Rchr
J-GLOBAL ID：201301001158150708   Update date: Jan. 30, 2024

Matsumaru Takanori

Matsumaru Takanori
Affiliation and department：
Keio University Faculty of Science and Technology Department of Chemistry

About Keio University Faculty of Science and Technology Department of Chemistry


Research field  (1)： Bioorganic chemistry
Research keywords  (6)： 糖脂質 ,  創薬化学 ,  生物有機化学 ,  ケミカルバイオロジー ,  天然物全合成 ,  有機合成化学
Research theme for competitive and other funds  (3)：
  • 2021 - 2025 免疫調節性複合脂質の合成・機能の理解と展開
  • 2020 - 2023 自然免疫受容体Mincleのリガンド合成を基盤とした分子認識および細胞内挙動解析
  • 2017 - 2020 Synthesis and biofunctional elucidation of complex lipids involved in biological defense
Papers (33)：
  • Atsushi Furukawa, Yusuke Shuchi, Jiaqi Wang, Pablo Adrian Guillen-Poza, Shigenari Ishizuka, Misuzu Kagoshima, Risa Ikeno, Hiroyuki Kumeta, Sho Yamasaki, Takanori Matsumaru, et al. Structural basis for plastic glycolipid recognition of the C-type lectin Mincle. Structure. 2023
  • Aoi Kimishima, Hiroyasu Ando, Goh Sennari, Yoshihiko Noguchi, Shogo Sekikawa, Toru Kojima, Motoyoshi Ohara, Yoshihiro Watanabe, Yuki Inahashi, Hirokazu Takada, et al. Chemical Degradation-Inspired Total Synthesis of the Antibiotic Macrodiolide, Luminamicin. Journal of the American Chemical Society. 2022
  • Takanori Matsumaru, Kodai Sueyoshi, Kana Okubo, Shusuke Fujii, Kasumi Sakuratani, Ryota Saito, Kazunari Ueki, Sho Yamasaki, Yukari Fujimoto. Trehalose diesters containing a polar functional group-modified lipid moiety: Synthesis and evaluation of Mincle-mediated signaling activity. Bioorganic and Medicinal Chemistry. 2022. 75
  • Takanori Matsumaru, Kodai Sueyoshi, Kana Okubo, Shusuke Fujii, Kasumi Sakuratani, Ryota Saito, Kazunari Ueki, Sho Yamasaki, Yukari Fujimoto. Trehalose diesters containing a polar functional group-modified lipid moiety: Synthesis and evaluation of Mincle-mediated signaling activity. Bioorganic & medicinal chemistry. 2022. 75. 117045-117045
  • Takanori Matsumaru, Kasumi Sakuratani, Saeko Yanaka, Koichi Kato, Sho Yamasaki, Yukari Fujimoto. Fungal β-Mannosyloxymannitol Glycolipids and Their Analogues: Synthesis and Mincle-Mediated Signaling Activity. European Journal of Organic Chemistry. 2022. 2022. 20
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MISC (16)：
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Lectures and oral presentations  (29)：
  • Synthetic study of dragmacidins using photochemical reaction
    (The 14th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC) 2018)
  • Modulation of molecular recognition and bioactivities of immunostimulatory glycolipids by lipid chain modification with polar functional group
    (29th International Carbohydrate Symposium (ICS2018) 2018)
  • Synthesis and immunomodulatory activities of glycoconjugates containing lysophosphatidyl inositol
    (29th International Carbohydrate Symposium (ICS2018) 2018)
  • Chemical synthesis and signaling activity of conjugated lipids through C-type lectin receptor Mincle (招待講演)
    (INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2018)
  • Synthetic study of dragmacidins via decarboxylative alkynylation using visible-light-mediated photoredox catalysis in a flow system
    (The First International Conference on Automated Flow and Microreactor Synthesis (ICAMS-1) 2018)
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Education (2)：
  • 2008 - 2011 Kitasato University Graduate School of Infectioncontrol Sciences
  • 2006 - 2008 Kitasato University Graduate School of Infectioncontrol Sciences
Professional career (1)：
  • 博士(生命科学) (北里大学)
Work history (5)：
  • 2017/10 - 現在 Keio University Faculty of Science and Technology
  • 2013/01 - 2017/09 Hokkaido University Faculty of Pharmaceutical Sciences
  • 2012/04 - 2012/12 コロラド州立大学化学科 博士研究員 (Adviser: Professor John L. Wood) 北里大学生命科学研究所 研究員
  • 2011/04 - 2012/03 コロラド州立大学化学科 博士研究員 (Adviser: Professor John L. Wood) 上原記念生命科学財団 海外留学助成ポストドクトラルフェローシップ
  • 2009/04 - 2011/03 日本学術振興会特別研究員 (DC2) (指導教授: 砂塚敏明教授)
Committee career (1)：
  • 2017/12 - 2018/05 慶應有機化学若手シンポジウム実行委員 第6回慶應有機化学若手シンポジウム実行委員
Association Membership(s) (4)：
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE CHEMICAL SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
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