Rchr
J-GLOBAL ID：201301002035033746
Update date: Feb. 01, 2024
Aoki-Utsubo Chie
ウツボ チエ | Aoki-Utsubo Chie
Affiliation and department：
Job title：
Assistant Professor
Research field (3)：
Pharmaceuticals - health and biochemistry
, Virology
, Pharmaceuticals - chemistry and drug development
Research keywords (9)：
脂質
, carbohydrate-related inhibitors
, dengue virus
, hepatitis B virus
, hepatitis C virus
, infectious control
, natural products-derived drugs
, antiviral
, flavivirus
Research theme for competitive and other funds (4)：
- 2021 - 2023 新型コロナウイルス感染増殖における脂質代謝系の役割の解明
- 2018 - 2021 インドネシアの薬用植物からの抗 B 型肝炎ウイルス新規リード化合物の探索と開発研究
- 2018 - 2019 インドネシア産植物に含まれるフェノール性水酸基化合物からの新規肝炎ウイルス治療薬シーズの探索
- 2016 - 2019 インドネシアにおける肝疾患の早期診断治療への教育システムの確立
Papers (34)：
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Chie Aoki-Utsubo, Muhammad Hanafi, Destia Tri Armanti, Hiroyuki Fuchino, Nobuo Kawahara, Sri Hartati, Aty Widyawaruyanti, Pratiwi Sudarmono, Masanori Kameoka, Hak Hotta. Identification of an Oligostilbene, Vaticanol B, from Dryobalanops aromatica Leaves as an Antiviral Compound against Hepatitis C Virus. Biol. Pharm. Bull. 2023. 46. 8. 1079-1087
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Chie Aoki-Utsubo, Puguh Indrasetiawan, Kento Fukano, Masamichi Muramatsu, Nina Artanti, Muhammad Hanafi, Hak Hotta, Masanori Kameoka. Amentoflavone inhibits hepatitis B virus infection via the suppression of preS1 binding to host cells. Microbiology and immunology. 2023
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Tutik Sri Wahyuni, Nida S. Sukma, Adita A. Permanasari, Chie Aoki-Utsubo, Aty Widyawaruyanti, Achmad Fuad Hafid. Acacia mangium: A promising plant for isolating anti-hepatitis C virus agents. F1000Research. 2023. 11. 1452-1452
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Adita Ayu Permanasari, Chie Aoki-Utsubo, Tutik Sri Wahyuni, Lidya Tumewu, Myrna Adianti, Aty Widyawaruyanti, Hak Hotta, Achmad Fuad Hafid. An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs. BMC Complementary Medicine and Therapies. 2021. 21. 1
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Aty Widyawaruyanti, Mulyadi Tanjung, Adita Ayu Permanasari, Ratih Saputri, Lidya Tumewu, Myrna Adianti, Chie Aoki-Utsubo, Hak Hotta, Achmad Fuad Hafid, Tutik Sri Wahyuni. Alkaloid and benzopyran compounds of Melicope latifolia fruit exhibit anti-hepatitis C virus activities. BMC Complementary Medicine and Therapies. 2021. 21. 1
ｍore...
MISC (4)：
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堀田博, 靭千恵, 西本幸子, 増井涼, 杉本智潮, 清水康晴, 須藤慶一, 河上仁美, 渕野裕之, 川原信夫, et al. Antiviral Activity of Toad Cake and Its Compounds Bufalin and Gamabufotalin against Hepatitis C Virus and Dengue Virus. 甲南女子大学研究紀要2. 2022. 16
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Wahyuni TS, Aoki Utsubo C, HOTTA HAK. Promising anti-hepatitis C virus compounds from natural resources. Natural Product Communications. 2016. 11. 8. 1193-1200
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Akihiro, Yamada, Ken Hatano, Koji Matsuoka, Yasuaki Esumi, Chie Aoki, Kazuya Hidari, Yasuo Suzuki, Daiyo Terunuma. Syntheses and Biological Assay of a Series of Lacto-N-neotetraose Cluster using Carbosilane Dendrimer Scaffolds. The 14th International Symposium on Organosilicon Chemistry. 2005. 134
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KIPJ Hidari, C Aoki, T Ogi, S Itonori, F Hasebe, K Morita, M Sugita, T Takahashi, CT Guo, D Miyamoto, et al. Isolation and characterization of glycolipids recognized with dengue virus type 2 from human and mosquito cells. GLYCOBIOLOGY. 2004. 14. 11. 1158-1158
Lectures and oral presentations (56)：
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新型コロナウイルスは肝細胞でアポリポプロテインBを利用して増殖する
(2023)
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硫酸単糖型抗デングウイルス薬の合成研究(3)
(2023)
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A biflavonid amentoflavone inhibits hepatitis B virus infection
(2021)
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A biflavonoid amentoflavone inhibits hepatitis B virus infection
(2021)
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Methyl-pheophorbide A and porphyrin derivatives inhibit the viral assembly step of hepatitis C virus
(HCV2021: The International Symposium on Hepatitis C Virus and Related Viruses 2021)
ｍore...
Education (1)：
- - 2007 University of Shizuoka Graduate School of Pharmaceutical Sciences Doctor Course
Professional career (2)：
- 修士(薬学) (静岡県立大学)
- 博士(薬学) (静岡県立大学)
Work history (3)：
- 2014/04 - 2015/03 Kobe University, Graduate School of Medicine, Center for Infectious Diseases
- 2010/04 - 2014/02 インドネシア大学医学部
- 2007/04 - 2010/03 中国科学院微生物研究所
Awards (1)：
- 2014/11 - 細菌学会関西支部総会 若手研究者奨励賞
Association Membership(s) (3)：
THE JAPANESE SOCIETY OF PHARMACOGNOSY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY FOR VIROLOGY
