Rchr
J-GLOBAL ID：201301041258514024   Update date: Mar. 23, 2024

Kitagawa Daiju

キタガワ ダイジユ | Kitagawa Daiju
Affiliation and department：
Graduate School of Pharmaceutical Sciences, The University of Tokyo Laboratory of Physiological Chemistry

About Graduate School of Pharmaceutical Sciences, The University of Tokyo Laboratory of Physiological Chemistry


Job title： Professor
Research field  (1)： Cell biology
Research keywords  (7)： phase transition ,  phase separation ,  細胞分裂 ,  中心小体 ,  染色体不安定化 ,  中心体 ,  微小管形成中心
Research theme for competitive and other funds  (10)：
  • 2019 - 2024 Comprehensive analysis of molecular machineries for mitotic spindle formation in human cells and its application to development of next generation anti-cancer drug.
  • 2017 - 2019 Towards understanding the mechanisms how lncRNAs regulate mitotic spindle assembly and chromosome segregation
  • 2016 - 2019 Self-assembly mechanisms of centrioles in nanoscape
  • 2016 - 2018 The role of the cartwheel structure in human centriole duplication
  • 2016 - 2018 Analysis of a novel lncRNA that regulates human chromosome segregation
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Papers (50)：
  • Yutaka Takeda, Takumi Chinen, Shunnosuke Honda, Sho Takatori, Shotaro Okuda, Shohei Yamamoto, Masamitsu Fukuyama, Koh Takeuchi, Taisuke Tomita, Shoji Hata, et al. Molecular basis promoting centriole triplet microtubule assembly. Nature Communications. 2024. 15. 1
  • Tomoki Harada, Shoji Hata, Rioka Takagi, Takuma Komori, Masamitsu Fukuyama, Takumi Chinen, Daiju Kitagawa. An antioxidant screen identifies ascorbic acid for prevention of light-induced mitotic prolongation in live cell imaging. Communications biology. 2023. 6. 1. 1107-1107
  • Akira Mabuchi, Shoji Hata, Mariya Genova, Chiharu Tei, Kei K Ito, Masayasu Hirota, Takuma Komori, Masamitsu Fukuyama, Takumi Chinen, Atsushi Toyoda, et al. ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid RPE1 and HCT116 cells. BMC genomics. 2023. 24. 1. 289-289
  • Takuma Komori, Shoji Hata, Akira Mabuchi, Mariya Genova, Tomoki Harada, Masamitsu Fukuyama, Takumi Chinen, Daiju Kitagawa. A CRISPR-del-based pipeline for complete gene knockout in human diploid cells. Journal of cell science. 2023. 136. 6
  • Akihiro Tanaka, Tomomi Nakano, Kento Watanabe, Kazutoshi Masuda, Gen Honda, Shuichi Kamata, Reitaro Yasui, Hiroko Kozuka-Hata, Chiho Watanabe, Takumi Chinen, et al. Stress-dependent cell stiffening by tardigrade tolerance proteins that reversibly form a filamentous network and gel. PLoS biology. 2022. 20. 9. e3001780
ｍore...
MISC (5)：
Lectures and oral presentations  (5)：
  • 中心小体複製の分子機構の解析
    (中心小体研究会 2011)
  • Cracking the mystery of nine-ness
    (2011)
  • 中心小体複製の分子機構の解明
    (2011)
  • The mechanisms of centriole formation
    (2011)
  • Structural basis of 9-fold symnetry of centrioles
    (Sinergia grant meeting 2011)
Work history (2)：
  • 2018/04 - 現在 東京大学大学院薬学系研究科 教授
  • 2011/02 - 2018/03 国立遺伝学研究所 その他
Awards (5)：
  • 2021 - 日本学術振興会 日本学術振興会賞
  • 2017/03 - Kazato Research foundation Kazato Award
  • 2017 - KSBMB 韓国分子生物生化学会) NETWORK AWARD
  • 2016/09 - The Japanese Biochemical Society Young Investigator Award
  • 2013 - 平成25年度科学技術分野の文部科学大臣表彰若手科学者賞
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