Katsuda Yousuke

カツダヨウスケ | Katsuda Yousuke

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Homepage URL (1)： http://www.analyticalchemistry-ihara-lab.com/

Research field (4)： Biochemistry , Nanobioscience , Nanomaterials , Molecular biology

Research keywords (3)：核酸医薬 , 核酸化学 , chemical biology

Research theme for competitive and other funds (14)：

2023 - 2026 New technologies for RNA structural regulation that enables the control and analysis of cellular function
2021 - 2025 日本発の革新的バイオ医薬開発を目指した細胞内RNA機能の制御機構の解明と創薬応用
2022 - 2025 Staple核酸を用いたHIV感染症の新たな治療法に関する研究基盤の創出
2022 - 2025 Development of novel mode of action nucleic-acid-medicine
2021 - 2024 Development of Nucleic-Acid-Medicine Mechanisms by Staple Oligomer

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Papers (38)：

Yousuke Katsuda, Takuto Kamura, Tomoki Kida, Takeru Saeki, Yua Itsuki, Yuri Kato, Taishi Nakamura, Motohiro Nishida, Yusuke Kitamura, Toshihiro Ihara, et al. In Vivo mRNA Hacking with Staple Oligomers Prevents Myocardial Hypertrophy. 2023
Takuto Kamura, Yousuke Katsuda, Yusuke Fuchigami, Yua Itsuki, Yusuke Kitamura, Toshihiko Sakurai, Takeaki Ozawa, Toshihiro Ihara. RNA Aptamer-Based Approach to Inhibiting Split-GFP Reconstruction and the Loss of Inhibitory Activity Using Complementary RNA. Bulletin of the Chemical Society of Japan. 2023. 96. 3. 241-246
Yousuke Katsuda, Shin-ichi Sato, Maimi Inoue, Hisashi Tsugawa, Takuto Kamura, Tomoki Kida, Rio Matsumoto, Sefan Asamitsu, Norifumi Shioda, Shuhei Shiroto, et al. Small molecule-based detection of non-canonical RNA G-quadruplex structures that modulate protein translation. Nucleic Acids Research. 2022
Toshihiro Ihara, Yusuke Kitamura, Yousuke Katsuda. Metal Ion-Directed Specific DNA Structures and Their Functions. Life. 2022. 12. 5. 686-686
Ken Natsuga, Yoshikazu Furuta, Shota Takashima, Takuma Nohara, Hsin-Yu Huang, Satoru Shinkuma, Hideki Nakamura, Yousuke Katsuda, Hideaki Higashi, Chao-Kai Hsu, et al. Cas9-guided haplotyping of three truncation variants in autosomal recessive disease. Human mutation. 2022. 43. 7. 877-881

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MISC (22)：

木田朋輝, 勝田陽介, 嘉村匠人, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. In vivo suppression of target gene expression by XNAs Staple based on RNA hacking technology. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
千々岩風音, 北村裕介, 林榛菜, 中島雄太, 安田敬一郎, 岩槻政晃, 熊本清太郎, 勝田陽介, 中西義孝, 馬場秀夫, et al. Reversible capture of circulating tumor cells in blood using an anti-EpCAM aptamer-modified gold filter. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
五木結愛, 勝田陽介, 北村祐介, 井原敏博. Novel mechanism of gene expression control technology using RNA hacking. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
木田朋輝, 勝田陽介, 北村裕介, 萩原正規, 佐藤慎一, 井原敏弘. Next generation nucleic-acid medicine that suppresses gene expression by XNA’s free pass Staple system. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
松本理緒, 勝田陽介, 溝上潤一, 北村裕介, 井原敏博. Development of self-circularization DNA/RNA mixmer staple nucleic acids with non-canonical structures for enhanced nuclease resistance. 日本化学会春季年会講演予稿集(Web). 2022. 102nd

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Patents (4)：

Lectures and oral presentations (42)：

Staple核酸を利用したRNA hackingによる新規核酸医薬の開発
(The 143rd Annual Meeting of the Pharmaceutical Society of Japan 2023)
Staple核酸による標的RNA構造制御技術
(2022)
Development of a next-generation nucleic acid medicine
(1st Forum on Biomedical Research & Innovation by iCeMS, Kyoto University and Shenyang Pharmaceutical University 2020)
Comprehensive search for the G-quadruplex structure in RNA using an RGB-1
(The 14th International Student Conference on Advanced Science and Technology 2019)
Development of a novel technology for suppression of gene expression based on specific secondary structure induction in RNA by staple oligomer
(The 14th International Student Conference on Advanced Science and Technology 2019)

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Professional career (1)：

Work history (8)：

2023/04 - 現在京都大学物質-細胞統合システム拠点客員准教授
2023/01 - 現在 Kumamoto University Faculty of Advanced Science and Technology Associate Professor
2022/02 - 現在 StapleBio.Inc Chief Scientific Officer
2017/05 - 現在 Kyoto University Institute for Integrated Cell-Material Sciences
2017/04 - 現在 Kumamoto University Faculty of Advanced Science and Technology Assistant Professor

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Awards (5)：

2021/10 - Leave a Nest Grand Prize
2019/09 - The Japan Society for Analytical Chemistry. 分析化学会奨励賞核酸を使った生体分子観察システムの開発及び RNA 非標準型特殊核酸構造同定システムの開発
2019/08 - 特別賞 Development of a next-generation nucleic acid medicine for treating rare disease
2012/03 - 日本化学会日本化学会第92春季年会学生講演賞 DNA ナノ構造体を用いたDNA 組み換え酵素Cre の反応機構の検討
2010/03 - 日本化学会日本化学会第90春季年会学生講演賞 DNAナノ構造体によるDNA修飾及び修復酵素の反応制御

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