeda, Hiroaki Kubota, Risa Suzuki, Mitsuki Morita, Ayana Yoshimura, Yuya Osada, Keigo Kishida, Daiki Kitamura, Ayaka Iwata, Satoshi Yotsumoto, et al. The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell Reports. 2023. 42. 3. 112165-112165
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MISC (51):
  • 藩龍馬, 佐藤豪, 菊地雅子, 菊地雅子, 西村謙一, 吉見竜介, 桐野洋平, 松本佳子, 日原裕恵, 伊藤昌史, et al. 全身性エリテマトーデスにおける転写因子IRF5の阻害は現行治療法の限界を克服した新規治療法となる可能性がある. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2021. 85th (CD-ROM)
  • 佐藤豪, 藩龍馬, 菊地雅子, 菊地雅子, 真鍋昭雄, 田形典子, 西村謙一, 吉見竜介, 桐野洋平, 松本佳子, et al. 転写因子IRF5を標的とした全身性エリテマトーデスの新規治療法開発. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2019. 84th
  • Koichi Murakami, Daisuke Kurotaki, Wataru Kawase, Shunsuke Soma, Yumi Fukuchi, Hiroyoshi Kunimoto, Ryusuke Yoshimi, Shuhei Koide, Motohiko Oshima, Takako Hishiki, et al. Regulation of Mitophagy By O-Linked N-Acetylglucosamine Transferase Is Essential for Hematopoietic Stem Cell Maintenance. BLOOD. 2018. 132
  • 村上 紘一, 黒滝 大翼, 川瀬 航, 相馬 俊介, 福地 由美, 國本 博義, 吉見 竜介, 小出 周平, 大島 基彦, 小田 真由美, et al. O-GlcNAc化による造血幹細胞ミトコンドリアダイナミクスの制御(O-GlcNAcylation is critical for mitochondrial dynamics in hematopoietic stem cells). 臨床血液. 2018. 59. 9. 1483-1483
  • KANAMORI Heiwa, SASAKI Shin, UEDA Seiji, YAMAZAKI Etsuko, TAMURA Tomohiko, HARANO Hiroshi, MATSUZAKI Michio, OGAWA Kouji, MOHRI Hiroshi, OKUBO Takao. Graft-versus-leukemia Effect Induced by Abrupt Discontinuation of Cyclosporine A Following Allogeneic Bone Marrow Transplantation. 1998. 38. 8. 643-646
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Education (2):
  • 1991 - 1995 Yokohama City University Graduate Graduate School of Medicine
  • 1984 - 1990 Yokohama City University
Professional career (1):
  • 博士(医学) (横浜市立大学)
Work history (14):
  • 2018/10 - 現在 Yokohama City University Advanced Medical Research Center
  • 2012/09 - 現在 Yokohama City University Advanced Medical Research Center
  • 2009/09 - 現在 Yokohama City University Graduate School of Medicine, Graduate
  • 2018/04 - 2023/03 Yokohama City University Graduate School of Medicine, Graduate
  • 2007/07 - 2009/08 The University of Tokyo Graduate School of Medicine
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Association Membership(s) (7):
INTERNATIONAL CYTOKINE & INTERFERON SOCIETY ,  THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS ,  THE AMERICAN SOCIETY OF HEMATOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY OF HEMATOLOGY
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