Rchr
J-GLOBAL ID:201301020066560050   Update date: Apr. 18, 2024

Furukawa Atsushi

フルカワ アツシ | Furukawa Atsushi
Affiliation and department:
Job title: Associate Professor
Research field  (7): Pharmaceuticals - health and biochemistry ,  Molecular biology ,  Immunology ,  Cell biology ,  Biophysics ,  Functional biochemistry ,  Structural biochemistry
Research keywords  (9): タンパク質 ,  Immune Receptor ,  Antibody ,  Immunology ,  Innate Immunity ,  Structural Analysis ,  Interaction Analysis ,  Allergy ,  MicroED
Research theme for competitive and other funds  (6):
  • 2023 - 2026 IgE受容体(FcεRI)立体構造解析を基盤としたアレルギー・免疫制御機構の解明
  • 2020 - 2023 免疫活性化受容体LILRA2のリガンド認識機構の解明
  • 2022 - 2023 新規アレルギー制御分子Ly6G の標的分子の探索と創薬への応用
  • 2018 - 2020 ナノディスクを用いた免疫受容体Mincleのコレステロール認識機構の解明
  • 2018 - 2019 ナノディスクを用いた免疫受容体Mincleの糖脂質認識機構の解明
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Papers (25):
  • Atsushi Furukawa, Hiroyuki Kumeta, Takashi Saitoh, Katsumi Maenaka. Protocol to identify the ligand binding site of Mincle using NMR spectroscopy. STAR protocols. 2024. 5. 2. 102996-102996
  • Marin Sakamoto, Yuka Nagata, Atsushi Furukawa, Tomoyuki Kusada, Shohei Inamoto, Tomomi Senda, Naohide Hirashima, Ryo Suzuki. VAMP7 knockdown in secretory granules impairs CCL2 secretion in mast cells. Biochemical and Biophysical Research Communications. 2023
  • Atsushi Furukawa, Yusuke Shuchi, Jiaqi Wang, Pablo Adrian Guillen-Poza, Shigenari Ishizuka, Misuzu Kagoshima, Risa Ikeno, Hiroyuki Kumeta, Sho Yamasaki, Takanori Matsumaru, et al. Structural basis for plastic glycolipid recognition of the C-type lectin Mincle. Structure. 2023
  • Chisato Amma, Yayoi Inomata, Risa Kohno, Minami Satake, Atsushi Furukawa, Yuka Nagata, Hironori Sugiyama, Takafumi Seto, Ryo Suzuki. Copper in airborne fine particulate matter (PM2.5) from urban sites causes the upregulation of pro-inflammatory cytokine IL-8 in human lung epithelial A549 cells. Environmental geochemistry and health. 2023. 45. 8. 5879-5891
  • Eiki Tomita, Masahiro Kojima, Yuki Nagashima, Ken Tanaka, Haruki Sugiyama, Yasutomo Segawa, Atsushi Furukawa, Katsumi Maenaka, Satoshi Maeda, Tatsuhiko Yoshino, et al. An Electron-Deficient CpE Iridium(III) Catalyst: Synthesis, Characterization, and Application to Ether-Directed C-H Amidation. Angewandte Chemie (International ed. in English). 2023. 62. 21. e202301259
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MISC (34):
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Books (2):
  • 創薬研究のための相互作用解析パーフェクト : 低中分子・抗体創薬におけるスクリーニング戦略と実例、in silico解析、一歩進んだ分析技術まで
    羊土社 2021 ISBN:9784758122566
  • Furukawa, A., Kita, S., Tadokoro, T., Fukuhara, H., & Maenaka, K. (2016). Structural Aspects of C-Type Lectin Receptors. In C-Type Lectin Receptors in Immunity (pp. 179-190). Springer Japan.
Lectures and oral presentations  (3):
  • 免疫受容体のリガンド認識機構の解明と創薬への応用
    (第92回日本寄生虫学会大会サテライトミーティング(第35回 分子生物学・生理生化学研究会) 2023)
  • 免疫受容体PILRαの糖ペプチド認識機構解明とその創薬への応用
    (第51回ペプチド夏の勉強会 2019)
  • 免疫受容体のリガンド認識機構の解明
    (日本生化学会 東北支部 第85回例会・シンポジウム 2019)
Education (3):
  • 2008 - 2012 Gunma University Graduate School of Medicine
  • 2004 - 2006 Hokkaido University Graduate School of Science Chemistry division
  • 2000 - 2004 Hokkaido University School of Science Chemistry
Professional career (1):
  • 博士(医学) (群馬大学)
Work history (5):
  • 2021/11 - 現在 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences Faculty of Pharmacy Associate Professor
  • 2015/04 - 2021/10 Hokkaido University Faculty of Pharmaceutical Sciences Assistant Professor
  • 2013/11 - 2015/03 Hokkaido University Faculty of Pharmaceutical Sciences Specially Appointed Assistant Professor
  • 2012/04 - 2013/10 Hokkaido University Faculty of Pharmaceutical Sciences Postdoctoral Fellow
  • 2006/04 - 2007/03 JSR Corporation Fine Electronic Materials Research Laboratory, Semiconductor Material division Researcher
Awards (2):
  • 2018/07 - 日本生化学会北海道支部 平成30年度 日本生化学会北海道支部会若手奨励賞 免疫細胞表面受容体のリガンド認識機構
  • 2013/08 - Poster Award (Journal of Structural and Functional Genomics -Bronze-) in ICSG2013-SLS, Sapporo, 2013 July, Structural basis of glycolipids recognition mechanisms by C-type lectin like receptor, Mincle
Association Membership(s) (7):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本アレルギー学会
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