Kitatani Kazuyuki

キタタニカズユキ | Kitatani Kazuyuki

Affiliation and department：
Homepage URL (2)： http://www.setsunan.ac.jp/~p-yakko/ , http://db.tohoku.ac.jp/whois/e_detail/5156cd9fe2d5f274358122fb0a6a8c81.html

Research field (6)： Pharmaceuticals - chemistry and drug development , Obstetrics and gynecology , Clinical pharmacy , Pharmaceuticals - health and biochemistry , Pharmacology , Tumor diagnostics and therapeutics

Research keywords (11)：リポソーム創薬 , lipid biochemistry , sphingotherapy , cancer therapy , ceramide liposome , 薬理学 , cancer , necroptosis , ceramide , sphingolipids , cancer biology

Research theme for competitive and other funds (16)：

2022 - 2025 Molecular mechanism of ceramide-governed necroptosis
2021 - 2024 頭頸部癌を標的としたセラミドリポソーム製剤による治療探索
2017 - 2023 子宮頸部非扁平上皮癌に対する新たな治療法確立の試み
2020 - 2021 ネクロプトーシス制御機構の解明と創薬基盤の創出
2016 - 2019 Roles for ceramide in ovarian cancer

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Papers (81)：

Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, et al. Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells. Cells. 2024. 13. 405
Hayato Shimora, Masaya Matsuda, Naoki Takemoto, Miku Nomura, Junpei Hamaguchi, Ryogo Terakawa, Miki Inaba, Kazuyuki Kitatani, Takeshi Nabe. Steroid-Insensitive Gene Expression of Extracellular Matrix Components and Pro-fibrotic Factors in the Lung Associated with Airway Hyperresponsiveness in Murine Asthma. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 227-231
Harumi Sakae, Yuri Ogiso, Masaya Matsuda, Hayato Shimora, Tye Deering, Todd Fox, Mark Kester, Takeshi Nabe, Kazuyuki Kitatani. Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma. Cells. 2023. 12. 4. 591
Masaya Matsuda, Seito Shimizu, Kazuyuki Kitatani, Takeshi Nabe. Extracellular Vesicles Derived from Allergen Immunotherapy-Treated Mice Suppressed IL-5 Production from Group 2 Innate Lymphoid Cells. Pathogens. 2022. 11. 11. 1373-1373
Masaya Matsuda, Miki Inaba, Junpei Hamaguchi, Hiro Tomita, Miyu Omori, Hayato Shimora, Harumi Sakae, Kazuyuki Kitatani, Takeshi Nabe. Local IL-10 replacement therapy was effective for steroid-insensitive asthma in mice. International Immunopharmacology. 2022. 110. 109037-109037

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MISC (24)：

張雪薇, 北谷和之. 脂質を介したネクロプトーシス制御. 生化学. 2018. 90. 6. 797-800
北谷和之, 張雪薇, 豊島将文, Kester Mark, 八重樫伸生. 卵巣がん細胞に対するセラミドナノリポソームの抗腫瘍効果ネクロプトーシスの誘導(その2). 脂質生化学研究. 2017. 59. 181-182
北谷和之. 東北からバイオバンク試料・情報の分譲東北大学東北メディカル・メガバンク機構. 生化学. 2017. 89. 930-931
張雪薇, 豊島将文, 石橋ますみ, 臼井利典, 湊純子, 重田昌吾, Kester Mark, 八重樫伸生, 北谷和之. 卵巣がん細胞に対するセラミドナノリポソームの抗腫瘍効果ネクロプトーシスの誘導. 脂質生化学研究. 2016. 58. 68-69
北谷和之, 張雪薇, 臼井利典, 豊島将文, 重田昌吾, Egiz Mahy, 湊純子, 石橋ますみ, 小木曽英夫, 岡崎俊朗, et al. セラミド合成酵素による癌転移制御. 脂質生化学研究. 2016. 58. 182-182

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Books (4)：

セラミド研究の新展開
食品化学新聞社 2019
がん転移学の基礎研究:卵巣癌の分子機構
日本臨床 2017
セラミドの細胞内機能概論:スフィンゴミエリン合成酵素ファミリー
2011
Generation of signaling molecules by de novo sphingolipid synthesis
Springer 2006

Lectures and oral presentations (28)：

極長鎖セラミド依存的なネクロプトーシスの誘導
(第15回セラミド研究会学術集会・第16回スフィンゴテラピィ研究会合同年会 2022)
Involvement of sphingolipids in the regulation of necroptosis: development of sphingolipids-based therapy for cancer
(Symposium S44 Sphingolipid biology and therapy 2021)
Symposium S44 Sphingolipid biology and therapy: Closing remarks
(2021)
Involvement of sphingolipids in the regulation of programmed necrosis: development of sphingolipids-based therapy for cancer
(14th Sphingotherapy Conference 2020)
リポソーム化セラミドの抗腫瘍活性:プログラム化ネクローシスの誘導
(日本薬理学会近畿部会 2018)

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Education (3)：

1999 - 2002 京都薬科大学大学院博士後期課程薬学専攻
1997 - 1999 京都薬科大学大学院博士前期課程薬学専攻
1993 - 1997 Kyoto Pharmaceutical University Pharmaceutical Sciences

Professional career (1)：

PhD (京都薬科大学)

Work history (11)：

2024/04 - 現在 Setsunan University Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry Professor
2021/04 - 2024/03 Setsunan University
2018/04 - 2021/03 Setsunan University Faculty of Pharmaceutical Sciences Associate Professor
2017/04 - 2018/03 Tohoku University
2017/04 - 2018/03 Tohoku University

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Committee career (12)：

2023/04 - 現在日本薬理学会学術評議員
2019/09 - 現在 Diseases 誌 Editorial Board
2019/07 - 現在 Cells 誌 Editorial Board
2019/06 - 現在スフィンゴテラピィ研究会組織委員長
2023/11 - 2024/03 Cells, Special Issues, Novel Therapeutic Targets and Approaches, Genetic Markers and Signaling Pathways in Neoplasms Special Issue Editor

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Awards (4)：

2016 - European Journal of Surgical Oncology Outstanding Contribution in Reviewing
2012/04 - Gaucher Generation Program (Sanofi) Young Investigator Award
2006/11 - 41th Annual Southeaster Regional Lipid Conference Travel Award
2004/11 - 39th Annual Southeaster Regional Lipid Conference Postdoctral Award

Association Membership(s) (9)：

日本癌学会 , セラミド研究会 , スフィンゴテラピィ研究会 , THE JAPANESE PHARMACOLOGICAL SOCIETY , 日本眼薬理学会 , 日本生化学会 , ASBMB , 日本薬学会 , 日本脂質生化学会

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