Rchr
J-GLOBAL ID：201201097980635144   Update date: Feb. 23, 2024

Nagae Masamichi

ナガエ マサミチ | Nagae Masamichi
Affiliation and department：
大阪大学 微生物病研究所

About 大阪大学 微生物病研究所


Job title： 助教
Research field  (1)： Structural biochemistry
Research keywords  (2)： 包括脳ネットワーク ,  Structural Biology
Research theme for competitive and other funds  (13)：
  • 2022 - 2027 Identification of self-derived molecules recognized by immune sensors
  • 2021 - 2025 免疫細胞レクチンシグレックの新規リガンド結合部位の証明と新しい免疫制御機構の解明
  • 2020 - 2023 Structural studies on the variety and universality of GlcNAc transferases
  • 2017 - 2020 Structural studies on meta-stable conformations of bisected glycan
  • 2015 - 2017 Structural studies on the pathological mechanism of dystroglycanopathy
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Papers (64)：
  • Shotaro Mori, Masamichi Nagae, Sho Yamasaki. Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. International Immunology. 2024
  • Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, et al. Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology. 2024. 9. 91. eade6924
  • Reina F Osuka, Masamichi Nagae, Akito Ohuchi, Shiho Ohno, Yoshiki Yamaguchi, Yasuhiko Kizuka. The cancer-associated glycosyltransferase GnT-V (MGAT5) recognizes the N-glycan core via residues outside its catalytic pocket. FEBS letters. 2023
  • Shigenari Ishizuka, J Hessel M van Dijk, Tomomi Kawakita, Yuji Miyamoto, Yumi Maeda, Masamichi Goto, Guillaume Le Calvez, L Melanie Groot, Martin D Witte, Adriaan J Minnaard, et al. PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. ACS central science. 2023. 9. 7. 1388-1399
  • Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, et al. Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2. eLife. 2022. 11
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MISC (60)：
  • 長田 菜緒子, 長江 雅倫, 中の 三弥子, Mishra Sushil K., Doerksen Robert J., 舘野 浩章, 木塚 康彦. 糖転移酵素GnT-IVファミリーが持つユニークなレクチンドメインの役割. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-030]
  • 長田菜緒子, 長江雅倫, 長江雅倫, 中の三弥子, MISHRA Sushil K., DOERKSEN Robert J., 木塚康彦, 木塚康彦. Recognition of self N-glycan by lectin domain of GnT-IV glycosyltransferase. 日本糖質学会年会要旨集. 2023. 42nd
  • 橋本雄太, 川出遥加, 森井爽, 中の三弥子, 長江雅倫, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of the regulatory mechanisms of intracellular activity of GnT-III K346T mutant. 日本糖質学会年会要旨集. 2023. 42nd
  • 富田晟太, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of regulation mechanisms of activity of fucosyltransferase FUT8. 日本糖質学会年会要旨集. 2023. 42nd
  • 長田 菜緒子, 長江 雅倫, 木塚 康彦. 糖転移酵素GnT-IVa,-IVbの糖タンパク質基質に対する選択性の研究. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 3T02a-06
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Lectures and oral presentations  (58)：
  • A transient metabolite in Mycobacterium leprae PGL-I biosynthesis pathway is a potent PAMP
    (U.S.-Japan Cooperative Medical Sciences Program 2023)
  • Structural studies of public TCR against SARS-CoV-2 peptide clarified the broad spectrum of the clonotype
    (2022)
  • Self-antigen for mucosal-associated invariant T (MAIT) cell
    (2022)
  • Self-antigen for mucosal-associated invariant T (MAIT) cells
    (The 1st International School on Advanced Immunology 2022)
  • レクチン受容体による結晶性物質の認識機構に関する構造基盤の解明
    (第41回日本糖質学会年会 2022)
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Education (3)：
  • 2001 - 2004 Yokohama City University Graduate
  • 1999 - 2001 Kyoto University Graduate School of Science
  • 1995 - 1999 Kyoto University, Faculty of Science
Professional career (1)：
  • 博士(理学) (横浜市立大学)
Work history (8)：
  • 2020/04 - 現在 (兼任)大阪国際がんセンター
  • 2020/01 - 現在 Osaka University Research Institute for Microbial Diseases
  • 2019/04 - 現在 (兼任)名古屋大学大学院医学研究科 非常勤講師
  • 2016/10 - 2020/01 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
  • 2013/04 - 2016/10 (兼任)東京医科歯科大学大学院 医歯学総合研究科 非常勤講師
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Awards (2)：
  • 2014/11 - 東京糖鎖研究会(GlycoTokyo) 奨励賞
  • 2011/06 - PSSJ Young Scientist Award
Association Membership(s) (5)：
THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN ,  PROTEIN SCIENCE SOCIETY OF JAPAN
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