Yoshizawa-Sugata Naoko

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/30344071.ja.html

Research keywords (26)： endogenous retrovirus , 2-cell zygote , ES cells , Rif1 , DNA複製 , ゲノム安定性 , 複製フォーク , AND-1 , 複製チェックポイント , 相同組換え修復 , DNA損傷 , ゲノム不安定性 , Timeless , 姉妹染色体交換 , 非相同末端結合修復 , Tipin , Cdc7 , フォーク保護因子 , 複製保護因子 , 複製ストレス , DNA修復 , 複製起点 , in vitro DNA複製 , 細胞周期 , oriP , MCM

Research theme for competitive and other funds (8)：

2021 - 2024 Elucidation of de novo gene birth and pseudogenization processes via reconstruction of ancestral transcriptional regulation
2019 - 2022 Porphyrin-based imaging probe for the detection of oncogene promoter quadruplex DNA
2015 - 2018 Functional analysis of Rif1 in regulating muticopy gene cluster and super state of pluripotent stem cells
2011 - 2015 Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication
2011 - 2014 Mechanism of the replication stress response of variable replication fork complexes

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Papers (20)：

Tamas Nemeth, Naoko Yoshizawa-Sugata, Agnes Pallier, Youichi Tajima, Yue Ma, Éva Tóth, Hisao Masai, Yoko Yamakoshi. Water-Soluble Gd(III)-Porphyrin Complexes Capable of Both Photosensitization and Relaxation Enhancement. Chemical & Biomedical Imaging. 2023
Yuichiro Hara, Takuma Kumamoto, Naoko Yoshizawa-Sugata, Kumiko Hirai, Song Xianghe, Hideya Kawaji, Chiaki Ohtaka-Maruyama. Spatial transcriptome of developmental mouse brain reveals temporal dynamics of gene expressions and heterogeneity of the claustrum. 2023
Naoko Yoshizawa-Sugata, Hisao Masai. Histone Modification Analysis of Low-Mappability Regions. Methods in molecular biology (Clifton, N.J.). 2023. 2519. 163-185
Naoko Yoshizawa-Sugata, Satoshi Yamazaki, Kaoru Mita-Yoshida, Tomio Ono, Yasumasa Nishito, Hisao Masai. Loss of full-length DNA replication regulator Rif1 in two-cell embryos is associated with zygotic transcriptional activation. The Journal of biological chemistry. 2021. 101367-101367
Aless, ro Fracassi, Yoko Yamakoshi, Rong Zhou, Hisao Masai, Wendelin Jan Stark, Korinne Liosi, Ankita Ray, Jean-Pascal Bourgeois, Stephan H, et al. LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis. Chemical Science. 2020. 11. 44. 11998-12008

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Work history (3)：

2022/04 - 現在お茶の水女子大学大学院客員准教授
2020/04 - 現在 Tokyo Metropolitan Institute of Medical Science Research Center for Genome & Medical Sciences Chief Researcher
2017/04 - 2020/03 Tokyo Metropolitan Institute of Medical Science Dep. Genome Medicine Chief Researcher

Association Membership(s) (1)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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