Rchr
J-GLOBAL ID:201301039014236346   Update date: Feb. 01, 2024

MARI GOTOH

ゴトウ マリ | MARI GOTOH
Affiliation and department:
Research field  (1): Molecular biology
Research keywords  (1): 生理活性脂質
Research theme for competitive and other funds  (4):
  • 2023 - 2026 新規リゾホスファチジン酸構造異性体の定量法確立と生理活性解明
  • 2019 - 2022 神経保護作用を持つ生理活性脂質の新規メカニズムの解明: 脳血管障害治療への応用
  • 2014 - 2018 Analysis of lipid mediator signaling that increases hyaluronic acid synthesis and the effect of lipid mediator on cell senescence
  • 2010 - 2012 Investigation of the mechanism of TRP channel mediated by a lipid mediator, 2ccPA, via LPA receptor
Papers (57):
  • Wataru Nagata, Mari Gotoh, Akiho Koizumi, Keiko Fukasawa, Keiichi Nakagawa, Yasushi Satoh, Toshiaki Ishizuka. Two-carba cyclic phosphatidic acid treatment promotes phenotypic switch from M1 to M2 microglia and prevents behavioral abnormalities in a mouse model of neuropsychiatric systemic lupus erythematosus. Human cell. 2023
  • Misaki Endo, Mari Gotoh, Mari Nakashima, Yuka Kawamoto, Shiho Sakai, Kimiko Murakami-Murofushi, Kei Hashimoto, Yasunori Miyamoto. 2-Carba cyclic phosphatidic acid regulates blood coagulation and fibrinolysis system for repair after brain injury. Brain research. 2023. 148511-148511
  • Wataru Nagata, Akiho Koizumi, Keiichi Nakagawa, Sayaka Takahashi, Mari Gotoh, Yasushi Satoh, Toshiaki Ishizuka. Treatment with lysophosphatidic acid prevents microglial activation and depression-like behaviours in a murine model of neuropsychiatric systemic lupus erythematosus. Clinical and experimental immunology. 2023
  • Rino Takei, Mari Nakashima, Mari Gotoh, Misaki Endo, Kei Hashimoto, Yasunori Miyamoto, Kimiko Murakami-Murofushi. 2-carba-cyclic phosphatidic acid modulates astrocyte-to-microglia communication and influences microglial polarization towards an anti-inflammatory phenotype. Neuroscience letters. 2023. 797. 137063-137063
  • Mari GOTOH, Yasunori Miyamoto, Hiroko Ikeshima-Kataoka. Astrocytic Neuroimmunological Roles Interacting with Microglial Cells in Neurodegenerative Diseases. International Journal of Molecular Sciences. 2023
more...
MISC (26):
  • 武井理乃, 中島麻里, 後藤真里, 遠藤美沙紀, 宮本泰則, 宮本泰則, 室伏きみ子. Effect of Cyclic Phosphatidic Acid (2ccPA) on Microglial Polarization During Traumatic Brain Injury. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 遠藤美沙紀, 遠藤美沙紀, 後藤真里, 後藤真里, 中島麻里, 中島麻里, 武井理乃, 武井理乃, 室伏きみ子, 池島(片岡)宏子, et al. Suppression of hemorrhage by the lipid mediator 2-carba cyclic phosphatidic acid in traumatic brain injury. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 中島麻里, 中島麻里, 後藤真里, 後藤真里, 橋本恵, 室伏きみ子, 池島(片岡)宏子, 宮本泰則, 宮本泰則. The neuroprotective effect of tenascin-C via astrocytes in traumatic brain injury. 日本結合組織学会学術大会抄録集. 2021. 53rd. 68-68
  • 共同報告者, リーダー, 小野寺洋子, サブリーダー, 室伏きみ子, 研究者, 後藤真里ら. “複合乳酸菌発酵法を利用した大豆を原料とする抗ストレス食品素材の開発”. 成 28年度 戦略的基盤技術高度化・連携支援事業、戦略的基盤技術高度化支援事業、研究開発成果等報告書、全ページ20. 2017
  • 中島進吾, 後藤真里, 深澤桂子, 室伏きみ子. 初代培養アストロサイトにおける脂肪滴蓄積の影響. 日本栄養・食糧学会大会講演要旨集. 2017. 71st
more...
Patents (5):
Books (3):
  • Q&Aシリーズ 炎症・感染症 (全108ページ)
    国立大学法人 お茶の水女子大学 ヒューマンライフイノベーション開発研究機構 2021
  • Biomimetic
    2011
  • “Biodiversity in biomembranes” (学位論文)
    2006
Lectures and oral presentations  (73):
  • “Biosynthesis of β-lysophosphatidic acid from cyclic phosphatidic acid by autotaxin, and bioactivity of a novel β-lysophosphatidic acid analogue, 2-carba-lysophosphatidic acid”
    (The Lysophospholipid and Related Mediators Conference: From Bench to Clinic-Virtual 2021)
  • The effect of cyclic phosphatidic acid derivative 2-carba-cPA on repair of brain stab wound
    (2020)
  • “2-carba cyclic phosphatidic acid contributes to the neuroprotection in stab-wounded cerebral cortex via regulation of astrocytes”
    (American Society for Cell Biology, Washington D.C 2019)
  • 「マウス大脳皮質穿刺損傷時のアストロサイトにおける2ccPAのテネイシンC発現への効果」
    (第6回Matricellフォーラム、仙台 2019)
  • 2 carba cyclic phosphatidic acid suppresses the activation of astrocytes in the stab wounded mouse cerebral cortex
    (2019)
more...
Education (4):
  • - 2006 Université Louis Pasteur
  • - 2006 Ochanomizu University
  • - 2003 Ochanomizu University
  • - 2001 Ochanomizu University Faculty of Science Division of Chemistry
Professional career (2):
  • PhD (Université Louis Pasteur (Universite Strasbourg I))
  • PhD (Ochanomizu University)
Work history (9):
  • 2022/04 - 現在 Ochanomizu University
  • 2022/04 - 現在 Faculty of Medical Technology, Teikyo University
  • 2016/04 - 2022/03 Ochanomizu University Institute for Human Life Innovation
  • 2019/04 - 2021/03 Otsuma Women's University
  • 2018/04 - 2021/03 東京女子医科大学附属看護専門学校 非常勤講師
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