Rchr
J-GLOBAL ID：201301037614367433   Update date: Feb. 04, 2024

Amano Masayuki

アマノ マサユキ | Amano Masayuki
Affiliation and department：
Kumamoto University

About Kumamoto University


Homepage URL  (2)： http://kaken.nii.ac.jp/d/r/30575080.ja.html ,  https://www.researchgate.net/profile/Masayuki_Amano
Research field  (1)： Infectious disease
Research keywords  (7)： Infectious disease ,  HIV-1 ,  HBV ,  SARS-CoV-2 ,  SARS-CoV-2 vaccine ,  Drug development ,  Translational research
Research theme for competitive and other funds  (20)：
  • 2022 - 2025 Development of novel HIV-1 capsid (CA) inhibitor, and investigation regarding novel mechanism of CA uncoating
  • 2018 - 2021 JSPS KAKENHI Grant Number 18K08435
  • 2017 - 2020 Takeda Science Foundation (Osaka, Japan) Grant for Medical Research
  • 2019 - 2020 Japan Agency for Medical Research and Development/Center for Clinical and Translational Research of Kyushu University, Grant-in-Aid for Scientific Research/Seeds A
  • 2018 - 2019 Terumo Foundation for Life Sciences and Arts, Grant for Research Development
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Papers (69)：
  • Masayuki Amano, Yasuko Ichikawa, Shota Matsumoto, Shuzo Matsushita, Shinya Shimada, Hiroaki Mitsuya. Longitudinal analysis of neutralization in sera from HCWs receiving 2 doses of Omicron BA.4/5-adapted bivalent vaccine. Journal of infection. 2023. 87. 5. e79-e82
  • Takuya Kobayakawa, Masayuki Amano, Miyuki Nakayama, Kohei Tsuji, Takahiro Ishii, Yutaro Miura, Kouki Shinohara, Kenichi Yamamoto, Masao Matsuoka, Hirokazu Tamamura. Development of anti-HBV agents targeting HBV capsid proteins. RSC medicinal chemistry. 2023. 14. 10. 1973-1980
  • Masayuki Amano, Sachiko Otsu, Yukari Uemura, Yasuko Ichikawa, Shota Matsumoto, Nobuyo Higashi-Kuwata, Shuzo Matsushita, Shinya Shimada, Hiroaki Mitsuya. Neutralization against Omicron sublineages (BA.2/BA.5/BQ.1.1/XBB/XBB.1.5) in bivalent BNT162b2-vaccinated HCWs with or without risk factors, or following BT infection with Omicron. Scientific reports. 2023. 13. 1. 17404
  • Masayuki Amano, Sachiko Otsu, Yukari Uemura, Yasuko Ichikawa, Shota Matsumoto, Nobuyo Higashi-Kuwata, Shuzo Matsushita, Shinya Shimada, Hiroaki Mitsuya. Neutralization against Omicron sublineages (BA.2/BA.5/BQ.1.1/XBB/XBB.1.5) in bivalent BNT162b2-vaccinated HCWs with or without risk factors, or following BT infection with Omicron. Research Square. 2023
  • Ghosh, A.K., Mishevich, J.L., Kovela, S., Shaktah, R., Ghosh, A.K., Johnson, M., Wang, Y.-F., Wong-Sam, A., Agniswamy, J., Amano, M., et al. Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation. European Journal of Medicinal Chemistry. 2023. 255. 115385
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MISC (44)：
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Patents (4)：
  • 抗 HIV 医薬組成物
  • 抗HIV医薬組成物(出願番号:PCT/JP2020/021080号)
  • 抗HIV医薬組成物(出願番号:2019-102088号)
  • 抗HIV医薬組成物(出願番号:2017-244763号)
Lectures and oral presentations  (65)：
  • 感染性 SARS-CoV-2 変異株とComirnaty (BNT162b2) 接種後の医療従事者血清及び IgG を用いた、ワクチン後獲得免疫の長期フォローアップ解析
    (第36回日本エイズ学会学術集会・総会(静岡・アクトシティ浜松/web) 2022)
  • 感染性 SARS-CoV-2 変異株とComirnaty (BNT162b2) 接種後の医療従事者血清及び IgG を用いた、ワクチン後獲得免疫の長期フォローアップ
    (第30 回日本抗ウイルス療法学会学術集会・総会(京都リサーチパーク) 2022)
  • HIV-1 capsid(CA)を標的とする新規抗HIV-1阻害剤の作用機序の解明
    (第35回日本エイズ学会学術集会・総会(東京・グランドプリンスホテル高輪/web) 2021)
  • HIV-1 capsid (CA) 構造蛋白に作用し、その過剰安定化を誘導する事でHIV-1増殖阻害活性を発揮する化合物群(CA hyper-stabilizers)、ACAi-010, -024の同定
    (第35回日本エイズ学会学術集会・総会(東京・グランドプリンスホテル高輪/web) 2021)
  • 感染効率を上昇させるHIV-1ヌクレオカプシド内に認められた薬剤耐性変異
    (第34回日本エイズ学会学術集会・総会 2020)
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Education (2)：
  • - 2008 Graduate school of medical science, Kumamoto university, Ph.D.
  • - 1999 Kumamoto university, School of medicine, M.D.
Professional career (2)：
  • M.D. (Kumamoto University)
  • Ph.D. (Kumamoto University)
Work history (12)：
  • 2022/05 - Joint research Center for Human Retrovirus Infection, Kumamoto University
  • 2016 - 2022 Kumamoto University Hospital Departments of Hematology, collagen diseases, infectious diseases. Assistant Professor
  • 2013 - 2016 Assistant Professor, Kumamoto University, Departments of Hematology, collagen diseases, infectious diseases.
  • 2008 - 2013 Research Associate, Kumamoto University, Departments of Hematology, collagen diseases, infectious diseases.
  • 2011 - 2011 Guest Researcher, Experimental Retrovirology Section, National Cancer Institute, NIH, Bethesda, MD, United States.
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Awards (6)：
  • 2020/03 - The Kumamoto Medical Society (93rd Annual Meeting) Kumamoto Medical Society Research Award
  • 2015/06 - Hakuba Symposium (17th Annual Meeting) Best Poster Award
  • 2014/05 - The Japanese Association for Antiviral Therapy (24th Annual Meeting) Shiota Award
  • 2013/08 - Hakuba Symposium (15th Annual Meeting) Best Poster Award
  • 2011/04 - Kumamoto University AIDS Global COE Program International Research Scientist Development Awards
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Association Membership(s) (5)：
JAPANESE SOCIETY OF CHEMOTHERAPY ,  American Society for Microbiology ,  The Japanese Association for Antiviral Therapy ,  THE JAPANESE SOCIETY FOR AIDS RESEARCH ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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